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The map label for this gene is ytfL [C]

Identifier: 39995959

GI number: 39995959

Start: 912183

End: 913517

Strand: Direct

Name: ytfL [C]

Synonym: GSU0853

Alternate gene names: 39995959

Gene position: 912183-913517 (Clockwise)

Preceding gene: 39995957

Following gene: 39995960

Centisome position: 23.92

GC content: 60.97

Gene sequence:

>1335_bases
ATGATTGAAGAATTATTGGTCATCTTTGTCCTGATTCTCGGCAATGGTTTTTTTGCCGGCTCGGAGCTTGCCATCATTTC
CGCCCGCAAGGGAAGAATTGCCCAGCTGGTCGAAGCCGGCGACTCCCGCGCCCAGATTGTTGAACGACTCCAGAATGATC
CGCACCGCTTTCTGGCCACGGTCCAGGTAGGGGTGACGGTGGTTGGCTCTCTTGCCTCCGCCGTGGGCGGCGCTGCGGCG
GTGCAATCGGTCAAACCGCTGCTGGAGGCGGTTCCCGTCGACTTCATCCGCCATGCGGCTGAGCCTCTGGCCATCGGCCT
GGCAGTCGTATTCATCTCCTATCTCTCCCTCATCTTCGGTGAACTGGTCCCCAAGACCGTGGGACTCCAGTATGCTGATC
AGATGGCGCTTCGCGTGGCCAAGCCGATCAGCTCCCTGGCAAAGGTCGCGGGAGTGGTGGTCAGCTTTCTCACCATTTCC
AACAAGGCAGTGCTCGCCATGATGGGGATCAAGGCCGAGGGGAGCCAGGCCTTCGTCACCCGCGAGGAGGTTCAGCACAT
CGTTGCCGAGGGGCACGAGGCGGGGGTGTTCAGCGCCACCGAGCAGGAGTACATCAGGAACATCTTCGATTTCACCCACA
CCTGCGTCCGTGAGGTGATGGTGCCGCGCACCCGCATGGTGGCGCTCGATCTGGCGCGTCCCCGGATGGAGCTGGTCCGG
GAGGTGCTGGACAACATGTATTCACGCTATCCGGTTTACCGCGAGAGCATCGAGAACGTCGTAGGCTTCATTCATGGCAA
GGATCTGCTGGGGAGGACCGTGACCGATCCGGAATTCGCCATGGAATCGATCGTCCGCCCTCCCTTCTATGTGCCCGAAG
GGAAAAAGGTCAACGAACTCCTCAAGGAGATGCAGCGGCTCAGGATTCACATGGCGCTGGTAGTCGACGAGTATGGCGGC
ATCAGCGGCCTGGTCACCACGGAGGACTTGCTGGAGGAGCTGGTGGGCGAGATCGAGGACGAACACGACATCGGCGAGCC
CGGGACCGTGCAGCGGCTGCCGGACGGCAGTCTGCTGGTGGACGCCCTCATGTCGATCGGAGACCTGGCAGACCTGCTCA
AGATCAAGCTGGAAGAGGATGTGCCCTATGACACCCTTGCTGGCCTCATTCTCGACCAGTTGGGACGCTTCCCCGAGCGG
GGCGAGACGGTTGAATGGGACCGCTTCAGCCTCATCTGCGAGGAGGTCAAGCAGACGGCGATCGTCAAGGTGCGCATCGT
GGAAAATCTGCCGCCCCAGGCGGGTGACGAACAGTACGGAACGGAGCACGAGTAG

Upstream 100 bases:

>100_bases
ACACTGATGTTACTATGCCAAATTTGTGCTACCATTCAACTGCTGAATGTGATGCAGTGCATGAATTCTTTCCATTCCCG
GGAGGTACGTTTCAACATCC

Downstream 100 bases:

