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The map label for this gene is sucC

Identifier: 39996160

GI number: 39996160

Start: 1143861

End: 1145018

Strand: Direct

Name: sucC

Synonym: GSU1058

Alternate gene names: 39996160

Gene position: 1143861-1145018 (Clockwise)

Preceding gene: 39996153

Following gene: 39996161

Centisome position: 29.99

GC content: 63.3

Gene sequence:

>1158_bases
ATGAACATTCATGAGTACCAGGCAAAGGAAATACTGAGCGCCTACGGCATCCCGGTGCCCCGGGGGCGGGTGGCCCTCAC
CTCCGACCAGGTGGAGCGGGCGGCCAAGGAGATGGGGGGGCGTTGCGTCATCAAGGCCCAGATCTATGCCGGCGGACGCG
GCAAGGCCGGCGGCGTCAAACTGGTCCATCATCCGGAGCAGGCCCAGGATTACGGCAAGGAGCTTTTCGGGCGTCGCCTC
ATCACCCCCCAGACCGGTCCCGAAGGTCTCAAGGTCCGCCGCATCCTGGTGGAGGAGGCCGTGGAGATCGCCCGCGAGTT
TTATCTCTCCATTACTCTCGACCGTTCCACCTCTCGCTACTGCCTCATCGCTTCGGCCGAAGGGGGAGTGGACATCGAGG
AGGTGGTCCAGAAGTCCCCCGACAAGATCCATGTTCTCACCATCGACCCTTACACGGGCCTTCGTCCGTTCCAGGCCCGC
CGCATCGCCCTGGCCCTCGGGCTTTCCGGCACCCTCTGCGAGGACTGCGTGGAGCTGATGCTCAATCTCTACAAGGTGGT
TCTGGAAAAGGACTGCTCGCTGGTCGAAATCAACCCCCTGGTGGTCACCCGGGCTGGTTGGCTCATGGCCATGGACGCCA
AGATCAACTTTGACGACAACGCCATCTTCCGGCACCGGGAATACCCGGACATGATGGATTACTCCCAGCTCGACACCCTG
GAGATCAATGCCGGCAAGTACGATCTCTCCTACATCAAGCTCTCCGGCAATATCGGCTGCATGGTCAACGGCGCGGGGCT
CGCCATGGCCACTCTCGACGTGCTCAAGGAGTTCGGTGGCGAGCCGGCCAACTTCCTGGACGTCGGCGGCGGCGCCACGC
GCGAGAAGGTGGCCGAGGCCTTCAAGATCATCCTGGAGGATGCGGACGTGAAGGGGGTCTTCGTTAATATCTTCGGCGGG
ATCATGCGCTGCGACGTGATCGCCCAGGGGATCATCGAGGCCGCCAGCGAGGTGCACTGCACCCTGCCGATCGTGGTCCG
GATGGACGGCAGCAAGGTGGCGGAAGGGAAGCAGCTCTTGGTCGAATCGGGGCTCAACGTCCAGACCGCCGACTCCCTGG
GCGAGGGGGCGGAACGGATCGTGGGGATGCTCGGGTGA

Upstream 100 bases:

>100_bases
AGGAGTAAACAGTTAAGGTTGATCGTGTGAATTTGTCTTACCATTCGCATTGCGTTTATGGTATACATAAAACTGTTTTA
TTAATACTAAAGGGGGCGTC

Downstream 100 bases:

>100_bases
ACGGGTCCGTAGGGGCGATCCTTGTGATCGCCTTCTGTCAGGGCAAACACAAGGTTTGCCCCTACACATCAATTGACGGA
GATCATCAATGTCCATACTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGRRL
ITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRYCLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQAR
RIALALGLSGTLCEDCVELMLNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLLVESGLNVQTADSLGEGAERIVGMLG

Sequences:

>Translated_385_residues
MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGRRL
ITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRYCLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQAR
RIALALGLSGTLCEDCVELMLNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLLVESGLNVQTADSLGEGAERIVGMLG
>Mature_385_residues
MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGRRL
ITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRYCLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQAR
RIALALGLSGTLCEDCVELMLNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTL
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGG
IMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLLVESGLNVQTADSLGEGAERIVGMLG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=45.0127877237852, Blast_Score=344, Evalue=8e-95,
Organism=Homo sapiens, GI157779135, Length=381, Percent_Identity=44.3569553805774, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI294862256, Length=391, Percent_Identity=42.4552429667519, Blast_Score=303, Evalue=1e-82,
Organism=Escherichia coli, GI1786948, Length=382, Percent_Identity=50, Blast_Score=380, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=46.4102564102564, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=40.8629441624365, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=44.3877551020408, Blast_Score=343, Evalue=3e-95,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=45.5242966751918, Blast_Score=334, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=45.5242966751918, Blast_Score=334, Evalue=6e-92,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=45.6632653061224, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=45.6632653061224, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=40.4040404040404, Blast_Score=300, Evalue=9e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_GEOSL (Q74EA5)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952111.1
- HSSP:   P0A836
- ProteinModelPortal:   Q74EA5
- SMR:   Q74EA5
- GeneID:   2686962
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1058
- NMPDR:   fig|243231.1.peg.1049
- TIGR:   GSU1058
- HOGENOM:   HBG315432
- OMA:   LPIVVRM
- ProtClustDB:   PRK00696
- BioCyc:   GSUL243231:GSU_1058-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41880; Mature: 41880

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDYGKELFGRRLITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRY
EEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCE
CLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQARRIALALGLSGTLCEDCVELM
EEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCHHHEEEEEECCCCHHHHHHHHHH
LNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTL
HHHHHHHHHCCCCEEEECCEEEEECCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCEE
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEA
EECCCEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILEDADVKGVFVNIFGGIMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLL
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHH
VESGLNVQTADSLGEGAERIVGMLG
HHCCCCEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVK
CCCHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
LVHHPEQAQDYGKELFGRRLITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRY
EEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCE
CLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQARRIALALGLSGTLCEDCVELM
EEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCHHHEEEEEECCCCHHHHHHHHHH
LNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTL
HHHHHHHHHCCCCEEEECCEEEEECCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCEE
EINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEA
EECCCEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
FKIILEDADVKGVFVNIFGGIMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLL
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHH
VESGLNVQTADSLGEGAERIVGMLG
HHCCCCEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA