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The map label for this gene is mviN [H]

Identifier: 39996274

GI number: 39996274

Start: 1276965

End: 1278530

Strand: Direct

Name: mviN [H]

Synonym: GSU1172

Alternate gene names: 39996274

Gene position: 1276965-1278530 (Clockwise)

Preceding gene: 308513297

Following gene: 39996275

Centisome position: 33.48

GC content: 62.01

Gene sequence:

>1566_bases
ATGTCTGAAAAGAAGCAGATAGCCCGGGCTGCCGGCGTCCTCGGCCTGGCAACCATCGTCTCCCGCATCATGGGGATGGT
GCGCGACATGGCCGTCTCCCGTTTTTTTGGCGCCGGCCTCCAGACCGACGCCTTCTTCGCTGCCTTCCAGATTCCCAATA
TGCTGCGCCGGTTTTTCGCCGAGGGTGCCCTTACGTCGGCATTCGTGCCGACCTTCTCCGAGTGGCACTCCCAGCGAAGC
CCCGAGGAGGCGCGCGAGCTCGCCAACGTGTGCTTCACGCTTCTCACCATTGTCATGGCGGGCGTGACCCTGGCGGGGGT
CCTGCTCGCTCCCGGCATCGTCTCGGTCATGTTTCCCGGTTTCAGGGCCGACCCGACCAAGTTCGGGCTCACGGTCTTTC
TCAACCGGCTCATGTTCCCGTATATTTTCTTCATAAGCCTGCTGGCGCTCTGCATGGGGATACTCAATACGGTTCGCCAC
TTTTTCACCCCGGCCATCTCCACCGTGTTTCTGAACGTTTCCATGATTCTCTGTGCCTGGCTGCTTCGAGACCGGTTCGC
GGTGCCGATCACTGCCTTGGCCGTGGGGGTCCTTATGGGTGGGGTCCTTCAGCTCCTCCTTCAGGTGCCGGTGCTCTACC
GCAAGGGATTCCCGCTTCGCGTCCGTTTCGATCTCCACCATCCCGCGGTACGGCGCATCGCCCTTCTCATGGGGCCGTCG
GTTTTCGGGGTTGGGGTCTACTACCTGAACATCACTGTGGGCAATATTCTTGCTTCGCTCCTTCCCGAGGGAAGCGTCTC
GTACCTCTACTACGCCCAGCGACTGTTCGAGTTCCCTCAGGGGATCTTCACCGTTTCCGTGGCCCAGGCGGTTCTGCCGT
CACTGAGCCGGCAGGCGGCGGCCGGCGACATGGATGCCTTCCGGGAGTCTCTCGTCTTCGGCCTGCGGCTCACCCTGTTC
GTTACCATTCCGGCCACGGTGGGCCTTATGGTCTGCGCTACCCCCATTTTCAGCCTCCTCTTCATGGGGGGGGAGTTCGA
CTACGCCCAAGCCGCCAATGCGGGAATAGCCCTGTTCTACTACGCCATTGGACTTTCGCTCGTGGCCTTGGTGCGGGTTC
TGGTGCCCGCGTTTTACGCTCTCAAGGATACGAGGACGCCGGTCATGGTCGCCTTCGTCGCCTTCATCATGAACGCCGTT
GCCAGCCTCATCCTCATGAAACCTCTCGCCCATGGCGGATTGGCCCTGGCGTCCTCCCTGTCCGCCCTTGCCAACATGGG
GCTCCTTCTGGTCCTCCTGCGGCGGAAGATCGGTCCGTTCGGCGGGAGGGCTTTGGTCCGTTCAGGCATGAAGGTTCTCG
CGGCATCCCTGCCCATGGCGCTGGCGGTCCGTTGGATGGTGGCGCTCATCGATTGGTCACTGCCAGGGGAAAAGATGCTT
AAGGGGGGAGTTCTGCTCGGCGCCGTGGGCGTGGGCATCGTGTTGTTTCTTGCAGCCGCCGCGTTGCTCCGCAGCGAAGA
GACGCGCGAGCTGGCGGCACAACTCAGAAGGAGGTTTGCTCGATGA

Upstream 100 bases:

>100_bases
TAATCCGGCCGGTCCGACCGGGGTGAGTCACTGAAAAAGCTCCCAAATACCCGGCGACTGTGGTACATACCTCCCCTGAT
CACATTCTCCAGGGGAGCCC

Downstream 100 bases:

>100_bases
CGGGAACAGCGGCGCGCGACGAGGTGTATGTGTCCTTTTTCGAGACGGCGGTGGGGGTCGGTGCCGTGGTGGCGGGCAGC
GGGGGACTCAGGGAGGTGTT

Product: virulence factor mviN protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSEKKQIARAAGVLGLATIVSRIMGMVRDMAVSRFFGAGLQTDAFFAAFQIPNMLRRFFAEGALTSAFVPTFSEWHSQRS
PEEARELANVCFTLLTIVMAGVTLAGVLLAPGIVSVMFPGFRADPTKFGLTVFLNRLMFPYIFFISLLALCMGILNTVRH
FFTPAISTVFLNVSMILCAWLLRDRFAVPITALAVGVLMGGVLQLLLQVPVLYRKGFPLRVRFDLHHPAVRRIALLMGPS
VFGVGVYYLNITVGNILASLLPEGSVSYLYYAQRLFEFPQGIFTVSVAQAVLPSLSRQAAAGDMDAFRESLVFGLRLTLF
VTIPATVGLMVCATPIFSLLFMGGEFDYAQAANAGIALFYYAIGLSLVALVRVLVPAFYALKDTRTPVMVAFVAFIMNAV
ASLILMKPLAHGGLALASSLSALANMGLLLVLLRRKIGPFGGRALVRSGMKVLAASLPMALAVRWMVALIDWSLPGEKML
KGGVLLGAVGVGIVLFLAAAALLRSEETRELAAQLRRRFAR

Sequences:

>Translated_521_residues
MSEKKQIARAAGVLGLATIVSRIMGMVRDMAVSRFFGAGLQTDAFFAAFQIPNMLRRFFAEGALTSAFVPTFSEWHSQRS
PEEARELANVCFTLLTIVMAGVTLAGVLLAPGIVSVMFPGFRADPTKFGLTVFLNRLMFPYIFFISLLALCMGILNTVRH
FFTPAISTVFLNVSMILCAWLLRDRFAVPITALAVGVLMGGVLQLLLQVPVLYRKGFPLRVRFDLHHPAVRRIALLMGPS
VFGVGVYYLNITVGNILASLLPEGSVSYLYYAQRLFEFPQGIFTVSVAQAVLPSLSRQAAAGDMDAFRESLVFGLRLTLF
VTIPATVGLMVCATPIFSLLFMGGEFDYAQAANAGIALFYYAIGLSLVALVRVLVPAFYALKDTRTPVMVAFVAFIMNAV
ASLILMKPLAHGGLALASSLSALANMGLLLVLLRRKIGPFGGRALVRSGMKVLAASLPMALAVRWMVALIDWSLPGEKML
KGGVLLGAVGVGIVLFLAAAALLRSEETRELAAQLRRRFAR
>Mature_520_residues
SEKKQIARAAGVLGLATIVSRIMGMVRDMAVSRFFGAGLQTDAFFAAFQIPNMLRRFFAEGALTSAFVPTFSEWHSQRSP
EEARELANVCFTLLTIVMAGVTLAGVLLAPGIVSVMFPGFRADPTKFGLTVFLNRLMFPYIFFISLLALCMGILNTVRHF
FTPAISTVFLNVSMILCAWLLRDRFAVPITALAVGVLMGGVLQLLLQVPVLYRKGFPLRVRFDLHHPAVRRIALLMGPSV
FGVGVYYLNITVGNILASLLPEGSVSYLYYAQRLFEFPQGIFTVSVAQAVLPSLSRQAAAGDMDAFRESLVFGLRLTLFV
TIPATVGLMVCATPIFSLLFMGGEFDYAQAANAGIALFYYAIGLSLVALVRVLVPAFYALKDTRTPVMVAFVAFIMNAVA
SLILMKPLAHGGLALASSLSALANMGLLLVLLRRKIGPFGGRALVRSGMKVLAASLPMALAVRWMVALIDWSLPGEKMLK
GGVLLGAVGVGIVLFLAAAALLRSEETRELAAQLRRRFAR

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=419, Percent_Identity=41.2887828162291, Blast_Score=314, Evalue=1e-86,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 56407; Mature: 56275

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKQIARAAGVLGLATIVSRIMGMVRDMAVSRFFGAGLQTDAFFAAFQIPNMLRRFFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGALTSAFVPTFSEWHSQRSPEEARELANVCFTLLTIVMAGVTLAGVLLAPGIVSVMFPG
HCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FRADPTKFGLTVFLNRLMFPYIFFISLLALCMGILNTVRHFFTPAISTVFLNVSMILCAW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRDRFAVPITALAVGVLMGGVLQLLLQVPVLYRKGFPLRVRFDLHHPAVRRIALLMGPS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCH
VFGVGVYYLNITVGNILASLLPEGSVSYLYYAQRLFEFPQGIFTVSVAQAVLPSLSRQAA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AGDMDAFRESLVFGLRLTLFVTIPATVGLMVCATPIFSLLFMGGEFDYAQAANAGIALFY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
YAIGLSLVALVRVLVPAFYALKDTRTPVMVAFVAFIMNAVASLILMKPLAHGGLALASSL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SALANMGLLLVLLRRKIGPFGGRALVRSGMKVLAASLPMALAVRWMVALIDWSLPGEKML
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KGGVLLGAVGVGIVLFLAAAALLRSEETRELAAQLRRRFAR
HCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEKKQIARAAGVLGLATIVSRIMGMVRDMAVSRFFGAGLQTDAFFAAFQIPNMLRRFFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGALTSAFVPTFSEWHSQRSPEEARELANVCFTLLTIVMAGVTLAGVLLAPGIVSVMFPG
HCCHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FRADPTKFGLTVFLNRLMFPYIFFISLLALCMGILNTVRHFFTPAISTVFLNVSMILCAW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRDRFAVPITALAVGVLMGGVLQLLLQVPVLYRKGFPLRVRFDLHHPAVRRIALLMGPS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCH
VFGVGVYYLNITVGNILASLLPEGSVSYLYYAQRLFEFPQGIFTVSVAQAVLPSLSRQAA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AGDMDAFRESLVFGLRLTLFVTIPATVGLMVCATPIFSLLFMGGEFDYAQAANAGIALFY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
YAIGLSLVALVRVLVPAFYALKDTRTPVMVAFVAFIMNAVASLILMKPLAHGGLALASSL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SALANMGLLLVLLRRKIGPFGGRALVRSGMKVLAASLPMALAVRWMVALIDWSLPGEKML
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KGGVLLGAVGVGIVLFLAAAALLRSEETRELAAQLRRRFAR
HCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]