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The map label for this gene is macB [H]

Identifier: 39996266

GI number: 39996266

Start: 1268258

End: 1269421

Strand: Direct

Name: macB [H]

Synonym: GSU1164

Alternate gene names: 39996266

Gene position: 1268258-1269421 (Clockwise)

Preceding gene: 39996265

Following gene: 39996268

Centisome position: 33.25

GC content: 63.32

Gene sequence:

>1164_bases
GTGGGAATCCCTTACTCTTACAGCCTGCGCAATCTCTGGACCCGGCGCCTCACTACCGTGCTGACGGCATCGGGCATGGC
GCTGGTGGTCTTCGTGTTCGCGGCGACTCTTATGCTCTCCGAGGGCCTGCGCAAGACCCTGGTGGACACCGGCTCGTGGG
ACAACGTGGTGGTGATCCGCAAGTCCGCCCAGACAGAGGTGCAGAGCGGGGTGGACCGATCCCAGGCGGCCATCGTGGAG
ACCCAGCCCGAGGTGGCGATGGCGGAAGGACAACGGTTGGTGGCCAAGGAGTTGGTTGTCCTCATCAGCCTGCCGAAGCG
GGGAACGGGAAAGCCGTCCAACGTGGTGATCCGTGGCATCGGCGCGCCATCGCTTCTGCTGAGACCCCAGGTGAAGCTTC
GGGAGGGGCGGATGCCCCGGCCCGGCTCGGCGGAGATTATCGCCGGGGCGAGCATCGCCAAGCGGTTCCAGGGGGGAGGG
ATCGGCGAAACCCTGCGCTTCGGCATGCGGGACTGGACCGTGGTGGGTATCTTCGATGCCGGCAACACGGGGTTTTCTTC
GGAGATATGGGGGGACGTTGATCAGCTGATGCAGGCCTTCCGGCGTCCGGTCTACTCGTCGGTCATCTTCAAACTCAGGG
ATGCCGCCGAGTTCGGTCGCGTCAAGGCCAGGCTGGAGGCGGACCCGCGCCTCACCGTGGAGGCAAAGCGCGAGATCCGC
TTCTATGCCGACCAATCGGAAGCCATGGCCACGTTCCTGAACATCCTGGGCGTTACACTGACGGTGATTTTTTCCCTGGG
CGCGGTCATCGGTGCCATGATCACCATGTATGCCGCCGTGGCCAACCGGATCACCGAGATCGGTACGTTGCGCGCACTCG
GTTTCCAGCGGCGAAGCATTCTGGGGGCGTTTATCCTGGAATCGCTGTTTCTGGGGTTGCTGGGAGGGGTGGTGGGGGTC
TTTTTCGCCTCGTTCATGCAGCTGGTGACCATCTCAACCATGAACTGGCAGACTTTTTCGGAGCTGGCGTTCAGCTTTAC
CCTTACCCCACGCATCATCGGGGCGTCGCTGGTGTTTTCCCTGGTCATGGGGTTCGTGGGGGGGCTGCTTCCGGCGTTCC
GGGCAGCGCGGATGAATATCGTGGACGCCCTGCGGGCGAACTGA

Upstream 100 bases:

>100_bases
ACCTGGCGGCAGCCTTCATCGTGGGGGCGGTGGCCGGCATCTTCCCCACCTGGCGCGGGGTGACCATCCGTATCGCCGAG
GGTCTCAGGAGAGTCGGATA

Downstream 100 bases:

>100_bases
AGGGGGAGTTCAGAGGCCGAGCCGCGCCCGTGCGTCGAGCAGATAGGCCCTTACTGCGCCGGAGCTTTCCAGGGCCAGTA
CTTCCCGCGCCACTTCTTCG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MGIPYSYSLRNLWTRRLTTVLTASGMALVVFVFAATLMLSEGLRKTLVDTGSWDNVVVIRKSAQTEVQSGVDRSQAAIVE
TQPEVAMAEGQRLVAKELVVLISLPKRGTGKPSNVVIRGIGAPSLLLRPQVKLREGRMPRPGSAEIIAGASIAKRFQGGG
IGETLRFGMRDWTVVGIFDAGNTGFSSEIWGDVDQLMQAFRRPVYSSVIFKLRDAAEFGRVKARLEADPRLTVEAKREIR
FYADQSEAMATFLNILGVTLTVIFSLGAVIGAMITMYAAVANRITEIGTLRALGFQRRSILGAFILESLFLGLLGGVVGV
FFASFMQLVTISTMNWQTFSELAFSFTLTPRIIGASLVFSLVMGFVGGLLPAFRAARMNIVDALRAN

Sequences:

>Translated_387_residues
MGIPYSYSLRNLWTRRLTTVLTASGMALVVFVFAATLMLSEGLRKTLVDTGSWDNVVVIRKSAQTEVQSGVDRSQAAIVE
TQPEVAMAEGQRLVAKELVVLISLPKRGTGKPSNVVIRGIGAPSLLLRPQVKLREGRMPRPGSAEIIAGASIAKRFQGGG
IGETLRFGMRDWTVVGIFDAGNTGFSSEIWGDVDQLMQAFRRPVYSSVIFKLRDAAEFGRVKARLEADPRLTVEAKREIR
FYADQSEAMATFLNILGVTLTVIFSLGAVIGAMITMYAAVANRITEIGTLRALGFQRRSILGAFILESLFLGLLGGVVGV
FFASFMQLVTISTMNWQTFSELAFSFTLTPRIIGASLVFSLVMGFVGGLLPAFRAARMNIVDALRAN
>Mature_386_residues
GIPYSYSLRNLWTRRLTTVLTASGMALVVFVFAATLMLSEGLRKTLVDTGSWDNVVVIRKSAQTEVQSGVDRSQAAIVET
QPEVAMAEGQRLVAKELVVLISLPKRGTGKPSNVVIRGIGAPSLLLRPQVKLREGRMPRPGSAEIIAGASIAKRFQGGGI
GETLRFGMRDWTVVGIFDAGNTGFSSEIWGDVDQLMQAFRRPVYSSVIFKLRDAAEFGRVKARLEADPRLTVEAKREIRF
YADQSEAMATFLNILGVTLTVIFSLGAVIGAMITMYAAVANRITEIGTLRALGFQRRSILGAFILESLFLGLLGGVVGVF
FASFMQLVTISTMNWQTFSELAFSFTLTPRIIGASLVFSLVMGFVGGLLPAFRAARMNIVDALRAN

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42058; Mature: 41927

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPYSYSLRNLWTRRLTTVLTASGMALVVFVFAATLMLSEGLRKTLVDTGSWDNVVVIR
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KSAQTEVQSGVDRSQAAIVETQPEVAMAEGQRLVAKELVVLISLPKRGTGKPSNVVIRGI
CCHHHHHHHCCCHHHHEEEECCCCHHHHCCHHHHHHHHHHHEECCCCCCCCCCCEEEEEC
GAPSLLLRPQVKLREGRMPRPGSAEIIAGASIAKRFQGGGIGETLRFGMRDWTVVGIFDA
CCCCHHCCCCHHHHCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEC
GNTGFSSEIWGDVDQLMQAFRRPVYSSVIFKLRDAAEFGRVKARLEADPRLTVEAKREIR
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
FYADQSEAMATFLNILGVTLTVIFSLGAVIGAMITMYAAVANRITEIGTLRALGFQRRSI
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAFILESLFLGLLGGVVGVFFASFMQLVTISTMNWQTFSELAFSFTLTPRIIGASLVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LVMGFVGGLLPAFRAARMNIVDALRAN
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIPYSYSLRNLWTRRLTTVLTASGMALVVFVFAATLMLSEGLRKTLVDTGSWDNVVVIR
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KSAQTEVQSGVDRSQAAIVETQPEVAMAEGQRLVAKELVVLISLPKRGTGKPSNVVIRGI
CCHHHHHHHCCCHHHHEEEECCCCHHHHCCHHHHHHHHHHHEECCCCCCCCCCCEEEEEC
GAPSLLLRPQVKLREGRMPRPGSAEIIAGASIAKRFQGGGIGETLRFGMRDWTVVGIFDA
CCCCHHCCCCHHHHCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEC
GNTGFSSEIWGDVDQLMQAFRRPVYSSVIFKLRDAAEFGRVKARLEADPRLTVEAKREIR
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
FYADQSEAMATFLNILGVTLTVIFSLGAVIGAMITMYAAVANRITEIGTLRALGFQRRSI
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAFILESLFLGLLGGVVGVFFASFMQLVTISTMNWQTFSELAFSFTLTPRIIGASLVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LVMGFVGGLLPAFRAARMNIVDALRAN
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA