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The map label for this gene is atoS [H]

Identifier: 39996065

GI number: 39996065

Start: 1036181

End: 1038148

Strand: Direct

Name: atoS [H]

Synonym: GSU0962

Alternate gene names: 39996065

Gene position: 1036181-1038148 (Clockwise)

Preceding gene: 39996063

Following gene: 39996066

Centisome position: 27.17

GC content: 61.99

Gene sequence:

>1968_bases
ATGCGCCGGTATCTTTTCAGCTTCATGACCAATCTAAAGCTCCGCTGGAAGATGCTGGTACTGGTGATGCCGCTGGTGAT
CATTCCCATTTTCGTGGTGGGCGGGGTGATCGGCTACATCTCCACCAAGCAGGCCTACCGGGGGATCACCCAGACCTCCC
GGGACGACCTGGAGCACATGGCCAGCTTCACCATCGATCTCCTCAATTCCCACTACCAGCAGTTCCAGGTCTACAAGCAG
GACAAGATGCGGACCGTGCACCTGGAACTGGCCACCCTCACCAATCTTTCCTACAACCTGGTCGAGGCCCAGGACCGCCA
GTACCGGGCCGGCAAGGTGGACCTGCGCACCGCCAAGGAGGAGGCCCGCAAGGCCCTCAAGCGGGTCAGCGTCGGCATGA
CCGGCTATATCTACGCCATGACCACCAAGGGGCTGCTGGAAGTCCACGTGGCGCGGGAAGGGGAGAACGTCTACGACGAG
AAGGACGAGAACGGTCGCCCCTTTATCCGGATCATGTGCGAGAACGCGCTCAAGGCCAAGCCGGGGGAGGTGCTCTATAT
CGTCTACCCCTGGCGCAACGAGGTGCTGGGAGACAAGTATCCCCGCAAAAAGGTGGTGGCTTACCGGTACTTCCCCCAGT
GGGACTGGATCATCGCGTCGGGCGGCTATCTGGAGGAGACCTATGAGGACGTGGCCTTCGAGCGCCGCTCCTTTGCCGAG
CTGAAGGAGAAGATCCGCAGCAAGAAGGTGGGGGAGACCGGCTACATCTTCTGCATGGACGATACGGGGACCTTTACCAT
CCACCCCTCGGGCGAGGGGCAGAATTTCCTCAATGCGGTCGACTCCAGCGGCAACAAGTTCATCAAGGAGATGGTGGAGA
AGAAGCGCGGGTGGATTCGCTACCCCTGGCGCAACAAGGGAGACGCGTCGCCGCGGATGAAGCTCGTGCGCTACGACTAC
TTCAAGCCTTGGGGATGGATCGTGGCGGTCGGGTCCTATGAGGACGAGTTCTACCGGGAGGCCAACAAGATCCGGGGGCG
CATCGTCACCACCATGACGCTGCTGACCATCCTCACCGGCCTCGTGGCAACGGGGCTGGTTTTTCTCGCCGCCAAGGTGT
TCACCGACCCCATCAACTACATGATCGACGTGATCAGGAAGGTAAAGAAGGGGCGTCTGGACGAGCAGATGGAGGTTGAC
ACCGGCGATGAGCTGGGCGAGCTTGCCGGCGCCTTCAACCGGATGACCACCATCATCCGCCAGAACAAGGAGATGGAGGC
GAGCCTGGCTCAGCAGGGGAAGATGGCATCGCTCGGCGTCCTCTCTTCGGGCGTTGCCCATGAGATCAACAACCCCCTGG
GGGTGATCCTCGGCTATGCCTCGTACCTGGAGTCGAAGATCACCGAAGAGGACCCGACCTACAAATATATCCACGAGATC
AAGCGCGAGAGCAAGCGGTGCAAGAAGATCGTCCAGGATCTCCTCTCCTACGCCCGGACCCCCAAGCCCGCCCTGGAGCC
CACCGACATCAACGACCTCCTGGGTCAGATCGTGGGGTTTGCCGCCAACCACACCGACATGCACCACGTGACCGTGGTCC
GGGAGTTCGCGCCCGACTTGCCGCCGGTCATGGCCGACGGCGACCAGATCCGCCAGGTGGCCATCAACCTGATCCTCAAT
GCCGGCTCCGCCATGACCGCCGGCGGCGTCCTTACCGTCCGGACGTTCCTGGACCAGGAGCAGTACGTGAACATCGTGTT
CAGCGACACCGGCTGCGGCATCCCCCGCGAGGATCAGGAGCGGATATTCGAGCCGTTCTTCACCACCAAGACCAAGGGGA
CCGGCCTGGGGCTCGCCATTACGCGCCAGATCGTGGAGATGCACCACGGCCGCATCGCCATCGACAGCGAGGTGGGGCGC
GGCACCGACGTTACCGTGCGCCTGCCCCTGGAGCCGGAAGAGCTGTAG

Upstream 100 bases:

>100_bases
GTCAAAACTAGATGTTTTCGCAAAAATGCAAAAATAACTGGATTTTTTTTTGGTGTTTACATACTATCCTCCGTGACTCC
GCACAGATGGAAGAGGCCCC

Downstream 100 bases:

>100_bases
CGTTAATATCAGTTGAGAGGTGCCGATCGTGTCAGATAAAAAGCGCATCATGCTTATCGATAACGAAGAAGGGCTCTGCC
GCATGATGGAGGCGGTGCTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MRRYLFSFMTNLKLRWKMLVLVMPLVIIPIFVVGGVIGYISTKQAYRGITQTSRDDLEHMASFTIDLLNSHYQQFQVYKQ
DKMRTVHLELATLTNLSYNLVEAQDRQYRAGKVDLRTAKEEARKALKRVSVGMTGYIYAMTTKGLLEVHVAREGENVYDE
KDENGRPFIRIMCENALKAKPGEVLYIVYPWRNEVLGDKYPRKKVVAYRYFPQWDWIIASGGYLEETYEDVAFERRSFAE
LKEKIRSKKVGETGYIFCMDDTGTFTIHPSGEGQNFLNAVDSSGNKFIKEMVEKKRGWIRYPWRNKGDASPRMKLVRYDY
FKPWGWIVAVGSYEDEFYREANKIRGRIVTTMTLLTILTGLVATGLVFLAAKVFTDPINYMIDVIRKVKKGRLDEQMEVD
TGDELGELAGAFNRMTTIIRQNKEMEASLAQQGKMASLGVLSSGVAHEINNPLGVILGYASYLESKITEEDPTYKYIHEI
KRESKRCKKIVQDLLSYARTPKPALEPTDINDLLGQIVGFAANHTDMHHVTVVREFAPDLPPVMADGDQIRQVAINLILN
AGSAMTAGGVLTVRTFLDQEQYVNIVFSDTGCGIPREDQERIFEPFFTTKTKGTGLGLAITRQIVEMHHGRIAIDSEVGR
GTDVTVRLPLEPEEL

Sequences:

>Translated_655_residues
MRRYLFSFMTNLKLRWKMLVLVMPLVIIPIFVVGGVIGYISTKQAYRGITQTSRDDLEHMASFTIDLLNSHYQQFQVYKQ
DKMRTVHLELATLTNLSYNLVEAQDRQYRAGKVDLRTAKEEARKALKRVSVGMTGYIYAMTTKGLLEVHVAREGENVYDE
KDENGRPFIRIMCENALKAKPGEVLYIVYPWRNEVLGDKYPRKKVVAYRYFPQWDWIIASGGYLEETYEDVAFERRSFAE
LKEKIRSKKVGETGYIFCMDDTGTFTIHPSGEGQNFLNAVDSSGNKFIKEMVEKKRGWIRYPWRNKGDASPRMKLVRYDY
FKPWGWIVAVGSYEDEFYREANKIRGRIVTTMTLLTILTGLVATGLVFLAAKVFTDPINYMIDVIRKVKKGRLDEQMEVD
TGDELGELAGAFNRMTTIIRQNKEMEASLAQQGKMASLGVLSSGVAHEINNPLGVILGYASYLESKITEEDPTYKYIHEI
KRESKRCKKIVQDLLSYARTPKPALEPTDINDLLGQIVGFAANHTDMHHVTVVREFAPDLPPVMADGDQIRQVAINLILN
AGSAMTAGGVLTVRTFLDQEQYVNIVFSDTGCGIPREDQERIFEPFFTTKTKGTGLGLAITRQIVEMHHGRIAIDSEVGR
GTDVTVRLPLEPEEL
>Mature_655_residues
MRRYLFSFMTNLKLRWKMLVLVMPLVIIPIFVVGGVIGYISTKQAYRGITQTSRDDLEHMASFTIDLLNSHYQQFQVYKQ
DKMRTVHLELATLTNLSYNLVEAQDRQYRAGKVDLRTAKEEARKALKRVSVGMTGYIYAMTTKGLLEVHVAREGENVYDE
KDENGRPFIRIMCENALKAKPGEVLYIVYPWRNEVLGDKYPRKKVVAYRYFPQWDWIIASGGYLEETYEDVAFERRSFAE
LKEKIRSKKVGETGYIFCMDDTGTFTIHPSGEGQNFLNAVDSSGNKFIKEMVEKKRGWIRYPWRNKGDASPRMKLVRYDY
FKPWGWIVAVGSYEDEFYREANKIRGRIVTTMTLLTILTGLVATGLVFLAAKVFTDPINYMIDVIRKVKKGRLDEQMEVD
TGDELGELAGAFNRMTTIIRQNKEMEASLAQQGKMASLGVLSSGVAHEINNPLGVILGYASYLESKITEEDPTYKYIHEI
KRESKRCKKIVQDLLSYARTPKPALEPTDINDLLGQIVGFAANHTDMHHVTVVREFAPDLPPVMADGDQIRQVAINLILN
AGSAMTAGGVLTVRTFLDQEQYVNIVFSDTGCGIPREDQERIFEPFFTTKTKGTGLGLAITRQIVEMHHGRIAIDSEVGR
GTDVTVRLPLEPEEL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=34.251968503937, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=35.5932203389831, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=27.972027972028, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790300, Length=223, Percent_Identity=32.7354260089686, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789149, Length=310, Percent_Identity=24.8387096774194, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=305, Percent_Identity=27.2131147540984, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=27.6315789473684, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=29.8319327731092, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786783, Length=319, Percent_Identity=24.4514106583072, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789808, Length=309, Percent_Identity=23.9482200647249, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=22.8915662650602, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=25.9433962264151, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74562; Mature: 74562

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYLFSFMTNLKLRWKMLVLVMPLVIIPIFVVGGVIGYISTKQAYRGITQTSRDDLEHM
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ASFTIDLLNSHYQQFQVYKQDKMRTVHLELATLTNLSYNLVEAQDRQYRAGKVDLRTAKE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCEEEEECCCCCCCCCCCHHHHHHH
EARKALKRVSVGMTGYIYAMTTKGLLEVHVAREGENVYDEKDENGRPFIRIMCENALKAK
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECHHCCCC
PGEVLYIVYPWRNEVLGDKYPRKKVVAYRYFPQWDWIIASGGYLEETYEDVAFERRSFAE
CCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
LKEKIRSKKVGETGYIFCMDDTGTFTIHPSGEGQNFLNAVDSSGNKFIKEMVEKKRGWIR
HHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCCEEE
YPWRNKGDASPRMKLVRYDYFKPWGWIVAVGSYEDEFYREANKIRGRIVTTMTLLTILTG
CCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVATGLVFLAAKVFTDPINYMIDVIRKVKKGRLDEQMEVDTGDELGELAGAFNRMTTIIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QNKEMEASLAQQGKMASLGVLSSGVAHEINNPLGVILGYASYLESKITEEDPTYKYIHEI
CCCHHHHHHHHCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KRESKRCKKIVQDLLSYARTPKPALEPTDINDLLGQIVGFAANHTDMHHVTVVREFAPDL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
PPVMADGDQIRQVAINLILNAGSAMTAGGVLTVRTFLDQEQYVNIVFSDTGCGIPREDQE
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHH
RIFEPFFTTKTKGTGLGLAITRQIVEMHHGRIAIDSEVGRGTDVTVRLPLEPEEL
HHHCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRRYLFSFMTNLKLRWKMLVLVMPLVIIPIFVVGGVIGYISTKQAYRGITQTSRDDLEHM
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ASFTIDLLNSHYQQFQVYKQDKMRTVHLELATLTNLSYNLVEAQDRQYRAGKVDLRTAKE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCEEEEECCCCCCCCCCCHHHHHHH
EARKALKRVSVGMTGYIYAMTTKGLLEVHVAREGENVYDEKDENGRPFIRIMCENALKAK
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECHHCCCC
PGEVLYIVYPWRNEVLGDKYPRKKVVAYRYFPQWDWIIASGGYLEETYEDVAFERRSFAE
CCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
LKEKIRSKKVGETGYIFCMDDTGTFTIHPSGEGQNFLNAVDSSGNKFIKEMVEKKRGWIR
HHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCCEEE
YPWRNKGDASPRMKLVRYDYFKPWGWIVAVGSYEDEFYREANKIRGRIVTTMTLLTILTG
CCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVATGLVFLAAKVFTDPINYMIDVIRKVKKGRLDEQMEVDTGDELGELAGAFNRMTTIIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QNKEMEASLAQQGKMASLGVLSSGVAHEINNPLGVILGYASYLESKITEEDPTYKYIHEI
CCCHHHHHHHHCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KRESKRCKKIVQDLLSYARTPKPALEPTDINDLLGQIVGFAANHTDMHHVTVVREFAPDL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
PPVMADGDQIRQVAINLILNAGSAMTAGGVLTVRTFLDQEQYVNIVFSDTGCGIPREDQE
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHH
RIFEPFFTTKTKGTGLGLAITRQIVEMHHGRIAIDSEVGRGTDVTVRLPLEPEEL
HHHCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]