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The map label for this gene is tcmO [H]

Identifier: 39996316

GI number: 39996316

Start: 1317073

End: 1318074

Strand: Direct

Name: tcmO [H]

Synonym: GSU1214

Alternate gene names: 39996316

Gene position: 1317073-1318074 (Clockwise)

Preceding gene: 39996313

Following gene: 39996317

Centisome position: 34.53

GC content: 63.97

Gene sequence:

>1002_bases
ATGGAACCGAAAAACTGGACACCGGCAGAACTCTTGCAACTTTCGAGTGGCTACTGGAACATCGGCGCGCTCCACGCCGC
AGTGAGTCTCGATGTCTTTACTCCTCTTGCCGGTGGTGATCTCTCTGCCGAGGAACTTGCGGAACGGTTGGGCGCCGACG
GCCGGGCTCTCGCCATGCTCCTTGATGCCCTGACCGCCATGGAGCTTGTGCACAAGCGGGCAGACCGCTACGGGGCAGCG
CCCGCCGCCTGTCGCTTTCTCTCGCAGGATTCGCCCGATTACCTGGGCCATATCATCAGGCATCACCATCACCTGGTGGC
CGGGTGGGCGCGTCTGGACGATGCGGTGCGCAGCGGCGGGCCGGTTCGGCAAAGCTCGTCCCACGGCAGCGACGAATCAG
CGCGGGAGAGCTTCCTGATGGGCATGTTCAACCTGGCCATGCTGTCGGCTCCGCGGGTGGTGCCCCGGATCGATCTTTCA
GGACGGCAACGGCTCCTGGACCTGGGGGGCGGCCCCGGCACCTGGGCCATCCAGTTCTGTCTCCACAACCCCGGGCTTCG
GGCCGTGGTCTACGACCTTCCCACCACCCGCCCCTTTGCCGAGCGGACCATAGCCCGCTTCGGTCTGGCAGATCGGGTTT
CCTTCGAGGAGGGGAATTTTCTCTCCGGGGAAATCCCGGGGAGGTACGATGTGGCCTGGCTCTCCCAGATTCTTCATTCC
GAGGGGCCCGAAGGGTGCGCCGTCGTTATTGAAAAGGCGGTGACAGCCCTCGAACCGGGAGGCATCATCATGGTGCAGGA
GTTTATCCTGAACGATGCCAAGGACGGTCCGCTCTTTCCGGCCCTCTTTTCACTGAACATGCTGGTGGGGACAGCGCGGG
GGCAGGCCTATACCGAAGGTGAGCTGAAGGCCATGATGGCGGCAGCCGGCGTGCGCGACCTGCGACGCATTCCCCTGGAT
ATCCCCAACGGCGCTGGCGTCATTGCCGGGACCGTTGCCTGA

Upstream 100 bases:

>100_bases
AGGATCTTGCATATTTCAGTGACGCGGGTATGTTCATTGTCATTATCCCGTGGTTGAGCCATTCTCGGCCGCGGGAGACA
GCTGTCGACCGGAGGCACGC

Downstream 100 bases:

>100_bases
GGTGTCATCCCTTCATGAACAACGGCACGCCTGAGCATACCGGGCAACGGCCCGAGCAGTGGCTCATGGGCGAGGCCCGG
CAGGTGCGGGGACCTCTCCT

Product: tetracenomycin polyketide synthesis 8-o-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEPKNWTPAELLQLSSGYWNIGALHAAVSLDVFTPLAGGDLSAEELAERLGADGRALAMLLDALTAMELVHKRADRYGAA
PAACRFLSQDSPDYLGHIIRHHHHLVAGWARLDDAVRSGGPVRQSSSHGSDESARESFLMGMFNLAMLSAPRVVPRIDLS
GRQRLLDLGGGPGTWAIQFCLHNPGLRAVVYDLPTTRPFAERTIARFGLADRVSFEEGNFLSGEIPGRYDVAWLSQILHS
EGPEGCAVVIEKAVTALEPGGIIMVQEFILNDAKDGPLFPALFSLNMLVGTARGQAYTEGELKAMMAAAGVRDLRRIPLD
IPNGAGVIAGTVA

