Click here to switch to the map view.

The map label for this gene is ykpA [H]

Identifier: 39995280

GI number: 39995280

Start: 185171

End: 186808

Strand: Direct

Name: ykpA [H]

Synonym: GSU0169

Alternate gene names: 39995280

Gene position: 185171-186808 (Clockwise)

Preceding gene: 39995279

Following gene: 39995281

Centisome position: 4.85

GC content: 62.7

Gene sequence:

>1638_bases
ATGATCAGTACCAGCAACATCAGCTTGGCCTATGGCAAGCGGGTCATCTTCAAGGACGTGAACATCAAGTTCGTGCCCGG
CAACTGCTACGGCCTGATCGGCGCCAACGGCGCCGGCAAGTCCACCTTCCTCAAGATTCTGGCGGGTCTGTCCGAGCCCG
ATTCCGGCACGGTCAGCGTCGGCCCGCGCGAGCGGATTTCATTCCTGAAGCAGGATCAGTTCGCCTTTGACGAGCACACG
GTCTTCAATACCGTTATCATGGGCAATCCCCGGCTGTACGAGGTGATGCACGAGCGTGAGGCGATCTACGCCAAGGCGGA
ATTCTCCGAGGAGGACGGCATCCGCTCCGCCGAGCTGGAGGCTGAGTTTGCCGAGATGGACGGCTACGAGGCGGAGTCCG
AGGCGGCGGTGCTGCTGAACGGCCTGGGGATTCCGGAAGAGCTGCGCCACAAGCAGATGAAGGAGCTGGAGGGGGGCGAG
AAGGTGCGGGTGCTGCTGGCCCAGGCGCTGTTCGGCAACCCGGATGTGCTGCTGTTGGACGAGCCCACCAACCACCTGGA
CCTGAAGACCATCACCTGGCTGGAGGATTTCCTGGCCCGGTTCAATAACACGGTGATCGTGGTATCCCACGACCGGCACT
TTCTCAACCAGATCTGCACCCACGTGGCGGACATCGACTTCGGCCGCATCCAGGTCTACGTGGGCAACTACGATTTCTGG
TACCAGGCCAGCCAGCTGACCCTGAAGCAGAAGCAGGACGAGAGCCGGAAGATCGCCGACAAGGCGGCCGAGCTGAAGGA
GTTCATCCAGCGCTTCAGCTCCAACGCCTCCAAGGCCAAGCAGGCCACCTCCCGCAAGAAGCTGCTGGAGAAGCTGACCG
TGGAGGAGATGCCGGTGTCGTCCCGCAAGTACCCCTACGTGGTCTTCAAGCCCGAGCGCCCCTGTGGCGACGTCATCCTG
GAGATCAGCGGCCTCTCCAAGGAGATCGACGGGGTTCAAGTGTTCAAGGACCTGGACCTGATCGTGGGGAAAGGGGACAA
GATCGCCTTTGTGGGCGCCAACAGCCTGGCCAAGACCACCCTGTTCCAGATCCTGGCCGGCGAGCTGGAGCCTGACGCGG
GTTCGTTCCGCTGGGGGGTGACCATCACCAGCGCCTACTTCCCCAAGGAGAACGGCAGCTATTTCGACAACGACCTGAAC
CTGATCGAGTGGCTGGGGCAGTTTGCTCCGCCGACGGAAGGGGAGAGCTTTGCCCGGGGCTTTCTCGGTAGGATGCTCTT
CTCCGGCGACGAGGCCACCAAGAAGGCCTCGGTCCTTTCCGGCGGCGAGCGGGTCCGCTGCATGCTGGCGCGGATGATGC
TGCTGGGCGCCAATGCCCTGGTGCTGGACGAGCCGACCAACCACCTGGACCTGGAGTCCATCACCGCCCTGAACAACGGC
CTGATCGCCTTCAGCGAGGTGGTGCTCTTCAGCTCCCACGACCACGAGTTCGTCAACACCCTGGCCAACCGGATCGTGGA
GTTCACCCCCGGTGGGATCATTGACCGGAAGATGACCTTCGACGACTACCTGGAGAGCGCCGAGGTGGCCGAAGAACGGG
ACCGGCTCTGCCAGGGGCACTGCGACCTGACGCTCTAG

Upstream 100 bases:

>100_bases
ATTGCCCGGCCAAGGCATAGTATGCTATAGCTAAAGTGCACCTGAACCGCAGGGAGACCCCCTGCGGTTTTCTTTTGGCA
GCAGAAAGAGAGAGTTCATC

Downstream 100 bases:

>100_bases
GAGCCTGTCGGGGTATCTCTTCCGCGAATATGACCAAACAGCACCTCGTTGCCACTATTATTGCCCGGCTTGAGGCCGAT
CTTGCCCTGTTCACCGCGGC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MISTSNISLAYGKRVIFKDVNIKFVPGNCYGLIGANGAGKSTFLKILAGLSEPDSGTVSVGPRERISFLKQDQFAFDEHT
VFNTVIMGNPRLYEVMHEREAIYAKAEFSEEDGIRSAELEAEFAEMDGYEAESEAAVLLNGLGIPEELRHKQMKELEGGE
KVRVLLAQALFGNPDVLLLDEPTNHLDLKTITWLEDFLARFNNTVIVVSHDRHFLNQICTHVADIDFGRIQVYVGNYDFW
YQASQLTLKQKQDESRKIADKAAELKEFIQRFSSNASKAKQATSRKKLLEKLTVEEMPVSSRKYPYVVFKPERPCGDVIL
EISGLSKEIDGVQVFKDLDLIVGKGDKIAFVGANSLAKTTLFQILAGELEPDAGSFRWGVTITSAYFPKENGSYFDNDLN
LIEWLGQFAPPTEGESFARGFLGRMLFSGDEATKKASVLSGGERVRCMLARMMLLGANALVLDEPTNHLDLESITALNNG
LIAFSEVVLFSSHDHEFVNTLANRIVEFTPGGIIDRKMTFDDYLESAEVAEERDRLCQGHCDLTL

Sequences:

>Translated_545_residues
MISTSNISLAYGKRVIFKDVNIKFVPGNCYGLIGANGAGKSTFLKILAGLSEPDSGTVSVGPRERISFLKQDQFAFDEHT
VFNTVIMGNPRLYEVMHEREAIYAKAEFSEEDGIRSAELEAEFAEMDGYEAESEAAVLLNGLGIPEELRHKQMKELEGGE
KVRVLLAQALFGNPDVLLLDEPTNHLDLKTITWLEDFLARFNNTVIVVSHDRHFLNQICTHVADIDFGRIQVYVGNYDFW
YQASQLTLKQKQDESRKIADKAAELKEFIQRFSSNASKAKQATSRKKLLEKLTVEEMPVSSRKYPYVVFKPERPCGDVIL
EISGLSKEIDGVQVFKDLDLIVGKGDKIAFVGANSLAKTTLFQILAGELEPDAGSFRWGVTITSAYFPKENGSYFDNDLN
LIEWLGQFAPPTEGESFARGFLGRMLFSGDEATKKASVLSGGERVRCMLARMMLLGANALVLDEPTNHLDLESITALNNG
LIAFSEVVLFSSHDHEFVNTLANRIVEFTPGGIIDRKMTFDDYLESAEVAEERDRLCQGHCDLTL
>Mature_545_residues
MISTSNISLAYGKRVIFKDVNIKFVPGNCYGLIGANGAGKSTFLKILAGLSEPDSGTVSVGPRERISFLKQDQFAFDEHT
VFNTVIMGNPRLYEVMHEREAIYAKAEFSEEDGIRSAELEAEFAEMDGYEAESEAAVLLNGLGIPEELRHKQMKELEGGE
KVRVLLAQALFGNPDVLLLDEPTNHLDLKTITWLEDFLARFNNTVIVVSHDRHFLNQICTHVADIDFGRIQVYVGNYDFW
YQASQLTLKQKQDESRKIADKAAELKEFIQRFSSNASKAKQATSRKKLLEKLTVEEMPVSSRKYPYVVFKPERPCGDVIL
EISGLSKEIDGVQVFKDLDLIVGKGDKIAFVGANSLAKTTLFQILAGELEPDAGSFRWGVTITSAYFPKENGSYFDNDLN
LIEWLGQFAPPTEGESFARGFLGRMLFSGDEATKKASVLSGGERVRCMLARMMLLGANALVLDEPTNHLDLESITALNNG
LIAFSEVVLFSSHDHEFVNTLANRIVEFTPGGIIDRKMTFDDYLESAEVAEERDRLCQGHCDLTL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=32.0224719101124, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI10947137, Length=562, Percent_Identity=30.6049822064057, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI27881506, Length=547, Percent_Identity=30.5301645338208, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI10947135, Length=503, Percent_Identity=29.8210735586481, Blast_Score=189, Evalue=9e-48,
Organism=Homo sapiens, GI69354671, Length=503, Percent_Identity=29.8210735586481, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI9961252, Length=218, Percent_Identity=25.2293577981651, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4505771, Length=218, Percent_Identity=25.2293577981651, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI9961250, Length=218, Percent_Identity=25.2293577981651, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI255708477, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI42741659, Length=246, Percent_Identity=28.4552845528455, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI73747915, Length=216, Percent_Identity=28.2407407407407, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21536376, Length=236, Percent_Identity=24.1525423728814, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=48.0075901328273, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1789751, Length=531, Percent_Identity=32.7683615819209, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI2367384, Length=511, Percent_Identity=31.1154598825832, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI1787182, Length=535, Percent_Identity=30.2803738317757, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1788165, Length=219, Percent_Identity=28.7671232876712, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788225, Length=255, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786703, Length=207, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=234, Percent_Identity=28.2051282051282, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994883, Length=250, Percent_Identity=25.6, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789864, Length=232, Percent_Identity=24.5689655172414, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786319, Length=227, Percent_Identity=25.5506607929515, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788506, Length=230, Percent_Identity=23.4782608695652, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081709, Length=247, Percent_Identity=24.2914979757085, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789593, Length=233, Percent_Identity=26.1802575107296, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=216, Percent_Identity=25, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=225, Percent_Identity=28.8888888888889, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787105, Length=220, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=532, Percent_Identity=31.9548872180451, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17555318, Length=514, Percent_Identity=28.988326848249, Blast_Score=231, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17559834, Length=551, Percent_Identity=27.7676950998185, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17558664, Length=221, Percent_Identity=28.5067873303167, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17541710, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320874, Length=516, Percent_Identity=31.7829457364341, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=31.6546762589928, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6325030, Length=377, Percent_Identity=25.9946949602122, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=407, Percent_Identity=24.8157248157248, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323278, Length=407, Percent_Identity=23.0958230958231, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=31.8867924528302, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24642252, Length=550, Percent_Identity=29.4545454545455, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI18859989, Length=550, Percent_Identity=29.4545454545455, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=29.5748613678373, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI21357907, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136662, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60763; Mature: 60763

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTSNISLAYGKRVIFKDVNIKFVPGNCYGLIGANGAGKSTFLKILAGLSEPDSGTVSV
CCCCCCEEHCCCCEEEEEECEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEC
GPRERISFLKQDQFAFDEHTVFNTVIMGNPRLYEVMHEREAIYAKAEFSEEDGIRSAELE
CHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEEEECCCCCCCCCCHHHH
AEFAEMDGYEAESEAAVLLNGLGIPEELRHKQMKELEGGEKVRVLLAQALFGNPDVLLLD
HHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDLKTITWLEDFLARFNNTVIVVSHDRHFLNQICTHVADIDFGRIQVYVGNYDFW
CCCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YQASQLTLKQKQDESRKIADKAAELKEFIQRFSSNASKAKQATSRKKLLEKLTVEEMPVS
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SRKYPYVVFKPERPCGDVILEISGLSKEIDGVQVFKDLDLIVGKGDKIAFVGANSLAKTT
CCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEEEECCHHHHHH
LFQILAGELEPDAGSFRWGVTITSAYFPKENGSYFDNDLNLIEWLGQFAPPTEGESFARG
HHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
FLGRMLFSGDEATKKASVLSGGERVRCMLARMMLLGANALVLDEPTNHLDLESITALNNG
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCC
LIAFSEVVLFSSHDHEFVNTLANRIVEFTPGGIIDRKMTFDDYLESAEVAEERDRLCQGH
CCEEEHEEEECCCCHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCC
CDLTL
CCCCC
>Mature Secondary Structure
MISTSNISLAYGKRVIFKDVNIKFVPGNCYGLIGANGAGKSTFLKILAGLSEPDSGTVSV
CCCCCCEEHCCCCEEEEEECEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEC
GPRERISFLKQDQFAFDEHTVFNTVIMGNPRLYEVMHEREAIYAKAEFSEEDGIRSAELE
CHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEEEECCCCCCCCCCHHHH
AEFAEMDGYEAESEAAVLLNGLGIPEELRHKQMKELEGGEKVRVLLAQALFGNPDVLLLD
HHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDLKTITWLEDFLARFNNTVIVVSHDRHFLNQICTHVADIDFGRIQVYVGNYDFW
CCCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YQASQLTLKQKQDESRKIADKAAELKEFIQRFSSNASKAKQATSRKKLLEKLTVEEMPVS
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SRKYPYVVFKPERPCGDVILEISGLSKEIDGVQVFKDLDLIVGKGDKIAFVGANSLAKTT
CCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEECCCCEEEEEECCHHHHHH
LFQILAGELEPDAGSFRWGVTITSAYFPKENGSYFDNDLNLIEWLGQFAPPTEGESFARG
HHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
FLGRMLFSGDEATKKASVLSGGERVRCMLARMMLLGANALVLDEPTNHLDLESITALNNG
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCC
LIAFSEVVLFSSHDHEFVNTLANRIVEFTPGGIIDRKMTFDDYLESAEVAEERDRLCQGH
CCEEEHEEEECCCCHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCC
CDLTL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]