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The map label for this gene is nlpI [C]

Identifier: 39996268

GI number: 39996268

Start: 1271943

End: 1272743

Strand: Direct

Name: nlpI [C]

Synonym: GSU1166

Alternate gene names: 39996268

Gene position: 1271943-1272743 (Clockwise)

Preceding gene: 39996266

Following gene: 39996269

Centisome position: 33.35

GC content: 63.17

Gene sequence:

>801_bases
ATGACCGAAACGAACAATGAACTGTTGGCAAAAGGCATAAGCCTCGCCGAAGGGGGCGATTTCACCGCCGCCGAAGCGAT
GTTCAGAACCTGCGTGGAGAGGGCTCCCGATGACCCCGAAGGCTACTTCTACCTGGGAGAAGCCCTCGTGGAAGAGGGCA
AGCTCGCAGAGGCCCGACAGCAGTACGAGAAGGGGCTCGCCCTGGCCCCGGGAGACGTGGACGGCCAGATCGCCCTCGGC
GACATCTGTCTGGAGCTGGCTGAGCACGAGGCCGCCCTGGCCGCCTACCGGCGTGCCGTGGAACTCGACCCCCGCAATGC
CGACGGCTATGTCAACATCGGCCTCGTCTACAACTCCCTGGAGGAGACCAGCAAGGCGATCGAGGCTTTCGAGAAGGCCC
TGGAGATCGATCCGGCCAATGTCTTCGCCTACAACGGCCTGGGTGACGCCTGGTACGGGCTCGGCGAGCGGGAAAAGGCC
ATAGACGCCTTCCGCAAGGGCATCGAGCTCGACCCTACCGATGCGGCGGCCCACTTCAACCTCGGTGAACTCTACTACGA
TCTCGGCGAGACCGAGGAGGCCGAGAAGGAGTGCCTTGAGGCGGTCCGGCTCGATCCCGACTTCACCATGTCCTACCTCA
CCCTCGGCAGCCTCTATATGGATGACGAGAGGGTGAAGGACGCCATCAGGTATCTGGAGCTCTATCTGCAAAAGGAAAAA
TCGCCCCAGGCCCGAGAGACCGTGGACGAGGTCAAGGCCGTGCTGGAGGGGCTGCGCGCCGAGGTGGCCGGCAAACCCTG
A

Upstream 100 bases:

>100_bases
TTTAACACCTCGGAACCCGATAACGGGCTGAAAGGTGGCAACGTTCGATTCTTTCTGTTATAGTGTGCCCCGACGTATGA
CGCTATCCGGGGGTGAGAGC

Downstream 100 bases:

>100_bases
TTTTTTGCCCTCCCTCCTTTGAATCGCCGCAATGTGCGGTACCATTGAAGTAAAGATGGATGAACGAAAGGAGGGATCAG
GTCATGTCGGAAGAAAAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTETNNELLAKGISLAEGGDFTAAEAMFRTCVERAPDDPEGYFYLGEALVEEGKLAEARQQYEKGLALAPGDVDGQIALG
DICLELAEHEAALAAYRRAVELDPRNADGYVNIGLVYNSLEETSKAIEAFEKALEIDPANVFAYNGLGDAWYGLGEREKA
IDAFRKGIELDPTDAAAHFNLGELYYDLGETEEAEKECLEAVRLDPDFTMSYLTLGSLYMDDERVKDAIRYLELYLQKEK
SPQARETVDEVKAVLEGLRAEVAGKP

Sequences:

>Translated_266_residues
MTETNNELLAKGISLAEGGDFTAAEAMFRTCVERAPDDPEGYFYLGEALVEEGKLAEARQQYEKGLALAPGDVDGQIALG
DICLELAEHEAALAAYRRAVELDPRNADGYVNIGLVYNSLEETSKAIEAFEKALEIDPANVFAYNGLGDAWYGLGEREKA
IDAFRKGIELDPTDAAAHFNLGELYYDLGETEEAEKECLEAVRLDPDFTMSYLTLGSLYMDDERVKDAIRYLELYLQKEK
SPQARETVDEVKAVLEGLRAEVAGKP
>Mature_265_residues
TETNNELLAKGISLAEGGDFTAAEAMFRTCVERAPDDPEGYFYLGEALVEEGKLAEARQQYEKGLALAPGDVDGQIALGD
ICLELAEHEAALAAYRRAVELDPRNADGYVNIGLVYNSLEETSKAIEAFEKALEIDPANVFAYNGLGDAWYGLGEREKAI
DAFRKGIELDPTDAAAHFNLGELYYDLGETEEAEKECLEAVRLDPDFTMSYLTLGSLYMDDERVKDAIRYLELYLQKEKS
PQARETVDEVKAVLEGLRAEVAGKP

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=254, Percent_Identity=27.9527559055118, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI32307150, Length=254, Percent_Identity=27.9527559055118, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI224809432, Length=207, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI301336134, Length=222, Percent_Identity=26.5765765765766, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI83415184, Length=223, Percent_Identity=26.457399103139, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI167466177, Length=183, Percent_Identity=24.0437158469945, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI118766330, Length=236, Percent_Identity=26.6949152542373, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI167466175, Length=183, Percent_Identity=24.0437158469945, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI118766328, Length=236, Percent_Identity=26.6949152542373, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22749211, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI310110582, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI310123097, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI310131789, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=256, Percent_Identity=27.734375, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI115532692, Length=256, Percent_Identity=27.734375, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25147174, Length=191, Percent_Identity=24.6073298429319, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319387, Length=222, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321960, Length=219, Percent_Identity=25.5707762557078, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647755, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24585827, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24585829, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI161076610, Length=231, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19920486, Length=231, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24656717, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18110006, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364285, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581187, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24659892, Length=158, Percent_Identity=24.0506329113924, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647123, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 29325; Mature: 29194

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETNNELLAKGISLAEGGDFTAAEAMFRTCVERAPDDPEGYFYLGEALVEEGKLAEARQ
CCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCHHHHHH
QYEKGLALAPGDVDGQIALGDICLELAEHEAALAAYRRAVELDPRNADGYVNIGLVYNSL
HHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHH
EETSKAIEAFEKALEIDPANVFAYNGLGDAWYGLGEREKAIDAFRKGIELDPTDAAAHFN
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCC
LGELYYDLGETEEAEKECLEAVRLDPDFTMSYLTLGSLYMDDERVKDAIRYLELYLQKEK
HHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
SPQARETVDEVKAVLEGLRAEVAGKP
CCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TETNNELLAKGISLAEGGDFTAAEAMFRTCVERAPDDPEGYFYLGEALVEEGKLAEARQ
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCHHHHHH
QYEKGLALAPGDVDGQIALGDICLELAEHEAALAAYRRAVELDPRNADGYVNIGLVYNSL
HHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHH
EETSKAIEAFEKALEIDPANVFAYNGLGDAWYGLGEREKAIDAFRKGIELDPTDAAAHFN
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCC
LGELYYDLGETEEAEKECLEAVRLDPDFTMSYLTLGSLYMDDERVKDAIRYLELYLQKEK
HHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
SPQARETVDEVKAVLEGLRAEVAGKP
CCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]