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The map label for this gene is sucD [H]

Identifier: 39996161

GI number: 39996161

Start: 1145107

End: 1145982

Strand: Direct

Name: sucD [H]

Synonym: GSU1059

Alternate gene names: 39996161

Gene position: 1145107-1145982 (Clockwise)

Preceding gene: 39996160

Following gene: 39996164

Centisome position: 30.02

GC content: 63.13

Gene sequence:

>876_bases
ATGTCCATACTCATCAACAGCGATTCGAAAATAGTCGTTCAGGGCATAACCGGCCGCAGCGGTCTCTTCCATACCCAGCA
GTGCCGGGACTACGGCACCAGGATCGTGGCCGGCGTCACCCCCGGCAAGGGGGGGATTCACATCGAAGGGATACCGGTCT
TCAACAGCGTCGAGGAAGCGGTCAGGTACACCGGGGCCAATGTGTCCATGATCTTCGTCCCGCCGCCGGCCGCGGCCGAC
GCCATCCTTGAGGCGGCCGACGCGGGACTGGAACTGGCGGTCTGCATCACCGAAGGAATCCCGGTGCGCGACATGGTTCC
GGTGAAGCGCATCCTCCAGGAGAGCCGGACCCGGCTCGTGGGACCGAACTGCCCTGGCGTCATCACTCCGGGCGAGTGCA
AGGTGGGGATTATGCCCGGCTACATTCATAAGCCCGGCAAGATTGGTGTGGTCTCCCGCAGCGGCACCCTCACCTACGAG
GCGGTCAAGCAGATCACCGAGGCGGGGCTCGGTCAGTCCACCTGCGTCGGCATCGGCGGCGACCCGATCATCGGCATGAA
CTTCATTGACGTGCTCAAGCTCTTTAACGAGGACAAGAACACCGAGGCGGTCTTCATGATCGGTGAGATCGGCGGCACTG
CCGAGGAAGAAGCGGCCTACTGGATCAAGGAAAACATGAAGAAGCCGGTGGCATCCTTTATCGCCGGCGTCACCGCGCCT
CCGGGCAAGAGGATGGGGCATGCCGGCGCCATCATCACCGGCGGCAAGGGAAAAGCCGAGGACAAGATCCGGACCCTTTC
CGAATGCGGGGTGGTGGTGGCCACCAGCCCCACCAAGATGGGCGTCGCCATGCTGGAAGCCCTGGGCAAGGGCTAG

Upstream 100 bases:

>100_bases
ATGCTCGGGTGAACGGGTCCGTAGGGGCGATCCTTGTGATCGCCTTCTGTCAGGGCAAACACAAGGTTTGCCCCTACACA
TCAATTGACGGAGATCATCA

Downstream 100 bases:

>100_bases
GCGGTTCCGTTACCCTGTGGCTGAGCCCGTACCCTCGCGGGGGTACGGGTTTTTTCGTTCATTTCAGGAGGCCAGGGGCA
TGACCTCGGCCGACGGCACG

Product: succinyl-CoA synthase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSILINSDSKIVVQGITGRSGLFHTQQCRDYGTRIVAGVTPGKGGIHIEGIPVFNSVEEAVRYTGANVSMIFVPPPAAAD
AILEAADAGLELAVCITEGIPVRDMVPVKRILQESRTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYE
AVKQITEAGLGQSTCVGIGGDPIIGMNFIDVLKLFNEDKNTEAVFMIGEIGGTAEEEAAYWIKENMKKPVASFIAGVTAP
PGKRMGHAGAIITGGKGKAEDKIRTLSECGVVVATSPTKMGVAMLEALGKG

Sequences:

>Translated_291_residues
MSILINSDSKIVVQGITGRSGLFHTQQCRDYGTRIVAGVTPGKGGIHIEGIPVFNSVEEAVRYTGANVSMIFVPPPAAAD
AILEAADAGLELAVCITEGIPVRDMVPVKRILQESRTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYE
AVKQITEAGLGQSTCVGIGGDPIIGMNFIDVLKLFNEDKNTEAVFMIGEIGGTAEEEAAYWIKENMKKPVASFIAGVTAP
PGKRMGHAGAIITGGKGKAEDKIRTLSECGVVVATSPTKMGVAMLEALGKG
>Mature_290_residues
SILINSDSKIVVQGITGRSGLFHTQQCRDYGTRIVAGVTPGKGGIHIEGIPVFNSVEEAVRYTGANVSMIFVPPPAAADA
ILEAADAGLELAVCITEGIPVRDMVPVKRILQESRTRLVGPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEA
VKQITEAGLGQSTCVGIGGDPIIGMNFIDVLKLFNEDKNTEAVFMIGEIGGTAEEEAAYWIKENMKKPVASFIAGVTAPP
GKRMGHAGAIITGGKGKAEDKIRTLSECGVVVATSPTKMGVAMLEALGKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=293, Percent_Identity=59.3856655290102, Blast_Score=300, Evalue=8e-82,
Organism=Homo sapiens, GI38569423, Length=248, Percent_Identity=30.6451612903226, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI38569421, Length=248, Percent_Identity=30.6451612903226, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=62.5, Blast_Score=364, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550194, Length=295, Percent_Identity=60, Blast_Score=334, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=58.9041095890411, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17557344, Length=303, Percent_Identity=25.4125412541254, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=303, Percent_Identity=24.7524752475248, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=298, Percent_Identity=51.3422818791946, Blast_Score=286, Evalue=3e-78,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=53.4246575342466, Blast_Score=313, Evalue=6e-86,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=57.1428571428571, Blast_Score=311, Evalue=3e-85,
Organism=Drosophila melanogaster, GI281363475, Length=314, Percent_Identity=26.1146496815287, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363473, Length=314, Percent_Identity=26.1146496815287, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363477, Length=314, Percent_Identity=26.1146496815287, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30331; Mature: 30200

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINSDSKIVVQGITGRSGLFHTQQCRDYGTRIVAGVTPGKGGIHIEGIPVFNSVEEA
CEEEEECCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCCEEEEEECCHHHHHHH
VRYTGANVSMIFVPPPAAADAILEAADAGLELAVCITEGIPVRDMVPVKRILQESRTRLV
HHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCEEE
GPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEAVKQITEAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPIIGMNFIDVLKLFNEDKNTEAVFMIGEIGGTAEEEAAYWIKENMKKPVASFIAGVTAP
CCEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAEDKIRTLSECGVVVATSPTKMGVAMLEALGKG
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILINSDSKIVVQGITGRSGLFHTQQCRDYGTRIVAGVTPGKGGIHIEGIPVFNSVEEA
EEEEECCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCCEEEEEECCHHHHHHH
VRYTGANVSMIFVPPPAAADAILEAADAGLELAVCITEGIPVRDMVPVKRILQESRTRLV
HHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCEEE
GPNCPGVITPGECKVGIMPGYIHKPGKIGVVSRSGTLTYEAVKQITEAGLGQSTCVGIGG
CCCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPIIGMNFIDVLKLFNEDKNTEAVFMIGEIGGTAEEEAAYWIKENMKKPVASFIAGVTAP
CCEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGKRMGHAGAIITGGKGKAEDKIRTLSECGVVVATSPTKMGVAMLEALGKG
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA