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The map label for this gene is ctaC [H]

Identifier: 39995332

GI number: 39995332

Start: 230508

End: 231374

Strand: Direct

Name: ctaC [H]

Synonym: GSU0222

Alternate gene names: 39995332

Gene position: 230508-231374 (Clockwise)

Preceding gene: 39995331

Following gene: 39995333

Centisome position: 6.04

GC content: 62.63

Gene sequence:

>867_bases
ATGTTCATCCTGGGGGCCTGCATCCTCCTCCTGACCGGCATCACGGTGGTCATGGTGGCCTTTGTCATCCGCTACCACCG
CTCCCGCTCCCCCGAGCCCACGTCGCAGGCGGCGACGAATCTCTGGCTGGAGATCGTCTGGACGGCCCTTCCCACGGTGC
TGGTTCTGGCCATGTTCTACTACGGCTGGTCCAGCTACCTGTCGCTTCGTCATGTGCCGCCGGGGGCCATGGAAGTTACG
GCCGTTGGCCGCATGTGGTCCTGGAGCTTCGAGTATCCGGGCGGCAGGACGAGCCCTCGTCTCTACGTGCCGGTGGGCAA
GCCGGTGCGGGTCGATCTGGTGTCCAAAGACGTTCTGCACGGGTTCTATATTCCCGCATTCCGGGTGAAGCGGGACGTGG
TGCCGGGGATGAAGAACCATGTCTGGTTCGTGGCTCCCAAGGCAGGTTCCTATGACATCTTCTGCTCGGTTTACTGCGGT
ACCGGTCACTCGGCCATGATCACTACAGTGGAGGCGATTCCCGACGCGGAGTTCCAGGCGTGGCTCAGCCATGGGGAGGA
AGGGGAAAAGGAGAAAGAAGGACACGGCAGAGAACTGCTGGAGAAGCACGGCTGCCTCGGCTGCCATTCCCTGGATGGGT
CTCCCCGGCTGGGCCCCACGTTTAAGGGTATCTGGGGCCACCAGGTGACCGTGACGGAGGATGGCGTCGAGCGGACCCTG
ACCGTGGACGAGGCATACCTCGTGCGTTCCATCCGTCAGCCGGCGGCCCAGGTTGTCAAGGGATTCCCGCCGGTCATGCC
GCCCTATCCGGGACTTAGCGATGAAGAGGTGGAGGAGATGGTGGAATTCATCAGGGAGCTCAAGTGA

Upstream 100 bases:

>100_bases
CCTGTTCATCGGAATCACCTTCTTCGACGTGCTCTACCGCTGAGGGACTGACGTGCGCGATTTCCCTACCACCACAACCG
AAGCCGTTGACCCGGTCTTC

Downstream 100 bases:

>100_bases
CCCGGCAGGACCTTGTTCTCTTCAGGCCCCGGCTGGCGCTGCTGAATGGCATCGCGGCGGTGGCGGGGCATGCCCTTGTC
CCCGATGCCGCACATGCGAC

Product: cytochrome C oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MFILGACILLLTGITVVMVAFVIRYHRSRSPEPTSQAATNLWLEIVWTALPTVLVLAMFYYGWSSYLSLRHVPPGAMEVT
AVGRMWSWSFEYPGGRTSPRLYVPVGKPVRVDLVSKDVLHGFYIPAFRVKRDVVPGMKNHVWFVAPKAGSYDIFCSVYCG
TGHSAMITTVEAIPDAEFQAWLSHGEEGEKEKEGHGRELLEKHGCLGCHSLDGSPRLGPTFKGIWGHQVTVTEDGVERTL
TVDEAYLVRSIRQPAAQVVKGFPPVMPPYPGLSDEEVEEMVEFIRELK

Sequences:

>Translated_288_residues
MFILGACILLLTGITVVMVAFVIRYHRSRSPEPTSQAATNLWLEIVWTALPTVLVLAMFYYGWSSYLSLRHVPPGAMEVT
AVGRMWSWSFEYPGGRTSPRLYVPVGKPVRVDLVSKDVLHGFYIPAFRVKRDVVPGMKNHVWFVAPKAGSYDIFCSVYCG
TGHSAMITTVEAIPDAEFQAWLSHGEEGEKEKEGHGRELLEKHGCLGCHSLDGSPRLGPTFKGIWGHQVTVTEDGVERTL
TVDEAYLVRSIRQPAAQVVKGFPPVMPPYPGLSDEEVEEMVEFIRELK
>Mature_288_residues
MFILGACILLLTGITVVMVAFVIRYHRSRSPEPTSQAATNLWLEIVWTALPTVLVLAMFYYGWSSYLSLRHVPPGAMEVT
AVGRMWSWSFEYPGGRTSPRLYVPVGKPVRVDLVSKDVLHGFYIPAFRVKRDVVPGMKNHVWFVAPKAGSYDIFCSVYCG
TGHSAMITTVEAIPDAEFQAWLSHGEEGEKEKEGHGRELLEKHGCLGCHSLDGSPRLGPTFKGIWGHQVTVTEDGVERTL
TVDEAYLVRSIRQPAAQVVKGFPPVMPPYPGLSDEEVEEMVEFIRELK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=160, Percent_Identity=27.5, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1786635, Length=195, Percent_Identity=24.6153846153846, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32123; Mature: 32123

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFILGACILLLTGITVVMVAFVIRYHRSRSPEPTSQAATNLWLEIVWTALPTVLVLAMFY
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGWSSYLSLRHVPPGAMEVTAVGRMWSWSFEYPGGRTSPRLYVPVGKPVRVDLVSKDVLH
HHHHHHEEEECCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCEEEEHHHHHHHH
GFYIPAFRVKRDVVPGMKNHVWFVAPKAGSYDIFCSVYCGTGHSAMITTVEAIPDAEFQA
HHCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEEHHHCCCHHHHH
WLSHGEEGEKEKEGHGRELLEKHGCLGCHSLDGSPRLGPTFKGIWGHQVTVTEDGVERTL
HHHCCCCCCHHHCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
TVDEAYLVRSIRQPAAQVVKGFPPVMPPYPGLSDEEVEEMVEFIRELK
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFILGACILLLTGITVVMVAFVIRYHRSRSPEPTSQAATNLWLEIVWTALPTVLVLAMFY
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGWSSYLSLRHVPPGAMEVTAVGRMWSWSFEYPGGRTSPRLYVPVGKPVRVDLVSKDVLH
HHHHHHEEEECCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCEEEEHHHHHHHH
GFYIPAFRVKRDVVPGMKNHVWFVAPKAGSYDIFCSVYCGTGHSAMITTVEAIPDAEFQA
HHCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEEHHHCCCHHHHH
WLSHGEEGEKEKEGHGRELLEKHGCLGCHSLDGSPRLGPTFKGIWGHQVTVTEDGVERTL
HHHCCCCCCHHHCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
TVDEAYLVRSIRQPAAQVVKGFPPVMPPYPGLSDEEVEEMVEFIRELK
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]