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The map label for this gene is resE [H]

Identifier: 39996203

GI number: 39996203

Start: 1185871

End: 1187484

Strand: Reverse

Name: resE [H]

Synonym: GSU1101

Alternate gene names: 39996203

Gene position: 1187484-1185871 (Counterclockwise)

Preceding gene: 39996204

Following gene: 39996202

Centisome position: 31.13

GC content: 64.13

Gene sequence:

>1614_bases
ATGGTTGCCGGCCGTGAGATCCGTGATATGCGGCGGGATGCGCCCGCAGTGGCAGCGGCCATTTCGCGCGAGACCCGGGC
ACGCGTGACGGTGATCCTTGAGGGGGGCGAGGTGGTGGCCGACTCTGACATCGCACCCCAATACCTGGGAACGCTGGAAA
ACCACGCGAACCGCCCCGAAGTCCGCCAGGCGCTGGAACAGGGAGGGGGCGCCGCGGTCCGCTATTCAGCTACCATCAAG
ACCCCCATGCTCTACGTGGCGACCGTGCTCAACACCACAACGGGAGAGCGCGGCGTGCTGCGCCTGTCGCTCCCTCTCAC
CGCGGTAGAAAAGGCAAAACAGAGCATCCGGACCCTGCTGGGGGCATCTCTTGTGGTATCGCTGGTGGTTGCGCTGCTCC
TGAGCTATCTACTCTCGCGGCTCACATCCCGCTCGCTGCGCACCATCACAACCCTGGCCACCCAACTGGGCCGGGGAGAC
TACGGCCGGCGGATTCCGGTCATCACCCGCGATGAAGTCGGCGAACTCGCCCGCGTCATGAATGAAATGGCTTCGCAGAT
CGAACGGAACCTGGCGCGGATCTCGGCGGAGAAAAACCGGCTCGACACCATCCTCCGCGGAATGGGCGAGGGGCTGATGG
TGAGCGATGCCGGGGGAACCGTGACTCTCGTGAACCCGGCTTTTCTTGAGCTCTTCGGCCTCACCCAGAGCGTGGAAGGG
AGACAGATCATCGAAATCGCCCGGTTCCCCGAGCTGCATGAAACGTTCAGGGCCGTGGTGTCGTCCCGCAGCGAACACGT
GGAGGAGATGACGCTTCCCCTGGGGGACGAAAAGCAGGTGCTGACCCACTGGGTGCCGCTCATGGAAGAGGACGAACTGC
GCGGCGTGGTGGCGGTGTTCCACGACATTTCGGACCTGAAACGGCTTGAGGTTGTCCGCCGCGACTTCGTGGCCAATGTA
TCCCACGAACTCAGGACGCCGGTGACGGTCATCAAGGGATATGCCGAGGCCCTGGCCGGCGGACTCGTGGAGGAAGACCC
GGAACGGGCCGGGCGTTTCCTTGAGATTATTTGCAGTCACTCGGAACGACTCGCCGATCTGATCCGCGATCTCCTCACCC
TTTCACAGCTGGAATCGGGAGGACTCCAGCTGGAGCTGACCCAGATCCACCTGGACCGTGCGGTCTCCCACGCGGCGGGG
CTGCTGGAGCAGAAGGCCGCACGGAAGGAGATCGTCATCGACATCTCGGCCCTGGCAGGCGCTCCACCGGTACTGGCCGA
CCCGGGACGGCTGGAGCAGGTCCTCATCAACCTCATGGACAATGCCCTCAAGTACACGCCGCCCGGAGGAACCATCACCC
TCAGTGCCGATGAGGCGGACGGGATGGTGAGGGTGTCGGTTCACGACACCGGCATCGGCATCCCCCCCAAGGACCTGCCG
CGCATCTTTGAGAGGTTCTACCGGGTGGATGCCGCCCGCAGCCGCGACGAGGGGGGGACCGGCCTCGGCCTTTCCATCGT
GAAGCACATCATCCAGCTCCACGGCGGAAGCATCACTGTCGAGAGCGAGCACGGCAAAGGCACAACCTTCCGGTTCACCC
TGCGCAAGACCTGA

