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The map label for this gene is atoC [H]

Identifier: 39995882

GI number: 39995882

Start: 833267

End: 834664

Strand: Reverse

Name: atoC [H]

Synonym: GSU0776

Alternate gene names: 39995882

Gene position: 834664-833267 (Counterclockwise)

Preceding gene: 39995895

Following gene: 39995881

Centisome position: 21.88

GC content: 64.81

Gene sequence:

>1398_bases
ATGCTCAAGGCGAAAATACTCATTTGCGACGATGAAGAAGGAATCCGGCGCTACCTTCAGAAGATGTTCCAGGCCAAGGA
GTTCGAGGTGGAGACCTTTGCCGACGGCACGAGCCTGCTGGCCCGGATCGAGGCCGGCACCGACGGCGATGCGGACATCC
TGCTCCAGGATGTGCGGATGCCCGACATGGACGGCATCGAAGTGCTCAAGCGGGTCAAGAAGCTCCGCCCCTCCCTGCCG
GTGGTGGTCATGACCGCCTTCGGCACCATCGATTCGGCCGTTGACGCCATCAAGCTGGGGGCCTACGACTACGTCACCAA
GCCGTTCCCGCGCGAGAAGATCCTCGGCGTCATCGACAACGCCCTTGAGCTGGACCTGCTCATGAAGGAGAACAAGGCCC
TCAAGGAGGAGCTGGCGCGGCCCGACACCCCCGACAACATCATCTTTACCAGCGCCAAGTTCCGGGAGGTCTACGAACTC
ACCCTCCAGGTGGCCGGCAGCGACGCCAACATCCTGATTCTCGGCGAATCCGGCACCGGCAAGGAGCTGATCGCCGGCGC
CGTCCACTACAACAGCCCCCGCCGGGGGCGGCGTTTCCTCTCCATCAACTGCGCCGCCCTGTCCGACACGCTGCTCGAAA
GCCAGCTCTTCGGCCACGTGCGCGGCGCCTTCACCGGCGCCATCACCACCCAGAAGGGGCTTCTGGAGGAGGCCGACGGC
GGCACCCTCTTCCTGGACGAGATCGGCGACGTGTCGGCCGCGGTCCAGGCGAAGCTGCTCCGGGTTATCCAGGAGCGTGA
CTTCATCCCGGTGGGCGCCACCAAGGCCAAGAACGTGGATATCCGCTTCGTGGCCGCCACCAACAAGGATCTGGCCAAAG
AAGTACGGGAGGGGCGCTTCCGCGAAGACCTCTACTACCGCCTGAACGTCATCACCATCAACCTCCCTCCGCTGCGGGAG
CGGACCGAGGACATCATTCCCCTGGCCGAGCATTTCCTCCAGAAGTACTCCCGTCGCGTCAGGAAAGAGCTGAAGGGAAT
CTCGCCCGAGGCGGCCCAGGTACTGCAGGCCTACCACTGGCCCGGCAACGTCCGCGAGCTGGAGAACGTGGTGGAGCGGG
CCGCCATCCTCGCCCGGGGGGAGTTCGTGACCCCCGACGTCCTTCCCATGTACCGGCAGGCAGCAGGAGCCCCCGCCCCT
ATCGCCCCGCCGAAGGAAGACCGTCTTATCTCCCTTGAGGTGATCGAGAAGGAGCATATCGAGCGGGTCCTCCACCAGAC
CGGCTGGCACAAGAGCCGGTCCGCCGAGATCCTGGGCATCTCGCGCAAGACCCTCGACCGCAAGATCGTCGAGTACGCCC
TGACCCTCCCGGGAGGCGTCCCGGCCGACGACGAATGA

Upstream 100 bases:

>100_bases
TTCTGGCCGCATCTGTATCATTTTGTCCATGTAGACACGTCTACGAAGACCACAGGGTTACCTCTCACACATCCCCATGA
ACAAAGGAATCCGGGCAACG

Downstream 100 bases:

>100_bases
AGCCACTCCGCTTCCCCATACGTCTCAAGCTGACCTTTGCGACCCTGATCCCCCTCTTCGTCGCCACCAGCATCTGCTGG
CTCATCGGCGTCTACATCAT

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MLKAKILICDDEEGIRRYLQKMFQAKEFEVETFADGTSLLARIEAGTDGDADILLQDVRMPDMDGIEVLKRVKKLRPSLP
VVVMTAFGTIDSAVDAIKLGAYDYVTKPFPREKILGVIDNALELDLLMKENKALKEELARPDTPDNIIFTSAKFREVYEL
TLQVAGSDANILILGESGTGKELIAGAVHYNSPRRGRRFLSINCAALSDTLLESQLFGHVRGAFTGAITTQKGLLEEADG
GTLFLDEIGDVSAAVQAKLLRVIQERDFIPVGATKAKNVDIRFVAATNKDLAKEVREGRFREDLYYRLNVITINLPPLRE
RTEDIIPLAEHFLQKYSRRVRKELKGISPEAAQVLQAYHWPGNVRELENVVERAAILARGEFVTPDVLPMYRQAAGAPAP
IAPPKEDRLISLEVIEKEHIERVLHQTGWHKSRSAEILGISRKTLDRKIVEYALTLPGGVPADDE

Sequences:

