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The map label for this gene is cysW [H]

Identifier: 39996450

GI number: 39996450

Start: 1475038

End: 1475868

Strand: Direct

Name: cysW [H]

Synonym: GSU1348

Alternate gene names: 39996450

Gene position: 1475038-1475868 (Clockwise)

Preceding gene: 39996449

Following gene: 39996451

Centisome position: 38.67

GC content: 67.39

Gene sequence:

>831_bases
ATGCCATCATCCATCCGCACCCGTACCGAACCGGCCCCGGTCCGCTGGGCGCTCACCGCCGGCGCGCTCCTGTTCCTCGG
CCTCTTTCTCTTCGTGCCCCTGGCCGCGGTCTTTGCCCAGGCCCTGGAAAAGGGGTGGGGCGCCTACCTGGCCGCCATCC
GCGAGCCCGACGCCCTGGCGGCGGTGAAGCTGACCCTCGTCACAGCCGCCATCAGCGTTCCCCTGAACCTGGTCTTCGGC
GTGGTCGCGGCCTGGGCCATCGCCAAGTTCCAGTTCCGGGGCAAGCAGCTCCTGATCACCCTGATCGATCTGCCGTTTTC
GGTGTCGCCGGTCATCTCGGGCCTGATCTACGTCCTGCTGTTCGGGCTCCAGGGATGGCTCGGCCCCTGGCTCCAGGACC
ACGACGCGAAGATCATCTTCGCCGTGCCCGGCATCGTCCTGGCCACGGTCTTCGTCACCTTCCCCTTCGTGGCCCGGGAG
CTGATCCCGCTCATGGAGGCCCAGGGCACGGACGAGGAAGAGGCGGCCATCACCCTGGGGGCGAACGGCTTCCAGACCTT
TTGGCGGGTGACCCTCCCCAACATCAAGTGGGGGCTCCTTTACGGGGTGATCCTGTGCAACGCCCGGGCAATGGGCGAGT
TCGGCGCGGTCTCGGTGGTTTCCGGCCATATCCGGGGCGAGACCAACACCATCCCCCTCCACGTGGAGATCCTCTACAAC
GAGTACAACTACGCCGCCGCCTTTGCCGTGGCCTCGCTCCTGGCCCTGCTGGCCCTGGTCACCCTGGTCCTGAAGAGCGT
GGTCGAGTGGCGGATGCGCGCCGACGCCTGA

Upstream 100 bases:

>100_bases
GCCACGGTGATGCTCCTGTTCTCGTTCCTGATGCTCCTGGCCGTGAACCTGCTCCAGAAGTGGAGCCGGCGCCACGCCGC
CTGACCCGGAGGACCCGACC

Downstream 100 bases:

>100_bases
CCCGGACGCCGCAGCGAAATAAAGGAACCAAGACATGAGCATCGAGATCGCCAACGTCACCAAGCAGTTCGGCAGCTTCA
CCGCCCTGGACAACGTGAAC

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPSSIRTRTEPAPVRWALTAGALLFLGLFLFVPLAAVFAQALEKGWGAYLAAIREPDALAAVKLTLVTAAISVPLNLVFG
VVAAWAIAKFQFRGKQLLITLIDLPFSVSPVISGLIYVLLFGLQGWLGPWLQDHDAKIIFAVPGIVLATVFVTFPFVARE
LIPLMEAQGTDEEEAAITLGANGFQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTIPLHVEILYN
EYNYAAAFAVASLLALLALVTLVLKSVVEWRMRADA

Sequences:

>Translated_276_residues
MPSSIRTRTEPAPVRWALTAGALLFLGLFLFVPLAAVFAQALEKGWGAYLAAIREPDALAAVKLTLVTAAISVPLNLVFG
VVAAWAIAKFQFRGKQLLITLIDLPFSVSPVISGLIYVLLFGLQGWLGPWLQDHDAKIIFAVPGIVLATVFVTFPFVARE
LIPLMEAQGTDEEEAAITLGANGFQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTIPLHVEILYN
EYNYAAAFAVASLLALLALVTLVLKSVVEWRMRADA
>Mature_275_residues
PSSIRTRTEPAPVRWALTAGALLFLGLFLFVPLAAVFAQALEKGWGAYLAAIREPDALAAVKLTLVTAAISVPLNLVFGV
VAAWAIAKFQFRGKQLLITLIDLPFSVSPVISGLIYVLLFGLQGWLGPWLQDHDAKIIFAVPGIVLATVFVTFPFVAREL
IPLMEAQGTDEEEAAITLGANGFQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTIPLHVEILYNE
YNYAAAFAVASLLALLALVTLVLKSVVEWRMRADA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=269, Percent_Identity=52.4163568773234, Blast_Score=291, Evalue=3e-80,
Organism=Escherichia coli, GI1788764, Length=215, Percent_Identity=38.1395348837209, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786980, Length=215, Percent_Identity=32.5581395348837, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29892; Mature: 29760

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSIRTRTEPAPVRWALTAGALLFLGLFLFVPLAAVFAQALEKGWGAYLAAIREPDALA
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVKLTLVTAAISVPLNLVFGVVAAWAIAKFQFRGKQLLITLIDLPFSVSPVISGLIYVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHH
FGLQGWLGPWLQDHDAKIIFAVPGIVLATVFVTFPFVARELIPLMEAQGTDEEEAAITLG
HHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
ANGFQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTIPLHVEILYN
CCCHHHHHEEECCCCHHHHHHHHHHHCCHHCCCCCCHHEEEEEECCCCCEEEEEEEEEEE
EYNYAAAFAVASLLALLALVTLVLKSVVEWRMRADA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSSIRTRTEPAPVRWALTAGALLFLGLFLFVPLAAVFAQALEKGWGAYLAAIREPDALA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVKLTLVTAAISVPLNLVFGVVAAWAIAKFQFRGKQLLITLIDLPFSVSPVISGLIYVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHH
FGLQGWLGPWLQDHDAKIIFAVPGIVLATVFVTFPFVARELIPLMEAQGTDEEEAAITLG
HHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
ANGFQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTIPLHVEILYN
CCCHHHHHEEECCCCHHHHHHHHHHHCCHHCCCCCCHHEEEEEECCCCCEEEEEEEEEEE
EYNYAAAFAVASLLALLALVTLVLKSVVEWRMRADA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]