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The map label for this gene is clpB

Identifier: 39995764

GI number: 39995764

Start: 693347

End: 695944

Strand: Direct

Name: clpB

Synonym: GSU0658

Alternate gene names: 39995764

Gene position: 693347-695944 (Clockwise)

Preceding gene: 39995763

Following gene: 39995765

Centisome position: 18.18

GC content: 60.59

Gene sequence:

>2598_bases
ATGATCAGACCTGAGAAAATGACCATAAAGACCCAGGAAGCCTTGGCCGGAGCCCAGCAACTGGCCGCACGGCAGGGTAA
TGGCTCCATCGAGCCGGAGCACCTTCTGGTCTCGCTCCTTGAGCAGGAAGGGGGGCTCATTGCCCCGATCATTCAGAAAG
TGGGAGGTGCACCGGCCGCACTGCGGAGCGCTGCGGATGTGTTGGTGAAAAGGCTTCCCCAGGTGAGCGGGGCCACGGCC
CAGGCCTATCTGTCGCCGGCCCTCAACCGGATTCTCGACGCGGCCCAGCGCGAAGCCGATACCATGAAGGATGAATTCGT
CTCCACCGAGCATCTCCTCCTCGGCTTCTTTGCCGACCGGCAGTGCGCGGCAGCCCGGGCGCTTCTTGATGCAGGAGTCA
GCCGGGATAACGTCCTGGCGGCCCTGATGGAGATCCGCGGGGGAGAGCGGGTTACCGACCAGAACCCCGAGGATACTTAT
CAGGCCTTGGCCAAGTATGCCCGCGACCTGACCGATTTGGCCCGTCAGGGAAAGCTCGACCCGGTTATCGGCCGCGACGA
CGAGATCCGGCGGGTGCTCCAGGTGCTGTCCCGGCGAACAAAGAACAACCCGGTCCTGATCGGTGAGCCTGGGGTGGGAA
AGACCGCCATCGTGGAGGGGCTTGCGCAGCGGATCGTCTCCGGTGATGTGCCTGAGACCCTCAAGGATAAGCGGCTCGTT
GCTCTCGATATGGGTGCGCTCATTGCCGGTGCCAAGTACCGCGGTGAATTCGAGGAGCGCCTCAAGGCGGTCATCAGGGA
GGTGGCCAAGTCTGAGGGCAAGGTGATCCTGTTCATCGACGAGCTTCACACCTTGGTCGGGGCCGGTGCTGCCGAGGGGG
CCATGGATGCGTCCAACATGCTCAAACCGGCGCTTGCCCGGGGAGAGCTCCACTGCATCGGTGCCACGACGCTCAATGAA
TATCGCAAGTACATCGAGAAGGACGCGGCTCTTGAACGGCGGTTCCAGCAGGTCTATACCGGCGAACCGTCGGTTGAGGA
CACTATCGCGATCCTGCGCGGGCTCAAGGAAAAGTACGAGAACTATCACGGCATAAGGATCAAGGACAGCGCCATCATTG
CGGCCGCCACCCTGTCGGACCGCTACATCACCGACCGCTTTCTCCCCGATAAGGCAATCGACCTGATCGATGAGGCCGCC
TCACGTTTGAGGATCGAGATCGATTCCATGCCTACGGAAATCGATGAGGTTGAGCGGAGGATCATTCAACTGGAGATCGA
AAAACAGGCCTTGCTGCGGGAGAGCCAAGATCCTCACTCTCTGGAGCGGCTGAAAAAACTCGCCGACGAACTGGAGGAAC
TCAAGGCTAAGTCGGCCGAGCTCAAGGGGCACTGGCAGCGGGAGAAGGATATCATCGGCCGGGTAAGTTCGCTCAGGCAA
CGGCTCGAAGAGAAGAGGGAAGAAGCGAAAAAGGCCGAGCGCGAAGGCAATCTGGCCCGGACGGCTGAGATCCGCTACGG
TGAGATCCCGGCTATCGAGAAAGAAATCGCCGACAGGAGCGCGGAGCTGGAGGATATCCGCAAGGAAGGAAAGATGCTGC
CGGAGGAAGTGGATGGCGAGCTGGTGGCCGAGATCGTTTCCCGGTGGACCGGTATTCCGGTTTCCCGCATGATGGAGGGC
GAGGCGGACAAGCTGGTGCATATGGAGGACCGGCTGATAACCCGGGTCGTCGGCCAGGATGAGGCACTCGTCCTGGTGGC
AAACGCCATCCGCCGGGCCCGGTCCGGTCTCTCGGACCCCAATCGCCCTATTGGCTCGTTCCTGTTTCTGGGGCCCACCG
GTGTCGGCAAAACCGAAACCGCCAAGGCCCTGGCGGAGTTCCTGTTCAACGACGACCAGGCCATCGTTCGCATCGACATG
AGCGAGTATCAGGAAAAGCACACCGTTGCCCGACTCATCGGCGCTCCGCCGGGCTATGTGGGATACGAAGAAGGGGGGCA
GCTTACCGAGGCGGTCAGGCGGCGACCCTATTCCATCGTCCTCTTCGACGAGATCGAAAAGGCTCATCCGGAGGTCTTCA
ATGTGCTCCTCCAGGTGCTGGACGACGGGCGGCTCACCGATGGGCAGGGGCGTACTGTCGATTTCCGCAACACGGTCATC
ATCATGACGAGCAACCTTGGTTCCCAATGGATTCAGCAGTACGGTTCCAGCGACTACGCACGCATGAAGGCCATGGTCAC
CGAGACGCTCAAGGAGGGATTCAAACCAGAATTCCTCAACCGCATCGACGAAATCGTGATCTATCATGCGCTTCCCCTTG
AGCAGATCAAGAAGATCGTCGATATCCAGGTGGAATGTCTGAAGCAGCGACTCGCTGATCGGCGCATCGTCCTTGAACTG
AGCGACAAGGCCCGGGAATACCTGAGCCGCGAGGGCTATGACCCCGCCTACGGTGCCCGGCCCCTCAAGCGGACGATCCA
GCGAAAGATCCAAGACCCGCTGGCCCTGGCGCTTCTGGAAGGAAAGTTTCAGGAAGGGGATACGGTCAGGGTCGACCTGT
CCGTGTCGGGGGAGGAGCTTGTCATCACGAAGAAATAG

Upstream 100 bases:

>100_bases
GTCAGCATCCATCCTCCGCCGAAAACCTTCTCTTACCCGTCCTTGACTTCCTCCCCGGGCGTGCCTATGTTTTCCTTGAA
ACAGGAAAGGAGAGCGCCCA

Downstream 100 bases:

>100_bases
TTTCGCCACCGATTAGAGCGCATCAGCGGGCTTCATTCCTGAAGCCCGCTTTTTTTGTTTCAGGGTGCCTTGAGAGGCGT
TACTATTGGCAGTACCTGAC

Product: ClpB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAALRSAADVLVKRLPQVSGATA
QAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADRQCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTY
QALAKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYENYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERRIIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQ
RLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGELVAEIVSRWTGIPVSRMMEG
EADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDM
SEYQEKHTVARLIGAPPGYVGYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
IMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIVDIQVECLKQRLADRRIVLEL
SDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLEGKFQEGDTVRVDLSVSGEELVITKK

Sequences:

>Translated_865_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAALRSAADVLVKRLPQVSGATA
QAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADRQCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTY
QALAKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYENYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERRIIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQ
RLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGELVAEIVSRWTGIPVSRMMEG
EADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDM
SEYQEKHTVARLIGAPPGYVGYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
IMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIVDIQVECLKQRLADRRIVLEL
SDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLEGKFQEGDTVRVDLSVSGEELVITKK
>Mature_865_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAALRSAADVLVKRLPQVSGATA
QAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADRQCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTY
QALAKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYENYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERRIIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQ
RLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGELVAEIVSRWTGIPVSRMMEG
EADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDM
SEYQEKHTVARLIGAPPGYVGYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
IMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIVDIQVECLKQRLADRRIVLEL
SDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLEGKFQEGDTVRVDLSVSGEELVITKK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family

Homologues:

Organism=Homo sapiens, GI13540606, Length=324, Percent_Identity=36.1111111111111, Blast_Score=219, Evalue=1e-56,
Organism=Escherichia coli, GI1788943, Length=854, Percent_Identity=58.7822014051522, Blast_Score=995, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=328, Percent_Identity=45.1219512195122, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=53.6723163841808, Blast_Score=760, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=861, Percent_Identity=43.7862950058072, Blast_Score=682, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CLPB_GEOSL (Q74FF1)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951715.1
- ProteinModelPortal:   Q74FF1
- GeneID:   2685505
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0658
- NMPDR:   fig|243231.1.peg.653
- TIGR:   GSU0658
- HOGENOM:   HBG413133
- OMA:   NSLARMI
- ProtClustDB:   CLSK827978
- BioCyc:   GSUL243231:GSU_0658-MONOMER
- GO:   GO:0005737
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- Gene3D:   G3DSA:1.10.1780.10
- PRINTS:   PR00300
- SMART:   SM00382
- TIGRFAMs:   TIGR03346

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small

EC number: NA

Molecular weight: Translated: 96458; Mature: 96458

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00870 CLPAB_1; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAA
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEHHHHHHCCCCHHH
LRSAADVLVKRLPQVSGATAQAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTYQALAKYARDLTDLARQGKLD
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLV
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEE
ALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNM
EEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHCIGATTLNEYRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYE
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
NYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAASRLRIEIDSMPTEIDEVERR
CCCCEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
IIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHH
LVAEIVSRWTGIPVSRMMEGEADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDP
HHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
NRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMSEYQEKHTVARLIGAPPGYV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
CCCCCCHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
IMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIV
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
DIQVECLKQRLADRRIVLELSDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLE
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
GKFQEGDTVRVDLSVSGEELVITKK
CCCCCCCEEEEEEEECCCEEEEECC
>Mature Secondary Structure
MIRPEKMTIKTQEALAGAQQLAARQGNGSIEPEHLLVSLLEQEGGLIAPIIQKVGGAPAA
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEHHHHHHCCCCHHH
LRSAADVLVKRLPQVSGATAQAYLSPALNRILDAAQREADTMKDEFVSTEHLLLGFFADR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QCAAARALLDAGVSRDNVLAALMEIRGGERVTDQNPEDTYQALAKYARDLTDLARQGKLD
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPETLKDKRLV
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEE
ALDMGALIAGAKYRGEFEERLKAVIREVAKSEGKVILFIDELHTLVGAGAAEGAMDASNM
EEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHCIGATTLNEYRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYE
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
NYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAASRLRIEIDSMPTEIDEVERR
CCCCEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
IIQLEIEKQALLRESQDPHSLERLKKLADELEELKAKSAELKGHWQREKDIIGRVSSLRQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEEKREEAKKAEREGNLARTAEIRYGEIPAIEKEIADRSAELEDIRKEGKMLPEEVDGE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHH
LVAEIVSRWTGIPVSRMMEGEADKLVHMEDRLITRVVGQDEALVLVANAIRRARSGLSDP
HHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
NRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMSEYQEKHTVARLIGAPPGYV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRRPYSIVLFDEIEKAHPEVFNVLLQVLDDGRLTDGQGRTVDFRNTVI
CCCCCCHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
IMTSNLGSQWIQQYGSSDYARMKAMVTETLKEGFKPEFLNRIDEIVIYHALPLEQIKKIV
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
DIQVECLKQRLADRRIVLELSDKAREYLSREGYDPAYGARPLKRTIQRKIQDPLALALLE
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
GKFQEGDTVRVDLSVSGEELVITKK
CCCCCCCEEEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA