Click here to switch to the map view.

The map label for this gene is lldP [C]

Identifier: 39995336

GI number: 39995336

Start: 232930

End: 234558

Strand: Direct

Name: lldP [C]

Synonym: GSU0226

Alternate gene names: 39995336

Gene position: 232930-234558 (Clockwise)

Preceding gene: 39995335

Following gene: 39995337

Centisome position: 6.11

GC content: 63.78

Gene sequence:

>1629_bases
ATGTTACTGGAGGTTATTCCCTTGACCCTGCCGTTGCTGCTGACCCTGCTCCCCATCGTAGTCATCCTCGTCATGCTTCT
GGTGTTCCGCAAGGCCGCCGATGTGAGCGGCATCATCGGCTGGCTCGCCATCTCGGTGGTGGCCTGGCTCGGATTCCAGA
CCGCGCCGGAAGTCATTCTCCGCTCTACCGCCGCCGGCTTTATCCGCTCCTTTTCCGTGTCACTCATCGTGGCCACGTCG
CTTCTGCAGATGGCGCTCATGGAGAAGACCGGCGCGCTCCGGCGGATCACCATCTTCATCAGGACCATTGCCAGCGACAA
CCGGGCCGTGCAGATCATGATGATCAACATCGGCTTCGGGACCCTCATGGTGGCGGTGGGGGCCACGCCGGTCTCGATCC
TGCCGCCGATCCTGCTGGCCATGGGCTACTCCACCTACGTGGCCATCGCCCTGCCGGCAATCGGCTACGACTCGCTCTGC
ACCTATGCGCTCCTGGGCGCGCCCATCGTGGTCTTCGTGGATATCGCCAACAGTTTTCTCGGCAAGGGGAACGAGATCGC
CCTTCACCAGGCCGGCATGGTCTTTTACATGTTCCTTCCGGTGGTTTCCACCATGATCGGGTTCTGCATGCTCTGGATCG
TGGGGAAGTGGCAGGCGATCCGGGACGGGTGGCTCCCCTGCCTCCTCACCGGCGCGGTCATCGGCGTGGTGGCCCGCTTC
ACCAATCAGTACGACAACCTGGTGGTGCTGACGGGCGTCCTCTGCGGCATCGCCGTCATTGCCGCCATGGCGGCCTACCT
GGTTGTCACCGGCGGCAAAGTGATCGACCGCTCCCTCCTCTCCGCCGAGGAGCGGGAATTCGCCGCAGCCATGCCCCTCT
GGCGGGCTTTCATGCCGTGGACCCTCCTCGTTATCCTTATTCTCGTCCTGAACGTTCCCCAGGACCTTTTCTCTTGGCTC
TACCGGACCATGAAACTGCCCATCGCGGGCCTTACGGCCGACGGCAAGCCCCTGGACACGCGGGCCCTGTGGCAGGCCTA
CACCTGGATCCTGGTCAGCACCATCCTGGCCGTGCCGTTCCTGAAGCCCACGGGGGAGCAGCTCCGGGAAACAGTCCGGA
CCTGGGTCCGGCGGGCACCCCGGCCGGTGTTCGCGGCAGCCGTTTTCTTTGCCATCGGCGAGATAATGAACATGGCGGGC
TACGATATGGCGGCGGGCCGGTTCGTTGTGCCGAGCATGGTCACGGTGCTGGCCGATTCCTCGGCGCTGGCCTTCCAGGG
GATGTACGGGGAGGTGGTGGCGTTCATCGGGCTTTTCGGCGGGTTCATCACCGGCAGCGAGGCATCGACCATCGCCATGT
TCGCCAAGTACACCATGACCACGGCCAAGAACCTGGACATGCCGCTGTCGGGGCTGATCATCGTCACGGCGGGGCTCGCC
TTCGGCGGTGGGCTTGCCAGCGTCATCTCGCCCGCCAAGCTCCAGAACGCTGCTGCAGCCATCGACAGGATCGGCGAGGA
GGGGAAGGTGATCCGCATCGCCTTTGTCTTCGCACTCCTGCTGACCCTGGTCACCTCCCTGTTCGTGGTGGTTCTGCTCA
CGGTCAACGGCATGGGGAGAGTTTCGTGA

Upstream 100 bases:

>100_bases
GGGTGGGCGGTCTTCCGTGGGGGTTGCCTCGCCGGCGGTGCCGGGTGTATGCTGTGCGACGGTCTGTCGATGCACCGCCC
CCGACTCCTGAGGGGCCGGT

Downstream 100 bases:

>100_bases
GCCCGGAGGGGCGGGGATGAGGGCGGTCGAGCTCTTCTGCGGCATCGGCGGTTTCGCCGCCGCGGTGGAGGGGACGGGCG
TCCGCGTGGTGGCGGCTATG

Product: L-lactate permease

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: L-Lactate Permease Family Protein; L-Lactate Transport; L-Lactate Permease-Like Protein

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MLLEVIPLTLPLLLTLLPIVVILVMLLVFRKAADVSGIIGWLAISVVAWLGFQTAPEVILRSTAAGFIRSFSVSLIVATS
LLQMALMEKTGALRRITIFIRTIASDNRAVQIMMINIGFGTLMVAVGATPVSILPPILLAMGYSTYVAIALPAIGYDSLC
TYALLGAPIVVFVDIANSFLGKGNEIALHQAGMVFYMFLPVVSTMIGFCMLWIVGKWQAIRDGWLPCLLTGAVIGVVARF
TNQYDNLVVLTGVLCGIAVIAAMAAYLVVTGGKVIDRSLLSAEEREFAAAMPLWRAFMPWTLLVILILVLNVPQDLFSWL
YRTMKLPIAGLTADGKPLDTRALWQAYTWILVSTILAVPFLKPTGEQLRETVRTWVRRAPRPVFAAAVFFAIGEIMNMAG
YDMAAGRFVVPSMVTVLADSSALAFQGMYGEVVAFIGLFGGFITGSEASTIAMFAKYTMTTAKNLDMPLSGLIIVTAGLA
FGGGLASVISPAKLQNAAAAIDRIGEEGKVIRIAFVFALLLTLVTSLFVVVLLTVNGMGRVS

Sequences:

>Translated_542_residues
MLLEVIPLTLPLLLTLLPIVVILVMLLVFRKAADVSGIIGWLAISVVAWLGFQTAPEVILRSTAAGFIRSFSVSLIVATS
LLQMALMEKTGALRRITIFIRTIASDNRAVQIMMINIGFGTLMVAVGATPVSILPPILLAMGYSTYVAIALPAIGYDSLC
TYALLGAPIVVFVDIANSFLGKGNEIALHQAGMVFYMFLPVVSTMIGFCMLWIVGKWQAIRDGWLPCLLTGAVIGVVARF
TNQYDNLVVLTGVLCGIAVIAAMAAYLVVTGGKVIDRSLLSAEEREFAAAMPLWRAFMPWTLLVILILVLNVPQDLFSWL
YRTMKLPIAGLTADGKPLDTRALWQAYTWILVSTILAVPFLKPTGEQLRETVRTWVRRAPRPVFAAAVFFAIGEIMNMAG
YDMAAGRFVVPSMVTVLADSSALAFQGMYGEVVAFIGLFGGFITGSEASTIAMFAKYTMTTAKNLDMPLSGLIIVTAGLA
FGGGLASVISPAKLQNAAAAIDRIGEEGKVIRIAFVFALLLTLVTSLFVVVLLTVNGMGRVS
>Mature_542_residues
MLLEVIPLTLPLLLTLLPIVVILVMLLVFRKAADVSGIIGWLAISVVAWLGFQTAPEVILRSTAAGFIRSFSVSLIVATS
LLQMALMEKTGALRRITIFIRTIASDNRAVQIMMINIGFGTLMVAVGATPVSILPPILLAMGYSTYVAIALPAIGYDSLC
TYALLGAPIVVFVDIANSFLGKGNEIALHQAGMVFYMFLPVVSTMIGFCMLWIVGKWQAIRDGWLPCLLTGAVIGVVARF
TNQYDNLVVLTGVLCGIAVIAAMAAYLVVTGGKVIDRSLLSAEEREFAAAMPLWRAFMPWTLLVILILVLNVPQDLFSWL
YRTMKLPIAGLTADGKPLDTRALWQAYTWILVSTILAVPFLKPTGEQLRETVRTWVRRAPRPVFAAAVFFAIGEIMNMAG
YDMAAGRFVVPSMVTVLADSSALAFQGMYGEVVAFIGLFGGFITGSEASTIAMFAKYTMTTAKNLDMPLSGLIIVTAGLA
FGGGLASVISPAKLQNAAAAIDRIGEEGKVIRIAFVFALLLTLVTSLFVVVLLTVNGMGRVS

Specific function: Transports L-Lactate Across The Membrane. Can Also Transport D-Lactate And Glycolate. Seems To Be Driven By A Proton Motive Force. [C]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58163; Mature: 58163

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEVIPLTLPLLLTLLPIVVILVMLLVFRKAADVSGIIGWLAISVVAWLGFQTAPEVIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RSTAAGFIRSFSVSLIVATSLLQMALMEKTGALRRITIFIRTIASDNRAVQIMMINIGFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECHH
TLMVAVGATPVSILPPILLAMGYSTYVAIALPAIGYDSLCTYALLGAPIVVFVDIANSFL
HHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHC
GKGNEIALHQAGMVFYMFLPVVSTMIGFCMLWIVGKWQAIRDGWLPCLLTGAVIGVVARF
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TNQYDNLVVLTGVLCGIAVIAAMAAYLVVTGGKVIDRSLLSAEEREFAAAMPLWRAFMPW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLVILILVLNVPQDLFSWLYRTMKLPIAGLTADGKPLDTRALWQAYTWILVSTILAVPF
HHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
LKPTGEQLRETVRTWVRRAPRPVFAAAVFFAIGEIMNMAGYDMAAGRFVVPSMVTVLADS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
SALAFQGMYGEVVAFIGLFGGFITGSEASTIAMFAKYTMTTAKNLDMPLSGLIIVTAGLA
CHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FGGGLASVISPAKLQNAAAAIDRIGEEGKVIRIAFVFALLLTLVTSLFVVVLLTVNGMGR
HCCCHHHHCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VS
CC
>Mature Secondary Structure
MLLEVIPLTLPLLLTLLPIVVILVMLLVFRKAADVSGIIGWLAISVVAWLGFQTAPEVIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RSTAAGFIRSFSVSLIVATSLLQMALMEKTGALRRITIFIRTIASDNRAVQIMMINIGFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECHH
TLMVAVGATPVSILPPILLAMGYSTYVAIALPAIGYDSLCTYALLGAPIVVFVDIANSFL
HHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHC
GKGNEIALHQAGMVFYMFLPVVSTMIGFCMLWIVGKWQAIRDGWLPCLLTGAVIGVVARF
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TNQYDNLVVLTGVLCGIAVIAAMAAYLVVTGGKVIDRSLLSAEEREFAAAMPLWRAFMPW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLVILILVLNVPQDLFSWLYRTMKLPIAGLTADGKPLDTRALWQAYTWILVSTILAVPF
HHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
LKPTGEQLRETVRTWVRRAPRPVFAAAVFFAIGEIMNMAGYDMAAGRFVVPSMVTVLADS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
SALAFQGMYGEVVAFIGLFGGFITGSEASTIAMFAKYTMTTAKNLDMPLSGLIIVTAGLA
CHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FGGGLASVISPAKLQNAAAAIDRIGEEGKVIRIAFVFALLLTLVTSLFVVVLLTVNGMGR
HCCCHHHHCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA