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The map label for this gene is atpH

Identifier: 39995221

GI number: 39995221

Start: 124600

End: 125142

Strand: Direct

Name: atpH

Synonym: GSU0110

Alternate gene names: 39995221

Gene position: 124600-125142 (Clockwise)

Preceding gene: 308513278

Following gene: 39995222

Centisome position: 3.27

GC content: 58.38

Gene sequence:

>543_bases
TTGATCTCGAACGCTATTGCACGTCGCTACGCCAAGGCGCTGGTGCAGCTCGGGGCCGAGGAGGGAGCGGTCGACCGGTT
CGGTGTCGAGTTGGGGCAGTTCACGGCCCTTCTCGACGGGAATGCCGACCTGGCTTCCGTTCTCAAGAGCCCCGCGTACC
GCATTGAAGCCAAGAGGGAAATTCTCAGGGATGTCCTTGCGAAGCTTAATCTCTCCGGCACCGTCTCCAATTTTCTGCAG
GTACTCCTCGATAGGGGGCGAATCGGCTTCACTCCCCAGATCGCGCACAGCTACGCAGTATTTGCCGATGAACTCTCCGG
CATTGTCCGCCCGGTCCTCACGTCGGCATTTCCTTTGGACGATGCCCAGGTTGAGGGGATGAAGAGTGCCCTTGCCAAAG
CGACCGGCAAGCGGGTAGAGCTTTCGGCTCAAGTGGACTCCGCTCTCATCGGCGGAGTGGTCACCAAGATTGGCGACAAG
GTATTTGACGGCAGCGTACGGACCCAGTTGAACAGGATTCAGGATATATTACAGAAGGGGTGA

Upstream 100 bases:

>100_bases
TCGCGGTACAGATGGCCGAGCAGGCTCTGCGCGAGGCTATCAAGAAAGATGACCAGGATCGGCTGGTTAGCGAATATCTT
ACCAAGGTGGAGAACTTACA

Downstream 100 bases:

>100_bases
GAGGTTCCATGGAAATCAGAGCCGAAGAAATCAGCGAAATTATCCGTAAGCAGATCAAGGAGTACGGCAAGGAGGTAGAG
GTTGCCGAGACCGGCACCAT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKREILRDVLAKLNLSGTVSNFLQ
VLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLDDAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDK
VFDGSVRTQLNRIQDILQKG

Sequences:

>Translated_180_residues
MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKREILRDVLAKLNLSGTVSNFLQ
VLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLDDAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDK
VFDGSVRTQLNRIQDILQKG
>Mature_180_residues
MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKREILRDVLAKLNLSGTVSNFLQ
VLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLDDAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDK
VFDGSVRTQLNRIQDILQKG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=167, Percent_Identity=28.1437125748503, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1790173, Length=173, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71984710, Length=171, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=24.5614035087719, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320504, Length=174, Percent_Identity=28.1609195402299, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647054, Length=172, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_GEOSL (Q74GY3)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951172.1
- ProteinModelPortal:   Q74GY3
- SMR:   Q74GY3
- GeneID:   2688080
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0110
- NMPDR:   fig|243231.1.peg.110
- TIGR:   GSU0110
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- ProtClustDB:   PRK13429
- BioCyc:   GSUL243231:GSU_0110-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19268; Mature: 19268

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKRE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
ILRDVLAKLNLSGTVSNFLQVLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLD
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDKVFDGSVRTQLNRIQDILQKG
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKRE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
ILRDVLAKLNLSGTVSNFLQVLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLD
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDKVFDGSVRTQLNRIQDILQKG
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA