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The map label for this gene is dagK [H]

Identifier: 39995982

GI number: 39995982

Start: 933685

End: 934554

Strand: Direct

Name: dagK [H]

Synonym: GSU0876

Alternate gene names: 39995982

Gene position: 933685-934554 (Clockwise)

Preceding gene: 39995981

Following gene: 39995983

Centisome position: 24.48

GC content: 69.66

Gene sequence:

>870_bases
ATGTCCGATCGCTGCACCCTTATCGTCAATCCCGTGTCCGGAAGCTACTCGGAGGCTGCCGTCAGCGCCGCCATGGACGC
CCTGCGCCGGGGAGGACTGGCCCCCCGCCTGCTTCTCACCGGCGGCCCCGACGATGCGGCCGCCTTTGCCGCTCGGCTCT
GCGCTCAGGAGGAGCATCCCTTCGTCATTGCCGTCGGGGGGGACGGAACCGTCAACGGCGTGCTGAACGGCCTCGAACCG
GGGCGCGCCACCCTCGGCTACATCCCCTTCGGTACCGCCAACGTGCTTGGGCGCGAGCTGGGGCTGCGTTCCGCCGAGGA
TGCCGTGGCCCGGATCGTGCGCCGGGAAACGCGTTCTCTCGCCACGGGGCTCCTGGAAGGGTTCGGAGTACGGCGGCGTT
TTTTTCTCATGGCCGGAATCGGCTTTGACGGCCAGGTGGTGGAGGGGGTGCGCAGCGACGAGAAGAAGCGCTTCGGCGCC
GGAGCATACCTTTTTTCAGCCATCAGGACCCTTGCCGCCTGGGACCGGCGGCTCCTGGAGGTGGAGGTGGACGGCGTCGC
CATCGCCTGCCACGGGGCGGTGATCTGCAACGCGGCCCGGTACGGGGGCCCCTTTACCTTGGCCCCGGGAGCGAACCTTT
TCCACGACGGATTTCGGGTCGTCCTGATCCGGGACCCGTCCCGATGGCGCTACCTCTCCCTTGCCCTGCGGGTGGCGGCG
GGGCGCCGCGCCGGCGGCGGCCCCGAGGTCGTATCGGCCCGGCGGGTAGCCGTGGGCGGCAACAAGCCCGTTCAGGTGGA
CGGCGACTTCATCTGCCACTCCCCGGTCACCGTGACTGCTGAGGCCGATTTCGCCCGGCTCGTGGTCTGA

Upstream 100 bases:

>100_bases
TTGTCATGATATGTCCGATTTAACGGAGCCGCGGAGAATCGGTTGACAGGGCGCCTCGTCCGCCCGGATAATGGCCCGGC
CGAACTGCCGGAGGAAGCCC

Downstream 100 bases:

>100_bases
CCCGGCCGGCTCACACGTCGGCGCACACGGCGAATGCCGCTACGGAGAAGAGGGCCGGCGACTCACCCTCCGAAAAAACT
CAAGCGTCGCCCCGCGTGGT

Product: diacylglycerol kinase catalytic subunit

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSDRCTLIVNPVSGSYSEAAVSAAMDALRRGGLAPRLLLTGGPDDAAAFAARLCAQEEHPFVIAVGGDGTVNGVLNGLEP
GRATLGYIPFGTANVLGRELGLRSAEDAVARIVRRETRSLATGLLEGFGVRRRFFLMAGIGFDGQVVEGVRSDEKKRFGA
GAYLFSAIRTLAAWDRRLLEVEVDGVAIACHGAVICNAARYGGPFTLAPGANLFHDGFRVVLIRDPSRWRYLSLALRVAA
GRRAGGGPEVVSARRVAVGGNKPVQVDGDFICHSPVTVTAEADFARLVV

Sequences:

>Translated_289_residues
MSDRCTLIVNPVSGSYSEAAVSAAMDALRRGGLAPRLLLTGGPDDAAAFAARLCAQEEHPFVIAVGGDGTVNGVLNGLEP
GRATLGYIPFGTANVLGRELGLRSAEDAVARIVRRETRSLATGLLEGFGVRRRFFLMAGIGFDGQVVEGVRSDEKKRFGA
GAYLFSAIRTLAAWDRRLLEVEVDGVAIACHGAVICNAARYGGPFTLAPGANLFHDGFRVVLIRDPSRWRYLSLALRVAA
GRRAGGGPEVVSARRVAVGGNKPVQVDGDFICHSPVTVTAEADFARLVV
>Mature_288_residues
SDRCTLIVNPVSGSYSEAAVSAAMDALRRGGLAPRLLLTGGPDDAAAFAARLCAQEEHPFVIAVGGDGTVNGVLNGLEPG
RATLGYIPFGTANVLGRELGLRSAEDAVARIVRRETRSLATGLLEGFGVRRRFFLMAGIGFDGQVVEGVRSDEKKRFGAG
AYLFSAIRTLAAWDRRLLEVEVDGVAIACHGAVICNAARYGGPFTLAPGANLFHDGFRVVLIRDPSRWRYLSLALRVAAG
RRAGGGPEVVSARRVAVGGNKPVQVDGDFICHSPVTVTAEADFARLVV

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 30476; Mature: 30345

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRCTLIVNPVSGSYSEAAVSAAMDALRRGGLAPRLLLTGGPDDAAAFAARLCAQEEHP
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCC
FVIAVGGDGTVNGVLNGLEPGRATLGYIPFGTANVLGRELGLRSAEDAVARIVRRETRSL
EEEEECCCCCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATGLLEGFGVRRRFFLMAGIGFDGQVVEGVRSDEKKRFGAGAYLFSAIRTLAAWDRRLLE
HHHHHHHCCHHEEEEEEECCCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHEEEE
VEVDGVAIACHGAVICNAARYGGPFTLAPGANLFHDGFRVVLIRDPSRWRYLSLALRVAA
EEECCEEEEECCEEEECHHHCCCCEEECCCCCEECCCEEEEEEECCCCHHHHHHHHHHHC
GRRAGGGPEVVSARRVAVGGNKPVQVDGDFICHSPVTVTAEADFARLVV
CCCCCCCCHHEEEEEEEECCCCCEEECCCEEECCCEEEEECCCCCEECC
>Mature Secondary Structure 
SDRCTLIVNPVSGSYSEAAVSAAMDALRRGGLAPRLLLTGGPDDAAAFAARLCAQEEHP
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCC
FVIAVGGDGTVNGVLNGLEPGRATLGYIPFGTANVLGRELGLRSAEDAVARIVRRETRSL
EEEEECCCCCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATGLLEGFGVRRRFFLMAGIGFDGQVVEGVRSDEKKRFGAGAYLFSAIRTLAAWDRRLLE
HHHHHHHCCHHEEEEEEECCCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHEEEE
VEVDGVAIACHGAVICNAARYGGPFTLAPGANLFHDGFRVVLIRDPSRWRYLSLALRVAA
EEECCEEEEECCEEEECHHHCCCCEEECCCCCEECCCEEEEEEECCCCHHHHHHHHHHHC
GRRAGGGPEVVSARRVAVGGNKPVQVDGDFICHSPVTVTAEADFARLVV
CCCCCCCCHHEEEEEEEECCCCCEEECCCEEECCCEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]