>100_bases
GCATGGACCGGGGACACTTTTTCGCGCTGCTCGGTTTTCTGGCCGTTGCCCTCATGCTGTACCTCGTCTATGCCATTGTG
GCGCCGTTCCTGGCGCCGCT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MIEELLVIFVLILGNGFFAGSELAIISARKGRIAQLVEAGDSRAQIVERLQNDPHRFLATVQVGVTVVGSLASAVGGAAA
VQSVKPLLEAVPVDFIRHAAEPLAIGLAVVFISYLSLIFGELVPKTVGLQYADQMALRVAKPISSLAKVAGVVVSFLTIS
NKAVLAMMGIKAEGSQAFVTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREVMVPRTRMVALDLARPRMELVR
EVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPEFAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGG
ISGLVTTEDLLEELVGEIEDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFPER
GETVEWDRFSLICEEVKQTAIVKVRIVENLPPQAGDEQYGTEHE

Sequences:

>Translated_444_residues
MIEELLVIFVLILGNGFFAGSELAIISARKGRIAQLVEAGDSRAQIVERLQNDPHRFLATVQVGVTVVGSLASAVGGAAA
VQSVKPLLEAVPVDFIRHAAEPLAIGLAVVFISYLSLIFGELVPKTVGLQYADQMALRVAKPISSLAKVAGVVVSFLTIS
NKAVLAMMGIKAEGSQAFVTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREVMVPRTRMVALDLARPRMELVR
EVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPEFAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGG
ISGLVTTEDLLEELVGEIEDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFPER
GETVEWDRFSLICEEVKQTAIVKVRIVENLPPQAGDEQYGTEHE
>Mature_444_residues
MIEELLVIFVLILGNGFFAGSELAIISARKGRIAQLVEAGDSRAQIVERLQNDPHRFLATVQVGVTVVGSLASAVGGAAA
VQSVKPLLEAVPVDFIRHAAEPLAIGLAVVFISYLSLIFGELVPKTVGLQYADQMALRVAKPISSLAKVAGVVVSFLTIS
NKAVLAMMGIKAEGSQAFVTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREVMVPRTRMVALDLARPRMELVR
EVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPEFAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGG
ISGLVTTEDLLEELVGEIEDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFPER
GETVEWDRFSLICEEVKQTAIVKVRIVENLPPQAGDEQYGTEHE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=376, Percent_Identity=28.1914893617021, Blast_Score=195, Evalue=6e-50,
Organism=Escherichia coli, GI1790664, Length=413, Percent_Identity=25.6658595641646, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=26.1904761904762, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786879, Length=287, Percent_Identity=32.7526132404181, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082033, Length=385, Percent_Identity=25.1948051948052, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788119, Length=280, Percent_Identity=25.3571428571429, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48841; Mature: 48841

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEELLVIFVLILGNGFFAGSELAIISARKGRIAQLVEAGDSRAQIVERLQNDPHRFLAT
CHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
VQVGVTVVGSLASAVGGAAAVQSVKPLLEAVPVDFIRHAAEPLAIGLAVVFISYLSLIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ELVPKTVGLQYADQMALRVAKPISSLAKVAGVVVSFLTISNKAVLAMMGIKAEGSQAFVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
REEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREVMVPRTRMVALDLARPRMELVR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
EVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPEFAMESIVRPPFYVPEGKKVNEL
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHH
LKEMQRLRIHMALVVDEYGGISGLVTTEDLLEELVGEIEDEHDIGEPGTVQRLPDGSLLV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
DALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFPERGETVEWDRFSLICEEVKQTA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IVKVRIVENLPPQAGDEQYGTEHE
HEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIEELLVIFVLILGNGFFAGSELAIISARKGRIAQLVEAGDSRAQIVERLQNDPHRFLAT
CHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
VQVGVTVVGSLASAVGGAAAVQSVKPLLEAVPVDFIRHAAEPLAIGLAVVFISYLSLIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ELVPKTVGLQYADQMALRVAKPISSLAKVAGVVVSFLTISNKAVLAMMGIKAEGSQAFVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
REEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREVMVPRTRMVALDLARPRMELVR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
EVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPEFAMESIVRPPFYVPEGKKVNEL
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHH
LKEMQRLRIHMALVVDEYGGISGLVTTEDLLEELVGEIEDEHDIGEPGTVQRLPDGSLLV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
DALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFPERGETVEWDRFSLICEEVKQTA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IVKVRIVENLPPQAGDEQYGTEHE
HEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]