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The map label for this gene is ycbL [H]

Identifier: 39996225

GI number: 39996225

Start: 1207667

End: 1208296

Strand: Direct

Name: ycbL [H]

Synonym: GSU1123

Alternate gene names: 39996225

Gene position: 1207667-1208296 (Clockwise)

Preceding gene: 39996224

Following gene: 39996226

Centisome position: 31.66

GC content: 63.17

Gene sequence:

>630_bases
ATGATCTTCGAAACCGTTGTCGTCGGCCCGCTGGGGGTTAATTGTTTCATTCTCGGCTGTGAGCAGAGCCGCGAAGGGGT
AATCGTGGACCCGGGAGCAGAGTCCGGGCGGATTCTCGAACGAGTCGGCGAACTGGGGCTCAAGGTTGGCATGGTGATAA
ACACCCACGGCCACTTTGATCACGTGGGGGGCAACCGGAAGGTGCTGGAAGCCACGGGGGCGAAGCTGCTGGTCCACCGG
GACGACGTCCACTTCCTCGACCGCGCCGCGGACGTTGCCGCCATGTATGGTCTCGATACGGAGAACTCACCGGCTCCCGA
CTCGCTTCTGGAGGACGGCATGACCCTTTCCGTGGGAACCCTTAGCCTCCGGGTCCTTCATACGCCCGGTCACACGCCGG
GGGGGTGCTGTCTGCTTCTGGAGGGGGAAGGAAAGGTGCTCACCGGTGACACCCTGTTCGAGGAATCGGTGGGGCGCACC
GATTTCCCAGGCTCCTCCCACGAGGCCCTCATCACGTCGATCCGCGAAAAACTCCTGACCCTGCCGGACGAGACTGAGGT
CTATCCGGGCCATGGTCCGGCAACGTCCATCGGCCGGGAGCGGCGGTACAACCCCTACCTGACGGATTAG

Upstream 100 bases:

>100_bases
GCAACACCGCCCGAAAGGGGTTCAGCAACAATCCGTTCGAGACCCTGCAAAAGAATCTGGATCTGTTCTGAGCATATATT
CCACGTAGAGAGGGTGTATC

Downstream 100 bases:

>100_bases
CGCGCACGCGGAAACCCTGGGAAACAGTGCGCGGCGGAGGCCCAATGCTCAAGGGAAAAGAGATCGTTCTCGGTATTTGC
GGCGGCATCGCAGTCTACAA

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIFETVVVGPLGVNCFILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFDHVGGNRKVLEATGAKLLVHR
DDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGTLSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRT
DFPGSSHEALITSIREKLLTLPDETEVYPGHGPATSIGRERRYNPYLTD

Sequences:

>Translated_209_residues
MIFETVVVGPLGVNCFILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFDHVGGNRKVLEATGAKLLVHR
DDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGTLSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRT
DFPGSSHEALITSIREKLLTLPDETEVYPGHGPATSIGRERRYNPYLTD
>Mature_209_residues
MIFETVVVGPLGVNCFILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFDHVGGNRKVLEATGAKLLVHR
DDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGTLSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRT
DFPGSSHEALITSIREKLLTLPDETEVYPGHGPATSIGRERRYNPYLTD

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=204, Percent_Identity=30.8823529411765, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI94538320, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI94538322, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1787158, Length=210, Percent_Identity=37.1428571428571, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17538952, Length=212, Percent_Identity=27.8301886792453, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320478, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330176, Length=213, Percent_Identity=30.5164319248826, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356335, Length=177, Percent_Identity=35.0282485875706, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667711, Length=177, Percent_Identity=35.0282485875706, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667703, Length=177, Percent_Identity=35.0282485875706, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 22386; Mature: 22386

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFETVVVGPLGVNCFILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFD
CEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHCCEEEEEEEECCCCEE
HVGGNRKVLEATGAKLLVHRDDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGT
CCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEEEE
LSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRTDFPGSSHEALITSIREKLLT
EEEEEEECCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
LPDETEVYPGHGPATSIGRERRYNPYLTD
CCCCCCEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIFETVVVGPLGVNCFILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFD
CEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHCCEEEEEEEECCCCEE
HVGGNRKVLEATGAKLLVHRDDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGT
CCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEEEE
LSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRTDFPGSSHEALITSIREKLLT
EEEEEEECCCCCCCCEEEEECCCCCEEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
LPDETEVYPGHGPATSIGRERRYNPYLTD
CCCCCCEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]