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The map label for this gene is htpX1 [H]

Identifier: 39996291

GI number: 39996291

Start: 1294633

End: 1295583

Strand: Reverse

Name: htpX1 [H]

Synonym: GSU1189

Alternate gene names: 39996291

Gene position: 1295583-1294633 (Counterclockwise)

Preceding gene: 39996292

Following gene: 39996288

Centisome position: 33.97

GC content: 63.51

Gene sequence:

>951_bases
ATGCTGGCCCAGAGGTTGCGCAACCTCATCCAGTCCATGGTGCTCGTCACGGGCATGGTGGGGCTTCTTCTCACCCTCGG
CTGGCTCTTTGCCGGCATCTATGGCATGGCATGGGCACTACTGGTCGGAATCATCCCGCTGGTGGTGAGTCTGAGGGTCC
TTCCCGCTCTCATCCTCAGGATGTACAAGGCAAAGGCCCTCTCCGTCGCCGAAGCCCCCCAACTTCACGCTATCGTTAAC
CAGCTTGCCCGCCGCGCCGGCCTGGCGGAGCCCCCCCGCATCCACTATATTCCCAGTTCCGCCCCCCTGGTCTTCTCAAT
CGGCAGCGGCAAGGGAGCCTCAGTGGCCGTAACCGACGGCCTGCTGCGGCTTCTGACCGTCCGGGAGCTTGTCGGCGTTC
TGGGACACGAGGTCAGTCACATCGGCAACAGCGACACCTGGGTCATGAGCTTCGCCGACGTGGTGACCCGCGTGACCCGC
CTCATCTCGCTACTGGGACAGGTACTGATCATCCTCAACCTTCCCCTGCTGATCCTGGGGGAGTGGTCTCTGCCGTGGAT
CCCGCTGATGCTCATGCTCTTTGCCCCCACCATCAGCGCCCTGCTCCAGCTTTCTCTCTCGCGGACCCGCGAGTTCGAGG
CGGACCTCTCCGGCTCAAAGCTCACCAGTGACCCGGCGGGGCTCGCCTCGGCCCTGGCCAAGCTGGAGGAGTATCAGCAG
AGAGTCCTGAAAAAAAGCCGGCTACCGGGCGTGAAGGGAATCGAGCCGTCCCTGCTCAGGACTCATCCCGTAACCGATGA
ACGAATCAAAAGGCTGAAAGATATTGAGCGGGAGATGTACCCGGACGAGAGCATGCTGGTCTGCCCCGAAGACGGCGGGC
CGTGCGCCCCACCCCACATCGCGGAAGTGAGCCGCGTGCCGCGTCGCCACCTGAGCGGCCTGTGGCACTGA

Upstream 100 bases:

>100_bases
TGGGTGGAGGATGCCGTCATTTCCCTGGAGGATTTTTCCTCAGGAGAGCGGGAGCTGAACACGTTCCTCGCCTCGCGCAG
ACAGGCCGCGGTGTAGAGCC

Downstream 100 bases:

>100_bases
GTCCGGAATCAGTCTCACCCTCTGAAGGTGTAGTAGACGCTCAGAAAACCGAGTAGAAGCGATACGGCCGTGGCCAGGGC
GCAGGCACCTGCCAGGAAGG

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLAQRLRNLIQSMVLVTGMVGLLLTLGWLFAGIYGMAWALLVGIIPLVVSLRVLPALILRMYKAKALSVAEAPQLHAIVN
QLARRAGLAEPPRIHYIPSSAPLVFSIGSGKGASVAVTDGLLRLLTVRELVGVLGHEVSHIGNSDTWVMSFADVVTRVTR
LISLLGQVLIILNLPLLILGEWSLPWIPLMLMLFAPTISALLQLSLSRTREFEADLSGSKLTSDPAGLASALAKLEEYQQ
RVLKKSRLPGVKGIEPSLLRTHPVTDERIKRLKDIEREMYPDESMLVCPEDGGPCAPPHIAEVSRVPRRHLSGLWH

Sequences:

>Translated_316_residues
MLAQRLRNLIQSMVLVTGMVGLLLTLGWLFAGIYGMAWALLVGIIPLVVSLRVLPALILRMYKAKALSVAEAPQLHAIVN
QLARRAGLAEPPRIHYIPSSAPLVFSIGSGKGASVAVTDGLLRLLTVRELVGVLGHEVSHIGNSDTWVMSFADVVTRVTR
LISLLGQVLIILNLPLLILGEWSLPWIPLMLMLFAPTISALLQLSLSRTREFEADLSGSKLTSDPAGLASALAKLEEYQQ
RVLKKSRLPGVKGIEPSLLRTHPVTDERIKRLKDIEREMYPDESMLVCPEDGGPCAPPHIAEVSRVPRRHLSGLWH
>Mature_316_residues
MLAQRLRNLIQSMVLVTGMVGLLLTLGWLFAGIYGMAWALLVGIIPLVVSLRVLPALILRMYKAKALSVAEAPQLHAIVN
QLARRAGLAEPPRIHYIPSSAPLVFSIGSGKGASVAVTDGLLRLLTVRELVGVLGHEVSHIGNSDTWVMSFADVVTRVTR
LISLLGQVLIILNLPLLILGEWSLPWIPLMLMLFAPTISALLQLSLSRTREFEADLSGSKLTSDPAGLASALAKLEEYQQ
RVLKKSRLPGVKGIEPSLLRTHPVTDERIKRLKDIEREMYPDESMLVCPEDGGPCAPPHIAEVSRVPRRHLSGLWH

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 34584; Mature: 34584

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQRLRNLIQSMVLVTGMVGLLLTLGWLFAGIYGMAWALLVGIIPLVVSLRVLPALILR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYKAKALSVAEAPQLHAIVNQLARRAGLAEPPRIHYIPSSAPLVFSIGSGKGASVAVTDG
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCCCCEEHHHHH
LLRLLTVRELVGVLGHEVSHIGNSDTWVMSFADVVTRVTRLISLLGQVLIILNLPLLILG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEC
EWSLPWIPLMLMLFAPTISALLQLSLSRTREFEADLSGSKLTSDPAGLASALAKLEEYQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RVLKKSRLPGVKGIEPSLLRTHPVTDERIKRLKDIEREMYPDESMLVCPEDGGPCAPPHI
HHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
AEVSRVPRRHLSGLWH
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLAQRLRNLIQSMVLVTGMVGLLLTLGWLFAGIYGMAWALLVGIIPLVVSLRVLPALILR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYKAKALSVAEAPQLHAIVNQLARRAGLAEPPRIHYIPSSAPLVFSIGSGKGASVAVTDG
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCCCCEEHHHHH
LLRLLTVRELVGVLGHEVSHIGNSDTWVMSFADVVTRVTRLISLLGQVLIILNLPLLILG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEC
EWSLPWIPLMLMLFAPTISALLQLSLSRTREFEADLSGSKLTSDPAGLASALAKLEEYQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RVLKKSRLPGVKGIEPSLLRTHPVTDERIKRLKDIEREMYPDESMLVCPEDGGPCAPPHI
HHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
AEVSRVPRRHLSGLWH
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]