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The map label for this gene is nuoC

Identifier: 39995449

GI number: 39995449

Start: 368755

End: 369243

Strand: Direct

Name: nuoC

Synonym: GSU0340

Alternate gene names: 39995449

Gene position: 368755-369243 (Clockwise)

Preceding gene: 39995448

Following gene: 39995450

Centisome position: 9.67

GC content: 53.37

Gene sequence:

>489_bases
ATGGCTGAGAACAATCGTGCAGTTATAAAACTTAAGGAAAAATTTGCCGCGTCAATCCTTGATGTAAGGGAATTCCGCGG
CGAGGTTACGGTTACGGTGGCACGTGAGAAGGTCGTGGATATCTGCCGTTTCCTGAAAGAGTCGTTACAGTACAACCTCT
GCACAGACGTGACGGCTGTTGACTATCTTGGGAAGCAGGAGCCGCGCTTCATGGTGGTGTATAACCTGTATTCGATTCCC
AATAAGGATCGGCTCAGACTCAAGGCTGGCGTGCCTGATGCCGACTGTTCGATCGATACGGTGTCATGTGTCTGGAACTC
AGCTAATTGGCTGGAGCGTGAAGTGTACGACCTCATGGGTGTGCAATTCAACAACCACCCTGACCTGCGTCGTATCCTGA
TGACCGACGACTGGGTCGGCCACCCGCTCCGCAAGGATTATCCCCTGCAGGGGCCTGATCGTGAGCCCTACAAGGGCCGG
CTTTCCTGA

Upstream 100 bases:

>100_bases
TTATGAAGGACAAGAACTCGTTTGGCTCGACCATAGGGCTCGGCGAGCGCCTTGAGTCCGCAGCGTGACCATCTCACTTA
AGTAAGGGGAACGAACGGTG

Downstream 100 bases:

>100_bases
TTTATCGGCTTGCTGAGAGAAAATAACTCCACAGGGATACAGAGGCGCACAAATGGCTAGCACTGAGATAATGACAGTCA
ATATGGGACCGCAGCACCCG

Product: NADH dehydrogenase I subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAENNRAVIKLKEKFAASILDVREFRGEVTVTVAREKVVDICRFLKESLQYNLCTDVTAVDYLGKQEPRFMVVYNLYSIP
NKDRLRLKAGVPDADCSIDTVSCVWNSANWLEREVYDLMGVQFNNHPDLRRILMTDDWVGHPLRKDYPLQGPDREPYKGR
LS

Sequences:

>Translated_162_residues
MAENNRAVIKLKEKFAASILDVREFRGEVTVTVAREKVVDICRFLKESLQYNLCTDVTAVDYLGKQEPRFMVVYNLYSIP
NKDRLRLKAGVPDADCSIDTVSCVWNSANWLEREVYDLMGVQFNNHPDLRRILMTDDWVGHPLRKDYPLQGPDREPYKGR
LS
>Mature_161_residues
AENNRAVIKLKEKFAASILDVREFRGEVTVTVAREKVVDICRFLKESLQYNLCTDVTAVDYLGKQEPRFMVVYNLYSIPN
KDRLRLKAGVPDADCSIDTVSCVWNSANWLEREVYDLMGVQFNNHPDLRRILMTDDWVGHPLRKDYPLQGPDREPYKGRL
S

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=126, Percent_Identity=42.0634920634921, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI145693162, Length=157, Percent_Identity=33.7579617834395, Blast_Score=97, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=126, Percent_Identity=42.8571428571429, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=126, Percent_Identity=42.8571428571429, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24656494, Length=126, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_GEOSL (Q74GA6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951400.1
- ProteinModelPortal:   Q74GA6
- SMR:   Q74GA6
- GeneID:   2686824
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0340
- NMPDR:   fig|243231.1.peg.338
- TIGR:   GSU0340
- HOGENOM:   HBG727675
- OMA:   REPYKGR
- ProtClustDB:   CLSK827763
- BioCyc:   GSUL243231:GSU_0340-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 18784; Mature: 18653

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENNRAVIKLKEKFAASILDVREFRGEVTVTVAREKVVDICRFLKESLQYNLCTDVTAV
CCCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHH
DYLGKQEPRFMVVYNLYSIPNKDRLRLKAGVPDADCSIDTVSCVWNSANWLEREVYDLMG
HHCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCEEHEEEECCCHHHHHHHHHHHC
VQFNNHPDLRRILMTDDWVGHPLRKDYPLQGPDREPYKGRLS
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AENNRAVIKLKEKFAASILDVREFRGEVTVTVAREKVVDICRFLKESLQYNLCTDVTAV
CCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHH
DYLGKQEPRFMVVYNLYSIPNKDRLRLKAGVPDADCSIDTVSCVWNSANWLEREVYDLMG
HHCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCEEHEEEECCCHHHHHHHHHHHC
VQFNNHPDLRRILMTDDWVGHPLRKDYPLQGPDREPYKGRLS
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA