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The map label for this gene is yfbQ [C]

Identifier: 39995228

GI number: 39995228

Start: 131671

End: 132975

Strand: Reverse

Name: yfbQ [C]

Synonym: GSU0117

Alternate gene names: 39995228

Gene position: 132975-131671 (Counterclockwise)

Preceding gene: 39995229

Following gene: 39995216

Centisome position: 3.49

GC content: 57.47

Gene sequence:

>1305_bases
GTGAGAAATGAACTGGTTACGCCAGGAGCCGGCGAACTGACCTATGAAATCCGCAACATCGTGAATGTGGCGGAAAAGCT
CCAGAAGCACGGCGTCAAGATCAACTGGGAGAATATCGGCGATCCGATCGTGAAGAAGGAGGAAATCCCCCGCTGGATGA
AGGAAATCGTGGCAGCCGCCGTGATGGAGAACGATACCTGGGGCTACTGCCATACCCGTGGGGTACTGGAAACCCGGGAG
TTTCTCTGCGGGCTGACCAACAACCGCGGCGGGGCCCAGATCACCCCCGACGACATCATCTTCTTCAACGGACTTGGCGA
TGCCATCTCCACGGTTTATGGCAATCTTCGCCACGAAAGCCGTATTCTGATGCCATCCCCCACCTATACCACCCACTCCA
TCGGGGAAGCCGCCCACGCCCAGGCAGCGCCGGTCTGCTACAGGCTGAAGCCCGAAGACAACTGGTTCCCCGACGTGGAA
GATCTGGAGAACCATGTAAAATATAATCCGCAGATCTCCGGCATCCTTCTCATTAATCCGGACAATCCCACCGGCATGGT
CTACCCCAGGGAGATCCTCGAACAGATCGTAGCCATCGCCCGCAGGTACGATCTCTTCATCATTGCCGACGAGGTCTACA
ACAACATCACGTACAACGGCCAGACCACCGTGCCCATCTCCGACGTGATCGGCGAGGTGCCGGCCATTGCCATGAAGGGA
ATTTCAAAGGAAATCCCCTGGCCCGGCTCGCGCTGCGGCTGGATCGAGGTCTATAACGGCAACCGCGACGAGCAGTTCCA
CAAGTTCCTGAACTCCATCCTCACCGCCAAGATGAACGAAGTCTGCTCCACCACCCTGCCGCAGAAGTGCATCCCGGCCA
TCATGAAGCATCCCGAGTACCAGACGTACCTTCGGGAGCGAATCGCATGCTACGAGCGGATGAGCACCATCACCTACGAC
TGCCTCAAGCAGGTTCCGGGTCTCATGGTTAACCGGACCAACGGTGCCTTCTACATGTCGGTCGCGTTCCGGGACGGACT
CCTCACCGACCGGCAGTCGCTGCCCATCGAGAGCGTGGAGGTCCGTGAACTGGTGGAGAAGCTCGTGAACGCCCCCGGGG
TTTCGCCGGACAAACGTTTCGTCTATTATATCCTGGCAAGCACTGGCATCTGCATCGTACCTCTTTCTTCCTTCAACACC
CCGCTTCAGGGCTTCCGGGTTACGCTGCTTGAAAAGGATGAGAACGAGTGCATGCGCATTTACCGTACCCTGGCGGAGAG
GATCAAGGAGTACTTGAACTCCTGA

Upstream 100 bases:

>100_bases
GGAGGCGTATACGCTTCGTGTATCGGAAGGCCGTGGGTGACCCCCACGGCCTTTTTCATTTTCAGGCAACCACAACAGGA
CTACAAGGGGGACGACTGAC

Downstream 100 bases:

>100_bases
TCACGATTCGCCGTGGTAACATCAAAAGGGGTGACCGGAACAATCGGTCACCCCTTTTTTTCTTCTCTCCGATTGCCGCA
CCAACGGACAGCAGTCCGAG

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKKEEIPRWMKEIVAAAVMENDTWGYCHTRGVLETRE
FLCGLTNNRGGAQITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQAAPVCYRLKPEDNWFPDVE
DLENHVKYNPQISGILLINPDNPTGMVYPREILEQIVAIARRYDLFIIADEVYNNITYNGQTTVPISDVIGEVPAIAMKG
ISKEIPWPGSRCGWIEVYNGNRDEQFHKFLNSILTAKMNEVCSTTLPQKCIPAIMKHPEYQTYLRERIACYERMSTITYD
CLKQVPGLMVNRTNGAFYMSVAFRDGLLTDRQSLPIESVEVRELVEKLVNAPGVSPDKRFVYYILASTGICIVPLSSFNT
PLQGFRVTLLEKDENECMRIYRTLAERIKEYLNS

Sequences:

>Translated_434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKKEEIPRWMKEIVAAAVMENDTWGYCHTRGVLETRE
FLCGLTNNRGGAQITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQAAPVCYRLKPEDNWFPDVE
DLENHVKYNPQISGILLINPDNPTGMVYPREILEQIVAIARRYDLFIIADEVYNNITYNGQTTVPISDVIGEVPAIAMKG
ISKEIPWPGSRCGWIEVYNGNRDEQFHKFLNSILTAKMNEVCSTTLPQKCIPAIMKHPEYQTYLRERIACYERMSTITYD
CLKQVPGLMVNRTNGAFYMSVAFRDGLLTDRQSLPIESVEVRELVEKLVNAPGVSPDKRFVYYILASTGICIVPLSSFNT
PLQGFRVTLLEKDENECMRIYRTLAERIKEYLNS
>Mature_434_residues
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKKEEIPRWMKEIVAAAVMENDTWGYCHTRGVLETRE
FLCGLTNNRGGAQITPDDIIFFNGLGDAISTVYGNLRHESRILMPSPTYTTHSIGEAAHAQAAPVCYRLKPEDNWFPDVE
DLENHVKYNPQISGILLINPDNPTGMVYPREILEQIVAIARRYDLFIIADEVYNNITYNGQTTVPISDVIGEVPAIAMKG
ISKEIPWPGSRCGWIEVYNGNRDEQFHKFLNSILTAKMNEVCSTTLPQKCIPAIMKHPEYQTYLRERIACYERMSTITYD
CLKQVPGLMVNRTNGAFYMSVAFRDGLLTDRQSLPIESVEVRELVEKLVNAPGVSPDKRFVYYILASTGICIVPLSSFNT
PLQGFRVTLLEKDENECMRIYRTLAERIKEYLNS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=397, Percent_Identity=26.448362720403, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI215599424, Length=396, Percent_Identity=26.2626262626263, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507369, Length=313, Percent_Identity=24.9201277955272, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4885351, Length=376, Percent_Identity=26.5957446808511, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788627, Length=329, Percent_Identity=28.2674772036474, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788722, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=312, Percent_Identity=30.4487179487179, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=396, Percent_Identity=25.7575757575758, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320317, Length=374, Percent_Identity=27.0053475935829, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323118, Length=375, Percent_Identity=24.5333333333333, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=339, Percent_Identity=27.4336283185841, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI45551451, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641770, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641760, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641768, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641766, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641764, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49264; Mature: 49264

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKKEEIPRWMKEIVAAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VMENDTWGYCHTRGVLETREFLCGLTNNRGGAQITPDDIIFFNGLGDAISTVYGNLRHES
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCC
RILMPSPTYTTHSIGEAAHAQAAPVCYRLKPEDNWFPDVEDLENHVKYNPQISGILLINP
EEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEECC
DNPTGMVYPREILEQIVAIARRYDLFIIADEVYNNITYNGQTTVPISDVIGEVPAIAMKG
CCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHCCEEECCEECCCHHHHHCCHHHHHHHC
ISKEIPWPGSRCGWIEVYNGNRDEQFHKFLNSILTAKMNEVCSTTLPQKCIPAIMKHPEY
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
QTYLRERIACYERMSTITYDCLKQVPGLMVNRTNGAFYMSVAFRDGLLTDRQSLPIESVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHH
VRELVEKLVNAPGVSPDKRFVYYILASTGICIVPLSSFNTPLQGFRVTLLEKDENECMRI
HHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHH
YRTLAERIKEYLNS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRNELVTPGAGELTYEIRNIVNVAEKLQKHGVKINWENIGDPIVKKEEIPRWMKEIVAAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VMENDTWGYCHTRGVLETREFLCGLTNNRGGAQITPDDIIFFNGLGDAISTVYGNLRHES
HHCCCCCCEEECCCHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCC
RILMPSPTYTTHSIGEAAHAQAAPVCYRLKPEDNWFPDVEDLENHVKYNPQISGILLINP
EEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEECC
DNPTGMVYPREILEQIVAIARRYDLFIIADEVYNNITYNGQTTVPISDVIGEVPAIAMKG
CCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHCCEEECCEECCCHHHHHCCHHHHHHHC
ISKEIPWPGSRCGWIEVYNGNRDEQFHKFLNSILTAKMNEVCSTTLPQKCIPAIMKHPEY
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
QTYLRERIACYERMSTITYDCLKQVPGLMVNRTNGAFYMSVAFRDGLLTDRQSLPIESVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHH
VRELVEKLVNAPGVSPDKRFVYYILASTGICIVPLSSFNTPLQGFRVTLLEKDENECMRI
HHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHH
YRTLAERIKEYLNS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]