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The map label for this gene is fur [H]

Identifier: 39996481

GI number: 39996481

Start: 1507920

End: 1508351

Strand: Direct

Name: fur [H]

Synonym: GSU1379

Alternate gene names: 39996481

Gene position: 1507920-1508351 (Clockwise)

Preceding gene: 39996480

Following gene: 39996482

Centisome position: 39.54

GC content: 59.49

Gene sequence:

>432_bases
ATGAAGCGGGCAAAAAAGCAGATCTTCCATGATTACATCGCCAAGCACGGGCTCAAGTCGACCCGCCAGCGGGATATCAT
TCTTGATGCCTTCCTCTCCACCGACCGCCACCTGAGCATCGAGGAGCTGTACCTCAAGCTCAGGGCAAAGCACCCGAACA
TTGGTTACGCCACGGTCTACCGCACCCTCAAGCTGTTCGCGGAATCGGGCATCGCCCGGGAGATGCAGTTCGGCGACGGT
CAGACCCGCTACGAGCACGTGACCGAAGGTGAGCACCACGACCACCTGGTCTGTACCGGGTGCGGCGCCATCATCGAGTT
CGAGAACGAGGCCATCGAGAAGTTGCAGGACGATGTGGCCGCGGCCCACGACTTCGTCATCACCACCCATAAGCTTGAGT
TGTACGGTCTCTGCGCCGCCTGTCGCAAATAG

Upstream 100 bases:

>100_bases
GGTGAGGCTTCGTTAATCGCTCTCATCTAAGTGATATTTAGTCTTGACGGATCCGGCCGGGCCTTCTATGATGATATTCA
CTTTCAGTTGAGGGTGGTCC

Downstream 100 bases:

>100_bases
GGCTGATCGTGCCGCGCCGTCCGACGGCCCGGCACTTTTCCCGCGGCGATGTCTGAAAGTGATTTTCACTAGCATAAGAG
GCTCATGCAAAACGGTATGA

Product: ferric uptake regulation protein Fur

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKRAKKQIFHDYIAKHGLKSTRQRDIILDAFLSTDRHLSIEELYLKLRAKHPNIGYATVYRTLKLFAESGIAREMQFGDG
QTRYEHVTEGEHHDHLVCTGCGAIIEFENEAIEKLQDDVAAAHDFVITTHKLELYGLCAACRK

Sequences:

>Translated_143_residues
MKRAKKQIFHDYIAKHGLKSTRQRDIILDAFLSTDRHLSIEELYLKLRAKHPNIGYATVYRTLKLFAESGIAREMQFGDG
QTRYEHVTEGEHHDHLVCTGCGAIIEFENEAIEKLQDDVAAAHDFVITTHKLELYGLCAACRK
>Mature_143_residues
MKRAKKQIFHDYIAKHGLKSTRQRDIILDAFLSTDRHLSIEELYLKLRAKHPNIGYATVYRTLKLFAESGIAREMQFGDG
QTRYEHVTEGEHHDHLVCTGCGAIIEFENEAIEKLQDDVAAAHDFVITTHKLELYGLCAACRK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=134, Percent_Identity=42.5373134328358, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16385; Mature: 16385

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAKKQIFHDYIAKHGLKSTRQRDIILDAFLSTDRHLSIEELYLKLRAKHPNIGYATVY
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
RTLKLFAESGIAREMQFGDGQTRYEHVTEGEHHDHLVCTGCGAIIEFENEAIEKLQDDVA
HHHHHHHHCCCHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHH
AAHDFVITTHKLELYGLCAACRK
HHHHHEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRAKKQIFHDYIAKHGLKSTRQRDIILDAFLSTDRHLSIEELYLKLRAKHPNIGYATVY
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
RTLKLFAESGIAREMQFGDGQTRYEHVTEGEHHDHLVCTGCGAIIEFENEAIEKLQDDVA
HHHHHHHHCCCHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHH
AAHDFVITTHKLELYGLCAACRK
HHHHHEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]