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The map label for this gene is pfpI [H]

Identifier: 39996261

GI number: 39996261

Start: 1264180

End: 1264683

Strand: Direct

Name: pfpI [H]

Synonym: GSU1159

Alternate gene names: 39996261

Gene position: 1264180-1264683 (Clockwise)

Preceding gene: 39996260

Following gene: 39996262

Centisome position: 33.14

GC content: 64.48

Gene sequence:

>504_bases
ATGAAAGGACTCATCATCAGTGCCGACCAGTTCGAGGATTCTGAACTTCTCATCCCCTACTACCGCCTGCTGGAAGAGGG
GATTCCGGTCCGGATCGCGGCCCCGGCCCGCGGCACCATCACGGGCAAGCACGGCTATGCGGTGACAGCTGACCTGGCGC
TTGCCGAGGTCGCTGCCGACGACTACACCATCCTCATTCTGCCGGGGGGAAAAGCACCTGCTGCCGTGAGGCGGGAGCCG
GCGGCCCTGGAGATATGCCGGAGTTTCTTTGCCCATGTCAGGCCGGTAGCCGCCATCTGTCACGGTCCCCAGACGCTGGT
CAGCGCCGGACTCCTGTCGGGCAGGCGCGCCACCTGCTACCGCTCGGTGGCCGATGAGCTGCGCGGCGCGGGCGCCCTCT
ACGAGGATAGTGAAGTGGTGGTGGACGGCAACCTGATCACCTCCCGCGAGCCGGCGGATCTTCCGGCCTTCATGCGGGAG
ATAATGAAAAAGCTGAAGGGATAG

Upstream 100 bases:

>100_bases
TTCAGATCGGACACAGGGGGCGCTTACGGCGCCCCCTTTTTTCTTCCGGCAATCGGGAGCGTGCCGACCGGCCGCGGCGG
GACCACAGGAGGTGACAGCC

Downstream 100 bases:

>100_bases
GGGGGCGCGACATGAAACGGCTTCTGCTGATTGTCATGGTCTTATTCGTGGGAGTGGTGCCTGCCCTGGGAAACGGCGCG
GGTGAAAAGGTGGAATTCCG

Product: substrate-binding protein/sensor histidine kinase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKGLIISADQFEDSELLIPYYRLLEEGIPVRIAAPARGTITGKHGYAVTADLALAEVAADDYTILILPGGKAPAAVRREP
AALEICRSFFAHVRPVAAICHGPQTLVSAGLLSGRRATCYRSVADELRGAGALYEDSEVVVDGNLITSREPADLPAFMRE
IMKKLKG

Sequences:

>Translated_167_residues
MKGLIISADQFEDSELLIPYYRLLEEGIPVRIAAPARGTITGKHGYAVTADLALAEVAADDYTILILPGGKAPAAVRREP
AALEICRSFFAHVRPVAAICHGPQTLVSAGLLSGRRATCYRSVADELRGAGALYEDSEVVVDGNLITSREPADLPAFMRE
IMKKLKG
>Mature_167_residues
MKGLIISADQFEDSELLIPYYRLLEEGIPVRIAAPARGTITGKHGYAVTADLALAEVAADDYTILILPGGKAPAAVRREP
AALEICRSFFAHVRPVAAICHGPQTLVSAGLLSGRRATCYRSVADELRGAGALYEDSEVVVDGNLITSREPADLPAFMRE
IMKKLKG

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=164, Percent_Identity=40.8536585365854, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17558714, Length=164, Percent_Identity=26.219512195122, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571932, Length=166, Percent_Identity=32.5301204819277, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 17892; Mature: 17892

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLIISADQFEDSELLIPYYRLLEEGIPVRIAAPARGTITGKHGYAVTADLALAEVAAD
CCCEEECCCCCCCCCEEHHHHHHHHCCCCEEEECCCCCCEECCCCCEEEHHHHHHHHCCC
DYTILILPGGKAPAAVRREPAALEICRSFFAHVRPVAAICHGPQTLVSAGLLSGRRATCY
CEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
RSVADELRGAGALYEDSEVVVDGNLITSREPADLPAFMREIMKKLKG
HHHHHHHHCCCCCCCCCEEEEECCEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKGLIISADQFEDSELLIPYYRLLEEGIPVRIAAPARGTITGKHGYAVTADLALAEVAAD
CCCEEECCCCCCCCCEEHHHHHHHHCCCCEEEECCCCCCEECCCCCEEEHHHHHHHHCCC
DYTILILPGGKAPAAVRREPAALEICRSFFAHVRPVAAICHGPQTLVSAGLLSGRRATCY
CEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
RSVADELRGAGALYEDSEVVVDGNLITSREPADLPAFMREIMKKLKG
HHHHHHHHCCCCCCCCCEEEEECCEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]