>Translated_465_residues
MLKAKILICDDEEGIRRYLQKMFQAKEFEVETFADGTSLLARIEAGTDGDADILLQDVRMPDMDGIEVLKRVKKLRPSLP
VVVMTAFGTIDSAVDAIKLGAYDYVTKPFPREKILGVIDNALELDLLMKENKALKEELARPDTPDNIIFTSAKFREVYEL
TLQVAGSDANILILGESGTGKELIAGAVHYNSPRRGRRFLSINCAALSDTLLESQLFGHVRGAFTGAITTQKGLLEEADG
GTLFLDEIGDVSAAVQAKLLRVIQERDFIPVGATKAKNVDIRFVAATNKDLAKEVREGRFREDLYYRLNVITINLPPLRE
RTEDIIPLAEHFLQKYSRRVRKELKGISPEAAQVLQAYHWPGNVRELENVVERAAILARGEFVTPDVLPMYRQAAGAPAP
IAPPKEDRLISLEVIEKEHIERVLHQTGWHKSRSAEILGISRKTLDRKIVEYALTLPGGVPADDE
>Mature_465_residues
MLKAKILICDDEEGIRRYLQKMFQAKEFEVETFADGTSLLARIEAGTDGDADILLQDVRMPDMDGIEVLKRVKKLRPSLP
VVVMTAFGTIDSAVDAIKLGAYDYVTKPFPREKILGVIDNALELDLLMKENKALKEELARPDTPDNIIFTSAKFREVYEL
TLQVAGSDANILILGESGTGKELIAGAVHYNSPRRGRRFLSINCAALSDTLLESQLFGHVRGAFTGAITTQKGLLEEADG
GTLFLDEIGDVSAAVQAKLLRVIQERDFIPVGATKAKNVDIRFVAATNKDLAKEVREGRFREDLYYRLNVITINLPPLRE
RTEDIIPLAEHFLQKYSRRVRKELKGISPEAAQVLQAYHWPGNVRELENVVERAAILARGEFVTPDVLPMYRQAAGAPAP
IAPPKEDRLISLEVIEKEHIERVLHQTGWHKSRSAEILGISRKTLDRKIVEYALTLPGGVPADDE

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=463, Percent_Identity=44.2764578833693, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=43.6936936936937, Blast_Score=355, Evalue=4e-99,
Organism=Escherichia coli, GI1790299, Length=475, Percent_Identity=38.5263157894737, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1788905, Length=384, Percent_Identity=40.3645833333333, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI87082117, Length=254, Percent_Identity=51.5748031496063, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789233, Length=327, Percent_Identity=43.1192660550459, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789087, Length=349, Percent_Identity=45.2722063037249, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082152, Length=299, Percent_Identity=45.4849498327759, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=41.3680781758958, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1786524, Length=330, Percent_Identity=38.4848484848485, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787583, Length=315, Percent_Identity=39.3650793650794, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=39.8268398268398, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=31, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=111, Percent_Identity=31.5315315315315, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790860, Length=113, Percent_Identity=34.5132743362832, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51802; Mature: 51802

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAKILICDDEEGIRRYLQKMFQAKEFEVETFADGTSLLARIEAGTDGDADILLQDVRM
CCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHEEEECCCCCCHHHHEECCCC
PDMDGIEVLKRVKKLRPSLPVVVMTAFGTIDSAVDAIKLGAYDYVTKPFPREKILGVIDN
CCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ALELDLLMKENKALKEELARPDTPDNIIFTSAKFREVYELTLQVAGSDANILILGESGTG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHEEECCCCEEEEEECCCCC
KELIAGAVHYNSPRRGRRFLSINCAALSDTLLESQLFGHVRGAFTGAITTQKGLLEEADG
HHHHEEHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCC
GTLFLDEIGDVSAAVQAKLLRVIQERDFIPVGATKAKNVDIRFVAATNKDLAKEVREGRF
CEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCC
REDLYYRLNVITINLPPLRERTEDIIPLAEHFLQKYSRRVRKELKGISPEAAQVLQAYHW
HHCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PGNVRELENVVERAAILARGEFVTPDVLPMYRQAAGAPAPIAPPKEDRLISLEVIEKEHI
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHH
ERVLHQTGWHKSRSAEILGISRKTLDRKIVEYALTLPGGVPADDE
HHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKAKILICDDEEGIRRYLQKMFQAKEFEVETFADGTSLLARIEAGTDGDADILLQDVRM
CCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHEEEECCCCCCHHHHEECCCC
PDMDGIEVLKRVKKLRPSLPVVVMTAFGTIDSAVDAIKLGAYDYVTKPFPREKILGVIDN
CCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ALELDLLMKENKALKEELARPDTPDNIIFTSAKFREVYELTLQVAGSDANILILGESGTG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHEEECCCCEEEEEECCCCC
KELIAGAVHYNSPRRGRRFLSINCAALSDTLLESQLFGHVRGAFTGAITTQKGLLEEADG
HHHHEEHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCC
GTLFLDEIGDVSAAVQAKLLRVIQERDFIPVGATKAKNVDIRFVAATNKDLAKEVREGRF
CEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCC
REDLYYRLNVITINLPPLRERTEDIIPLAEHFLQKYSRRVRKELKGISPEAAQVLQAYHW
HHCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PGNVRELENVVERAAILARGEFVTPDVLPMYRQAAGAPAPIAPPKEDRLISLEVIEKEHI
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHH
ERVLHQTGWHKSRSAEILGISRKTLDRKIVEYALTLPGGVPADDE
HHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]