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The map label for this gene is dnaA [H]

Identifier: 39996180

GI number: 39996180

Start: 1166019

End: 1166795

Strand: Direct

Name: dnaA [H]

Synonym: GSU1078

Alternate gene names: 39996180

Gene position: 1166019-1166795 (Clockwise)

Preceding gene: 39996179

Following gene: 39996181

Centisome position: 30.57

GC content: 61.52

Gene sequence:

>777_bases
TTGCGCCCGCGCCCGGGCAAGGCGCGCTCTTCTAGGCCGTTTCCCGCCATGCAACTCGTCTTCGACTTTCCCGTCACCCC
CAAATACTCGTTCGACAATTTCGTGATCTGTGCCGGCAACGAGACTGCCTGCCGTTTCGCCCGGCGCCTGACGGACGAAA
GCGGTTCGGAAAATCTCCTCTACCTCCATGGGCCCTCCGGTTCGGGCAAGACTCATCTGCTCATGGCAATGGGGGCCTGT
TTTGCGGGCCGGGTCGGGCTTAGGGCAGTGCCATGCATCTCTTTCAAGGATGTTGACGAGATCTACCACGGCGAGTATCC
GGCCGAAGAGGTCTCAAGGTTGGCCGAGCGTTTTCGCGGCGCGCCAGCCCTTCTTGTGGATGATCTCCACCTGATCCCCG
ATCAGCAGAGTGTCCGGGTGGAGCTCTGGCAGCTGTTCAACGACTTCTACCAGGCCGGCCGGCCCATAGCCATCACCGGG
CTCAACCCCCCCAACGAACTTCCCACCCTCGATGGTCACCTGACTTCGCGTCTGCTCTGGGGGCTCGTGGCGAAAACCGA
TATTTCGGACGACGATTCCCGTCGCCGCATCATGCAGAAGCTGGCAGATGACCGTCAAATCATCCTTCCCGCCGACGCGG
TCGACTACCTTCTGGTGCATGTACGCCGCGACGTGCCGTCCCTTGTTGCCGCGCTGGACGCGATAACCCGCTATGCCTTC
AGCGCCAAACGGAAGATTACCATGCGACTGGCGCGCGAGGCACTGGCGCTTCTCTAG

Upstream 100 bases:

>100_bases
GAGGATGTCTACGAGCCGTTCCTGATCCAGCACGGTTTCATTAACCGCACCCCCCGGGGCCGCGTGGCCACGAAGTCCGC
CTATGAGCACTTCGGCCGCA

Downstream 100 bases:

>100_bases
GATTTGTCTGCCGCCGCCCGCGCGGGTTGTCTCCTGTAAGGTTTTACTTGCTTGCCGCGACAGGGAAATGTAAGTTTTTG
CGACAAAATCGCATAGTGAT

Product: chromosomal replication initiator protein DnaA, truncation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRPRPGKARSSRPFPAMQLVFDFPVTPKYSFDNFVICAGNETACRFARRLTDESGSENLLYLHGPSGSGKTHLLMAMGAC
FAGRVGLRAVPCISFKDVDEIYHGEYPAEEVSRLAERFRGAPALLVDDLHLIPDQQSVRVELWQLFNDFYQAGRPIAITG
LNPPNELPTLDGHLTSRLLWGLVAKTDISDDDSRRRIMQKLADDRQIILPADAVDYLLVHVRRDVPSLVAALDAITRYAF
SAKRKITMRLAREALALL

Sequences:

>Translated_258_residues
MRPRPGKARSSRPFPAMQLVFDFPVTPKYSFDNFVICAGNETACRFARRLTDESGSENLLYLHGPSGSGKTHLLMAMGAC
FAGRVGLRAVPCISFKDVDEIYHGEYPAEEVSRLAERFRGAPALLVDDLHLIPDQQSVRVELWQLFNDFYQAGRPIAITG
LNPPNELPTLDGHLTSRLLWGLVAKTDISDDDSRRRIMQKLADDRQIILPADAVDYLLVHVRRDVPSLVAALDAITRYAF
SAKRKITMRLAREALALL
>Mature_258_residues
MRPRPGKARSSRPFPAMQLVFDFPVTPKYSFDNFVICAGNETACRFARRLTDESGSENLLYLHGPSGSGKTHLLMAMGAC
FAGRVGLRAVPCISFKDVDEIYHGEYPAEEVSRLAERFRGAPALLVDDLHLIPDQQSVRVELWQLFNDFYQAGRPIAITG
LNPPNELPTLDGHLTSRLLWGLVAKTDISDDDSRRRIMQKLADDRQIILPADAVDYLLVHVRRDVPSLVAALDAITRYAF
SAKRKITMRLAREALALL

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=235, Percent_Identity=31.063829787234, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI226510964, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 28864; Mature: 28864

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRPGKARSSRPFPAMQLVFDFPVTPKYSFDNFVICAGNETACRFARRLTDESGSENLL
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEE
YLHGPSGSGKTHLLMAMGACFAGRVGLRAVPCISFKDVDEIYHGEYPAEEVSRLAERFRG
EEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
APALLVDDLHLIPDQQSVRVELWQLFNDFYQAGRPIAITGLNPPNELPTLDGHLTSRLLW
CCEEEECCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHH
GLVAKTDISDDDSRRRIMQKLADDRQIILPADAVDYLLVHVRRDVPSLVAALDAITRYAF
HHHHHCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKRKITMRLAREALALL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPRPGKARSSRPFPAMQLVFDFPVTPKYSFDNFVICAGNETACRFARRLTDESGSENLL
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEE
YLHGPSGSGKTHLLMAMGACFAGRVGLRAVPCISFKDVDEIYHGEYPAEEVSRLAERFRG
EEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
APALLVDDLHLIPDQQSVRVELWQLFNDFYQAGRPIAITGLNPPNELPTLDGHLTSRLLW
CCEEEECCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHH
GLVAKTDISDDDSRRRIMQKLADDRQIILPADAVDYLLVHVRRDVPSLVAALDAITRYAF
HHHHHCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKRKITMRLAREALALL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]