Sequences:

>Translated_333_residues
MEPKNWTPAELLQLSSGYWNIGALHAAVSLDVFTPLAGGDLSAEELAERLGADGRALAMLLDALTAMELVHKRADRYGAA
PAACRFLSQDSPDYLGHIIRHHHHLVAGWARLDDAVRSGGPVRQSSSHGSDESARESFLMGMFNLAMLSAPRVVPRIDLS
GRQRLLDLGGGPGTWAIQFCLHNPGLRAVVYDLPTTRPFAERTIARFGLADRVSFEEGNFLSGEIPGRYDVAWLSQILHS
EGPEGCAVVIEKAVTALEPGGIIMVQEFILNDAKDGPLFPALFSLNMLVGTARGQAYTEGELKAMMAAAGVRDLRRIPLD
IPNGAGVIAGTVA
>Mature_333_residues
MEPKNWTPAELLQLSSGYWNIGALHAAVSLDVFTPLAGGDLSAEELAERLGADGRALAMLLDALTAMELVHKRADRYGAA
PAACRFLSQDSPDYLGHIIRHHHHLVAGWARLDDAVRSGGPVRQSSSHGSDESARESFLMGMFNLAMLSAPRVVPRIDLS
GRQRLLDLGGGPGTWAIQFCLHNPGLRAVVYDLPTTRPFAERTIARFGLADRVSFEEGNFLSGEIPGRYDVAWLSQILHS
EGPEGCAVVIEKAVTALEPGGIIMVQEFILNDAKDGPLFPALFSLNMLVGTARGQAYTEGELKAMMAAAGVRDLRRIPLD
IPNGAGVIAGTVA

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI283549144, Length=154, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157168360, Length=154, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI117553627, Length=326, Percent_Identity=24.8466257668712, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI291045183, Length=326, Percent_Identity=24.8466257668712, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI291045181, Length=326, Percent_Identity=24.8466257668712, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016461
- InterPro:   IPR001077
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00891 Methyltransf_2 [H]

EC number: NA

Molecular weight: Translated: 35726; Mature: 35726

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKNWTPAELLQLSSGYWNIGALHAAVSLDVFTPLAGGDLSAEELAERLGADGRALAML
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHH
LDALTAMELVHKRADRYGAAPAACRFLSQDSPDYLGHIIRHHHHLVAGWARLDDAVRSGG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVRQSSSHGSDESARESFLMGMFNLAMLSAPRVVPRIDLSGRQRLLDLGGGPGTWAIQFC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHCCCCCCCCEEEEEE
LHNPGLRAVVYDLPTTRPFAERTIARFGLADRVSFEEGNFLSGEIPGRYDVAWLSQILHS
ECCCCCEEEEEECCCCCHHHHHHHHHHCCHHCCCCCCCCEECCCCCCCCCHHHHHHHHHC
EGPEGCAVVIEKAVTALEPGGIIMVQEFILNDAKDGPLFPALFSLNMLVGTARGQAYTEG
CCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
ELKAMMAAAGVRDLRRIPLDIPNGAGVIAGTVA
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MEPKNWTPAELLQLSSGYWNIGALHAAVSLDVFTPLAGGDLSAEELAERLGADGRALAML
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHH
LDALTAMELVHKRADRYGAAPAACRFLSQDSPDYLGHIIRHHHHLVAGWARLDDAVRSGG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVRQSSSHGSDESARESFLMGMFNLAMLSAPRVVPRIDLSGRQRLLDLGGGPGTWAIQFC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHCCCCCCCCEEEEEE
LHNPGLRAVVYDLPTTRPFAERTIARFGLADRVSFEEGNFLSGEIPGRYDVAWLSQILHS
ECCCCCEEEEEECCCCCHHHHHHHHHHCCHHCCCCCCCCEECCCCCCCCCHHHHHHHHHC
EGPEGCAVVIEKAVTALEPGGIIMVQEFILNDAKDGPLFPALFSLNMLVGTARGQAYTEG
CCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
ELKAMMAAAGVRDLRRIPLDIPNGAGVIAGTVA
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1548230 [H]