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The map label for this gene is regX3 [H]

Identifier: 39996204

GI number: 39996204

Start: 1187640

End: 1188317

Strand: Reverse

Name: regX3 [H]

Synonym: GSU1102

Alternate gene names: 39996204

Gene position: 1188317-1187640 (Counterclockwise)

Preceding gene: 39996209

Following gene: 39996203

Centisome position: 31.16

GC content: 59.73

Gene sequence:

>678_bases
ATGAAAACGATACTTATCATCGAAGACGAGCGCGACCTGGCCGATCTGGTGGCCTTCAACCTTGAAAAAGAAGGGTATCG
GACCCTCACGGCACTGGATGGCGCGAACGGCCTGGAATTGGCCCGCAGCCAGCCCCCCGACCTGATCCTGCTGGACCTGA
TGCTGCCGGGAATGATGGGGATGGAGGTCTGCAAAATCCTCAAGAAGTCGGAAAAGACCGCCCATATCCCGGTCATCATG
CTGACGGCACGCGGCGAGGAGATCGACCGTGTGGTCGGCTTCGAGGTCGGGGCCGACGACTACGTGGTAAAACCCTTCTC
TACCCGCGAGTTGCTGCTCAGGGTGAAAGCGGTGCTGCGCCGCTCCCTCCCCGACAAGCCGGAAGGAAAGGTCATCAATG
TCGGGCCGGTGACGATCGATACGGAGCGTCACATGGTGGCCGTGGAGGGAGATGATGTCACCCTGACCACGACCGAGTTC
AAACTTCTGCTGAACCTTGCCGAGCGGCTCGGTCGGGTCCAGAGCCGCGACCTCCTTCTCAAAAACGTGTGGGGATATAA
TTACGTGGGAGACACCCGCACGGTGGATACTCATATCACCCGCCTGCGGACGAAGCTGGGACAGGCCGGAGAGCTGATCA
AGACCGTCCGCGGCTTCGGCTACAAGATGGAGGAATAG

Upstream 100 bases:

>100_bases
TGTGGAAACGGGCTCCATCTCTAGTCTTTACAGGCATTTTTCACAGCTGTAACACAAATGCAATATTGTGACGCTACCCT
CGCACGAGGGAGAGACATTC

Downstream 100 bases:

>100_bases
TGAAGCTCACCATCCAGTGGAAGCTGATGGCTTCCTATCTATGTTTGCTCCTCTTTATCGGGGGAGCTTTTTTCGTCTAC
CTTAACCATACTCTCACCAC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTILIIEDERDLADLVAFNLEKEGYRTLTALDGANGLELARSQPPDLILLDLMLPGMMGMEVCKILKKSEKTAHIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRVKAVLRRSLPDKPEGKVINVGPVTIDTERHMVAVEGDDVTLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGQAGELIKTVRGFGYKMEE

Sequences:

>Translated_225_residues
MKTILIIEDERDLADLVAFNLEKEGYRTLTALDGANGLELARSQPPDLILLDLMLPGMMGMEVCKILKKSEKTAHIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRVKAVLRRSLPDKPEGKVINVGPVTIDTERHMVAVEGDDVTLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGQAGELIKTVRGFGYKMEE
>Mature_225_residues
MKTILIIEDERDLADLVAFNLEKEGYRTLTALDGANGLELARSQPPDLILLDLMLPGMMGMEVCKILKKSEKTAHIPVIM
LTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRVKAVLRRSLPDKPEGKVINVGPVTIDTERHMVAVEGDDVTLTTTEF
KLLLNLAERLGRVQSRDLLLKNVWGYNYVGDTRTVDTHITRLRTKLGQAGELIKTVRGFGYKMEE

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=45.0892857142857, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=40.625, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=40.5405405405405, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=39.1111111111111, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=38.5650224215247, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=40.948275862069, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=36.283185840708, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.5132743362832, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=32.034632034632, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=34.5454545454545, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=34.6153846153846, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=33.7777777777778, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25235; Mature: 25235

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILIIEDERDLADLVAFNLEKEGYRTLTALDGANGLELARSQPPDLILLDLMLPGMMG
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCEEEHHHHCCCHHH
MEVCKILKKSEKTAHIPVIMLTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRVKAVLR
HHHHHHHHHCCCCCCCCEEEEEECCCHHHHHCCEEECCCCEEECCCCHHHHHHHHHHHHH
RSLPDKPEGKVINVGPVTIDTERHMVAVEGDDVTLTTTEFKLLLNLAERLGRVQSRDLLL
HCCCCCCCCCEEEECCEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHCCHHHHHHHH
KNVWGYNYVGDTRTVDTHITRLRTKLGQAGELIKTVRGFGYKMEE
HHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTILIIEDERDLADLVAFNLEKEGYRTLTALDGANGLELARSQPPDLILLDLMLPGMMG
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHCCCCCCEEEHHHHCCCHHH
MEVCKILKKSEKTAHIPVIMLTARGEEIDRVVGFEVGADDYVVKPFSTRELLLRVKAVLR
HHHHHHHHHCCCCCCCCEEEEEECCCHHHHHCCEEECCCCEEECCCCHHHHHHHHHHHHH
RSLPDKPEGKVINVGPVTIDTERHMVAVEGDDVTLTTTEFKLLLNLAERLGRVQSRDLLL
HCCCCCCCCCEEEECCEEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHCCHHHHHHHH
KNVWGYNYVGDTRTVDTHITRLRTKLGQAGELIKTVRGFGYKMEE
HHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA