| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
Click here to switch to the map view.
The map label for this gene is aprN [H]
Identifier: 39995997
GI number: 39995997
Start: 951817
End: 954297
Strand: Direct
Name: aprN [H]
Synonym: GSU0891
Alternate gene names: 39995997
Gene position: 951817-954297 (Clockwise)
Preceding gene: 39995992
Following gene: 39995999
Centisome position: 24.95
GC content: 66.79
Gene sequence:
>2481_bases ATGGCAATTTGCGCTCCCGGCCGGGACGGGGCATTAGGGCCTCGCGGTTTCAGTCCGGTATCTGTTATAGTGGAGGCTCG GGGCGCAGAACAGGGACCGGCGGGCAGCATTTCCACCCCGCCGCGAGAAGGGGATACCGTGAAGCATGGAGTATGGGAGC GTGTGAGCGTGATGTGCCGGTTTCTGCCGGTCCTGCTGGCAATGGCGACGGCGCCGGCATGGGCCGCGCCGGCTGCGGGG TCGAAGGTGCCCGCCGAGGTGGGGGCTGCCCTGGCGCGGGGCGAGTCCCGGGAATTGATCGTCCTGCTGGATGACGGCCC GGTGGAGGCCGAACTGGCGGGCATCCGGGCGCAATCCGCGTCGCCGGCCGACGAGCGGGAGGCGGCTCGCCGACGGCTCG CGCTGAAGTCGGCGCGGTACGGCGAGATGAAGGGGCGCCTCGCCGCCGACCTGGCGGAAGAGCGAATGGAGGTGGTCAGA GAGTACAGCCACCTGCCGCTCTTCTTCGCGCGGGTGGGATCGGCCAGGGCCCTTGAGCGGCTGGCGGGCCGCGCCGAGGT GAAGAGGGTTTTCCCCAACGAGGCCCGGAAGCTCCAGCTCACCGAGAGTCTTCCCCTGATTGAACAGCCCCGGGCCGCGG CTGCCGGTTTCACGGGCGCCGACACATCGGTGGCGGTCTTCGACACGGGGGTCGACTACACCCGGCCGGCCTTCGGCTCC TGCACCGCGCCGGGCACGCCGGCCGGGTGCAAGGTAATCGTGTCCATCGATACGGCGTCCCCGGATTTCCAGCTTGACGA CCCCGACTCCTATCACGGCACCGGCGTGTCCGCCATTGTCCTGGGGGTGGCTCCCGACACCCGCATCATCGCCATCGACG TCTTCGACGGTGAATACGCCTATGATGCGGACATCATCGAGGCCGCCAACTGGGCGATCGCCAATCGCGCCACCTACAAC ATCGTGGCCATCAACATGAGCCTTGGCGCGGGCTCGTTCACCTCGCCCTGCACCGATACCACCTACAATACCCTGGTGAG CCAGGTCCGCGCGGCAGGGATCATGCCCGTTGCCGCCTCGGGCAACGAAGGACTGACGAACGCCCTCATTGCGCCGGCAT GCATCCCGGGCGTGATTTCGGTGGGCGCGGTTTACGATGATTACAGCTACTTCCACGGAACCTGTCTCGATCCCATGGTG CCCGACAAGGTGGCCTGCTTCTCAAACAGCGCATCCTTTCTCACCCTGCTGGCCCCGGGGGCCTATATCACCGCGGCCGG AGAGCTCACGGCCGGCACCTCCGAGGCGACCCCCCATGTGTCGGGGGCCGTGGCGGTACTCCGATCGGCTTTTCCGGCGG AGTCCCTCGATGCGATTCAGGCGCGCCTCACCTCCACCGGCAAGCCGGTGACCGATTCCCGGAACGGGGTGACGAAACCG CGCATCAATGTTGCCGCGGCCATCGGCCCGCCCGCCAACGATCTCTTTTCCGCAGCCCAGGCCCTGCCCGCCACTGCCGG CCAGACTACCGGCGTCAACCTGAACGCCACCCGTGAGACAGGCGAGCCCGATCACGCGGGGGTGGCCGGGGGTGCCTCGG TCTGGTGGACCTGGCAGGGCCAGACCAGCGGAATCGTGTCCCTGGATACCCACGGCAGCTCCTTCGATACCCTGCTGGCG GTTTATACCGGCACCAGTGTGGGAAATCTGACGCCGGCCGCCGCCAATGACAACGACGGCGGCGTCGGCGGCACCAGCGG GCTGACCTTTACGGCCTTGGCGGGAGAGGTGTACCGGATTGCCGTGGACGGCCGGAACGGAGTCACGGGGCGCATTACCC TGAACCGGAACTTTACCCCGTCGGCCACAGCAGATATTGCCGTCGCCGCCTCGGGAGCACCGTCGACGAGCTTCGTGGGG GAACTGGTAACCTACACGGTGAGTGTCATCAACTACGGCCCGGAGACGGCAACCGAGGTGACGGTGACCGATCCGATCCC TGCGGGGGCCACCTTTGTTTCCGCTTCCCCGGGGTGCGCCCTGTCAGGCAGCACCGTTACGTGCAACATCGGAACCCTGG CAGTCGGGGGGAGCGTCTCCTACACCATCGTGCTTAGCCCCACGCTGGCTGGCACCCTGAGCAACACCTTCCAGGCGGCC GGTTTCACCAACGATCCCGCCCCGGGCAACAACGCCTCGGCTGTCTATACGCCGGTGGCTGCATTTGTGTATCCGGTGCT GGTGGACAATGTGCAGTATCCAATGCTTCAGAACGGCTTCGACATTGTCCAGGAGGGGGGCGTGGTCATGGCCACGGCGA GCCTGTTCACGGAACAGCTGCTGCTGAGCCGCGCCGTCCGGTTCACCCTGCAGGGAGGCTATGACGCCTTCTTCACCTCC GCCACCGGCTACACCACCCTGCAGGGGAGCCTGACCCTTGCCAGAGGGGCGGTGACCGTTGACCGGTTGATCGTCCGCTG A
Upstream 100 bases:
>100_bases GTTCAGTGCGGAGTGCGGCAACGCGGTCCGCGGCGGTCTGCTTGTCCATGGGGGCTCCGTGGCGTGGGGATAGAGGAGCT TATAGCACAGCGGCACCCGG
Downstream 100 bases:
>100_bases TCTGTTGCCGCAGCGTGCAGGGCTCCCGCGCCCTCCTCCGGGAGGCGAACCGGTACAGCAATTTGCCCTGGCACGAATAT CGCCGTCTTGATTTCCTCCC
Product: subtilase domain protein
Products: NA
Alternate protein names: Nattokinase [H]
Number of amino acids: Translated: 826; Mature: 825
Protein sequence:
>826_residues MAICAPGRDGALGPRGFSPVSVIVEARGAEQGPAGSISTPPREGDTVKHGVWERVSVMCRFLPVLLAMATAPAWAAPAAG SKVPAEVGAALARGESRELIVLLDDGPVEAELAGIRAQSASPADEREAARRRLALKSARYGEMKGRLAADLAEERMEVVR EYSHLPLFFARVGSARALERLAGRAEVKRVFPNEARKLQLTESLPLIEQPRAAAAGFTGADTSVAVFDTGVDYTRPAFGS CTAPGTPAGCKVIVSIDTASPDFQLDDPDSYHGTGVSAIVLGVAPDTRIIAIDVFDGEYAYDADIIEAANWAIANRATYN IVAINMSLGAGSFTSPCTDTTYNTLVSQVRAAGIMPVAASGNEGLTNALIAPACIPGVISVGAVYDDYSYFHGTCLDPMV PDKVACFSNSASFLTLLAPGAYITAAGELTAGTSEATPHVSGAVAVLRSAFPAESLDAIQARLTSTGKPVTDSRNGVTKP RINVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQGQTSGIVSLDTHGSSFDTLLA VYTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRIAVDGRNGVTGRITLNRNFTPSATADIAVAASGAPSTSFVG ELVTYTVSVINYGPETATEVTVTDPIPAGATFVSASPGCALSGSTVTCNIGTLAVGGSVSYTIVLSPTLAGTLSNTFQAA GFTNDPAPGNNASAVYTPVAAFVYPVLVDNVQYPMLQNGFDIVQEGGVVMATASLFTEQLLLSRAVRFTLQGGYDAFFTS ATGYTTLQGSLTLARGAVTVDRLIVR
Sequences:
>Translated_826_residues MAICAPGRDGALGPRGFSPVSVIVEARGAEQGPAGSISTPPREGDTVKHGVWERVSVMCRFLPVLLAMATAPAWAAPAAG SKVPAEVGAALARGESRELIVLLDDGPVEAELAGIRAQSASPADEREAARRRLALKSARYGEMKGRLAADLAEERMEVVR EYSHLPLFFARVGSARALERLAGRAEVKRVFPNEARKLQLTESLPLIEQPRAAAAGFTGADTSVAVFDTGVDYTRPAFGS CTAPGTPAGCKVIVSIDTASPDFQLDDPDSYHGTGVSAIVLGVAPDTRIIAIDVFDGEYAYDADIIEAANWAIANRATYN IVAINMSLGAGSFTSPCTDTTYNTLVSQVRAAGIMPVAASGNEGLTNALIAPACIPGVISVGAVYDDYSYFHGTCLDPMV PDKVACFSNSASFLTLLAPGAYITAAGELTAGTSEATPHVSGAVAVLRSAFPAESLDAIQARLTSTGKPVTDSRNGVTKP RINVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQGQTSGIVSLDTHGSSFDTLLA VYTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRIAVDGRNGVTGRITLNRNFTPSATADIAVAASGAPSTSFVG ELVTYTVSVINYGPETATEVTVTDPIPAGATFVSASPGCALSGSTVTCNIGTLAVGGSVSYTIVLSPTLAGTLSNTFQAA GFTNDPAPGNNASAVYTPVAAFVYPVLVDNVQYPMLQNGFDIVQEGGVVMATASLFTEQLLLSRAVRFTLQGGYDAFFTS ATGYTTLQGSLTLARGAVTVDRLIVR >Mature_825_residues AICAPGRDGALGPRGFSPVSVIVEARGAEQGPAGSISTPPREGDTVKHGVWERVSVMCRFLPVLLAMATAPAWAAPAAGS KVPAEVGAALARGESRELIVLLDDGPVEAELAGIRAQSASPADEREAARRRLALKSARYGEMKGRLAADLAEERMEVVRE YSHLPLFFARVGSARALERLAGRAEVKRVFPNEARKLQLTESLPLIEQPRAAAAGFTGADTSVAVFDTGVDYTRPAFGSC TAPGTPAGCKVIVSIDTASPDFQLDDPDSYHGTGVSAIVLGVAPDTRIIAIDVFDGEYAYDADIIEAANWAIANRATYNI VAINMSLGAGSFTSPCTDTTYNTLVSQVRAAGIMPVAASGNEGLTNALIAPACIPGVISVGAVYDDYSYFHGTCLDPMVP DKVACFSNSASFLTLLAPGAYITAAGELTAGTSEATPHVSGAVAVLRSAFPAESLDAIQARLTSTGKPVTDSRNGVTKPR INVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQGQTSGIVSLDTHGSSFDTLLAV YTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRIAVDGRNGVTGRITLNRNFTPSATADIAVAASGAPSTSFVGE LVTYTVSVINYGPETATEVTVTDPIPAGATFVSASPGCALSGSTVTCNIGTLAVGGSVSYTIVLSPTLAGTLSNTFQAAG FTNDPAPGNNASAVYTPVAAFVYPVLVDNVQYPMLQNGFDIVQEGGVVMATASLFTEQLLLSRAVRFTLQGGYDAFFTSA TGYTTLQGSLTLARGAVTVDRLIVR
Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Subtilisin NAT also has fibrinolytic activity [H]
COG id: COG1404
COG function: function code O; Subtilisin-like serine proteases
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S8 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000209 - InterPro: IPR022398 - InterPro: IPR015500 - InterPro: IPR009020 - InterPro: IPR010259 [H]
Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]
EC number: =3.4.21.62 [H]
Molecular weight: Translated: 84786; Mature: 84655
Theoretical pI: Translated: 4.57; Mature: 4.57
Prosite motif: PS00138 SUBTILASE_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAICAPGRDGALGPRGFSPVSVIVEARGAEQGPAGSISTPPREGDTVKHGVWERVSVMCR CEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH FLPVLLAMATAPAWAAPAAGSKVPAEVGAALARGESRELIVLLDDGPVEAELAGIRAQSA HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEECEECCCC SPADEREAARRRLALKSARYGEMKGRLAADLAEERMEVVREYSHLPLFFARVGSARALER CCCHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCHHHHHH LAGRAEVKRVFPNEARKLQLTESLPLIEQPRAAAAGFTGADTSVAVFDTGVDYTRPAFGS HHCHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCC CTAPGTPAGCKVIVSIDTASPDFQLDDPDSYHGTGVSAIVLGVAPDTRIIAIDVFDGEYA CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCEE YDADIIEAANWAIANRATYNIVAINMSLGAGSFTSPCTDTTYNTLVSQVRAAGIMPVAAS CCCHHHHHCCEEEECCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECC GNEGLTNALIAPACIPGVISVGAVYDDYSYFHGTCLDPMVPDKVACFSNSASFLTLLAPG CCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHEECCCCCCEEEEECCC AYITAAGELTAGTSEATPHVSGAVAVLRSAFPAESLDAIQARLTSTGKPVTDSRNGVTKP CEEEECCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC RINVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQG CEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECC QTSGIVSLDTHGSSFDTLLAVYTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRI CCCCEEEECCCCCCHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEE AVDGRNGVTGRITLNRNFTPSATADIAVAASGAPSTSFVGELVTYTVSVINYGPETATEV EECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEEEEEECCCCCCCEE TVTDPIPAGATFVSASPGCALSGSTVTCNIGTLAVGGSVSYTIVLSPTLAGTLSNTFQAA EEECCCCCCCEEEECCCCCEECCCEEEEECCEEEECCCEEEEEEECCCHHHHHHCCCEEC GFTNDPAPGNNASAVYTPVAAFVYPVLVDNVQYPMLQNGFDIVQEGGVVMATASLFTEQL CCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCEEEEEHHHHHHHH LLSRAVRFTLQGGYDAFFTSATGYTTLQGSLTLARGAVTVDRLIVR HHHHHHEEEECCCCCEEEECCCCCEEEECCEEEECCCEEHHHHHCC >Mature Secondary Structure AICAPGRDGALGPRGFSPVSVIVEARGAEQGPAGSISTPPREGDTVKHGVWERVSVMCR EEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH FLPVLLAMATAPAWAAPAAGSKVPAEVGAALARGESRELIVLLDDGPVEAELAGIRAQSA HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEECEECCCC SPADEREAARRRLALKSARYGEMKGRLAADLAEERMEVVREYSHLPLFFARVGSARALER CCCHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCHHHHHH LAGRAEVKRVFPNEARKLQLTESLPLIEQPRAAAAGFTGADTSVAVFDTGVDYTRPAFGS HHCHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCC CTAPGTPAGCKVIVSIDTASPDFQLDDPDSYHGTGVSAIVLGVAPDTRIIAIDVFDGEYA CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCEE YDADIIEAANWAIANRATYNIVAINMSLGAGSFTSPCTDTTYNTLVSQVRAAGIMPVAAS CCCHHHHHCCEEEECCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECC GNEGLTNALIAPACIPGVISVGAVYDDYSYFHGTCLDPMVPDKVACFSNSASFLTLLAPG CCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHEECCCCCCEEEEECCC AYITAAGELTAGTSEATPHVSGAVAVLRSAFPAESLDAIQARLTSTGKPVTDSRNGVTKP CEEEECCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC RINVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQG CEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECC QTSGIVSLDTHGSSFDTLLAVYTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRI CCCCEEEECCCCCCHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEE AVDGRNGVTGRITLNRNFTPSATADIAVAASGAPSTSFVGELVTYTVSVINYGPETATEV EECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEEEEEECCCCCCCEE TVTDPIPAGATFVSASPGCALSGSTVTCNIGTLAVGGSVSYTIVLSPTLAGTLSNTFQAA EEECCCCCCCEEEECCCCCEECCCEEEEECCEEEECCCEEEEEEECCCHHHHHHCCCEEC GFTNDPAPGNNASAVYTPVAAFVYPVLVDNVQYPMLQNGFDIVQEGGVVMATASLFTEQL CCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCEEEEEHHHHHHHH LLSRAVRFTLQGGYDAFFTSATGYTTLQGSLTLARGAVTVDRLIVR HHHHHHEEEECCCCCEEEECCCCCEEEECCEEEECCCEEHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1369081 [H]