Upstream 100 bases:

>100_bases
TATCGGGGGAGCTTTTTTCGTCTACCTTAACCATACTCTCACCACGCACCTCGCCCACGAGATCCAGGAGAATCTCAAGA
GCGAATCGCGGCTGGCGCGG

Downstream 100 bases:

>100_bases
CCTATACGCACTACCATCAAGGGGGGCGGCCAACAACCGTCCCCCTTTTTTGTATGCGGATCACCCCGGTTAGTTCTGAA
GCAATTCTGCAAAAGCGAAA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MVAGREIRDMRRDAPAVAAAISRETRARVTVILEGGEVVADSDIAPQYLGTLENHANRPEVRQALEQGGGAAVRYSATIK
TPMLYVATVLNTTTGERGVLRLSLPLTAVEKAKQSIRTLLGASLVVSLVVALLLSYLLSRLTSRSLRTITTLATQLGRGD
YGRRIPVITRDEVGELARVMNEMASQIERNLARISAEKNRLDTILRGMGEGLMVSDAGGTVTLVNPAFLELFGLTQSVEG
RQIIEIARFPELHETFRAVVSSRSEHVEEMTLPLGDEKQVLTHWVPLMEEDELRGVVAVFHDISDLKRLEVVRRDFVANV
SHELRTPVTVIKGYAEALAGGLVEEDPERAGRFLEIICSHSERLADLIRDLLTLSQLESGGLQLELTQIHLDRAVSHAAG
LLEQKAARKEIVIDISALAGAPPVLADPGRLEQVLINLMDNALKYTPPGGTITLSADEADGMVRVSVHDTGIGIPPKDLP
RIFERFYRVDAARSRDEGGTGLGLSIVKHIIQLHGGSITVESEHGKGTTFRFTLRKT

Sequences:

>Translated_537_residues
MVAGREIRDMRRDAPAVAAAISRETRARVTVILEGGEVVADSDIAPQYLGTLENHANRPEVRQALEQGGGAAVRYSATIK
TPMLYVATVLNTTTGERGVLRLSLPLTAVEKAKQSIRTLLGASLVVSLVVALLLSYLLSRLTSRSLRTITTLATQLGRGD
YGRRIPVITRDEVGELARVMNEMASQIERNLARISAEKNRLDTILRGMGEGLMVSDAGGTVTLVNPAFLELFGLTQSVEG
RQIIEIARFPELHETFRAVVSSRSEHVEEMTLPLGDEKQVLTHWVPLMEEDELRGVVAVFHDISDLKRLEVVRRDFVANV
SHELRTPVTVIKGYAEALAGGLVEEDPERAGRFLEIICSHSERLADLIRDLLTLSQLESGGLQLELTQIHLDRAVSHAAG
LLEQKAARKEIVIDISALAGAPPVLADPGRLEQVLINLMDNALKYTPPGGTITLSADEADGMVRVSVHDTGIGIPPKDLP
RIFERFYRVDAARSRDEGGTGLGLSIVKHIIQLHGGSITVESEHGKGTTFRFTLRKT
>Mature_537_residues
MVAGREIRDMRRDAPAVAAAISRETRARVTVILEGGEVVADSDIAPQYLGTLENHANRPEVRQALEQGGGAAVRYSATIK
TPMLYVATVLNTTTGERGVLRLSLPLTAVEKAKQSIRTLLGASLVVSLVVALLLSYLLSRLTSRSLRTITTLATQLGRGD
YGRRIPVITRDEVGELARVMNEMASQIERNLARISAEKNRLDTILRGMGEGLMVSDAGGTVTLVNPAFLELFGLTQSVEG
RQIIEIARFPELHETFRAVVSSRSEHVEEMTLPLGDEKQVLTHWVPLMEEDELRGVVAVFHDISDLKRLEVVRRDFVANV
SHELRTPVTVIKGYAEALAGGLVEEDPERAGRFLEIICSHSERLADLIRDLLTLSQLESGGLQLELTQIHLDRAVSHAAG
LLEQKAARKEIVIDISALAGAPPVLADPGRLEQVLINLMDNALKYTPPGGTITLSADEADGMVRVSVHDTGIGIPPKDLP
RIFERFYRVDAARSRDEGGTGLGLSIVKHIIQLHGGSITVESEHGKGTTFRFTLRKT

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=330, Percent_Identity=32.4242424242424, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=34.7826086956522, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=33.8709677419355, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=34.6153846153846, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=34.5132743362832, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=35.9447004608295, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=32.4, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788713, Length=308, Percent_Identity=28.8961038961039, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790861, Length=210, Percent_Identity=36.6666666666667, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=33.0357142857143, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788549, Length=380, Percent_Identity=28.1578947368421, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=32.15859030837, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=273, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788279, Length=236, Percent_Identity=28.3898305084746, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789403, Length=208, Percent_Identity=31.7307692307692, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=30.1255230125523, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=248, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789808, Length=255, Percent_Identity=27.843137254902, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58580; Mature: 58580

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAGREIRDMRRDAPAVAAAISRETRARVTVILEGGEVVADSDIAPQYLGTLENHANRPE
CCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCEEECCCCCHHHHHHHHHCCCCHH
VRQALEQGGGAAVRYSATIKTPMLYVATVLNTTTGERGVLRLSLPLTAVEKAKQSIRTLL
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
GASLVVSLVVALLLSYLLSRLTSRSLRTITTLATQLGRGDYGRRIPVITRDEVGELARVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHH
NEMASQIERNLARISAEKNRLDTILRGMGEGLMVSDAGGTVTLVNPAFLELFGLTQSVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHCCCCCCC
RQIIEIARFPELHETFRAVVSSRSEHVEEMTLPLGDEKQVLTHWVPLMEEDELRGVVAVF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
HDISDLKRLEVVRRDFVANVSHELRTPVTVIKGYAEALAGGLVEEDPERAGRFLEIICSH
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
SERLADLIRDLLTLSQLESGGLQLELTQIHLDRAVSHAAGLLEQKAARKEIVIDISALAG
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCC
APPVLADPGRLEQVLINLMDNALKYTPPGGTITLSADEADGMVRVSVHDTGIGIPPKDLP
CCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHH
RIFERFYRVDAARSRDEGGTGLGLSIVKHIIQLHGGSITVESEHGKGTTFRFTLRKT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MVAGREIRDMRRDAPAVAAAISRETRARVTVILEGGEVVADSDIAPQYLGTLENHANRPE
CCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCEEECCCCCHHHHHHHHHCCCCHH
VRQALEQGGGAAVRYSATIKTPMLYVATVLNTTTGERGVLRLSLPLTAVEKAKQSIRTLL
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
GASLVVSLVVALLLSYLLSRLTSRSLRTITTLATQLGRGDYGRRIPVITRDEVGELARVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHH
NEMASQIERNLARISAEKNRLDTILRGMGEGLMVSDAGGTVTLVNPAFLELFGLTQSVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHCCCCCCC
RQIIEIARFPELHETFRAVVSSRSEHVEEMTLPLGDEKQVLTHWVPLMEEDELRGVVAVF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
HDISDLKRLEVVRRDFVANVSHELRTPVTVIKGYAEALAGGLVEEDPERAGRFLEIICSH
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
SERLADLIRDLLTLSQLESGGLQLELTQIHLDRAVSHAAGLLEQKAARKEIVIDISALAG
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHCC
APPVLADPGRLEQVLINLMDNALKYTPPGGTITLSADEADGMVRVSVHDTGIGIPPKDLP
CCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHH
RIFERFYRVDAARSRDEGGTGLGLSIVKHIIQLHGGSITVESEHGKGTTFRFTLRKT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]