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The map label for this gene is icfA [H]

Identifier: 39995178

GI number: 39995178

Start: 83254

End: 83901

Strand: Direct

Name: icfA [H]

Synonym: GSU0067

Alternate gene names: 39995178

Gene position: 83254-83901 (Clockwise)

Preceding gene: 39995177

Following gene: 39995179

Centisome position: 2.18

GC content: 57.87

Gene sequence:

>648_bases
ATGATAACCAGGCTTCTTGAGGGGAACCGGCGTTTTGTGGCGGAGGTCTTTGAAAAGGAGCGCGAGACCTTTGCGACCCT
TGCCCGGGGGCAGCGTCCGACAGTTCTCTGGATCGGTTGCTCCGACTCTCGAGTGCCGGTCAACACCATTACCCAGACCA
AGGCGGGAGAAGTTTTCGTCCACCGTAACGTGGGGAACGTGGTCTCGGTCAACGACTGGAACCTTTCGGCAGTGCTCGAA
TTCTCGATCAACCATTTGTGCATCCCCGATATCGTTATCTGTGGTCACTACGGCTGCGGCGGCATTCAGGCCCTGGACGA
GGAGCGGGCTGACGACAAATACATTCCCATCTGGCTCATCAATGCCTACAAGGCCAAGGAACGGGTCGACGAAAAGATCC
GGGCGCTCCACATCGGTCTCCCTCCCGAGCAGCGTATGAAGCTCATCGTGGAGGAAAATGTCCGGCTCCAGCTGGAACAC
CTGCGCGAATATCCCTTTGTCCGTACCGCCATGCGCCAAGGCAAACTGAGCATCCATGGCTGGATTTACGACATGGAGAG
CGGTGAAATCAAGATTCTGTCCACTGAGCGGCCAGGAGAGGGGGCGGCAGTTTCGTCCCGGGCCACGGAGTATTGCCCGC
TCCCGTAA

Upstream 100 bases:

>100_bases
ACCATCCGGTATTCATTCGTGGATGCCGATTACACCCGGCGCCTCGAGCCGGCGACGATACTAGACGTGTTGGAGCGGAT
CCGCGAGGAGAGGGGGCGTG

Downstream 100 bases:

>100_bases
GTTTCGTCGCAAAGGGGCCTTGCTGTTCCCTCTAAGCAAACGCTGCCCCGGATCCCGGCTCTGCATCGCCGGAAGAATTG
TAGAATGGTTGAAGAGGAGG

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MITRLLEGNRRFVAEVFEKERETFATLARGQRPTVLWIGCSDSRVPVNTITQTKAGEVFVHRNVGNVVSVNDWNLSAVLE
FSINHLCIPDIVICGHYGCGGIQALDEERADDKYIPIWLINAYKAKERVDEKIRALHIGLPPEQRMKLIVEENVRLQLEH
LREYPFVRTAMRQGKLSIHGWIYDMESGEIKILSTERPGEGAAVSSRATEYCPLP

Sequences:

>Translated_215_residues
MITRLLEGNRRFVAEVFEKERETFATLARGQRPTVLWIGCSDSRVPVNTITQTKAGEVFVHRNVGNVVSVNDWNLSAVLE
FSINHLCIPDIVICGHYGCGGIQALDEERADDKYIPIWLINAYKAKERVDEKIRALHIGLPPEQRMKLIVEENVRLQLEH
LREYPFVRTAMRQGKLSIHGWIYDMESGEIKILSTERPGEGAAVSSRATEYCPLP
>Mature_215_residues
MITRLLEGNRRFVAEVFEKERETFATLARGQRPTVLWIGCSDSRVPVNTITQTKAGEVFVHRNVGNVVSVNDWNLSAVLE
FSINHLCIPDIVICGHYGCGGIQALDEERADDKYIPIWLINAYKAKERVDEKIRALHIGLPPEQRMKLIVEENVRLQLEH
LREYPFVRTAMRQGKLSIHGWIYDMESGEIKILSTERPGEGAAVSSRATEYCPLP

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=194, Percent_Identity=37.1134020618557, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786318, Length=198, Percent_Identity=35.8585858585859, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25147564, Length=237, Percent_Identity=25.7383966244726, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324292, Length=174, Percent_Identity=35.0574712643678, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24443; Mature: 24443

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRLLEGNRRFVAEVFEKERETFATLARGQRPTVLWIGCSDSRVPVNTITQTKAGEVFV
CCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHCCCCCCCEEEE
HRNVGNVVSVNDWNLSAVLEFSINHLCIPDIVICGHYGCGGIQALDEERADDKYIPIWLI
EECCCCEEEECCCCEEEEEEECCCCEECCCEEEECCCCCCCCCHHHHHCCCCCEEEEEEE
NAYKAKERVDEKIRALHIGLPPEQRMKLIVEENVRLQLEHLREYPFVRTAMRQGKLSIHG
ECHHHHHHHHHHHHEEECCCCHHHHHEEEECCCCEEEHHHHHHCCHHHHHHHCCCEEEEE
WIYDMESGEIKILSTERPGEGAAVSSRATEYCPLP
EEEEECCCCEEEEECCCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MITRLLEGNRRFVAEVFEKERETFATLARGQRPTVLWIGCSDSRVPVNTITQTKAGEVFV
CCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHCCCCCCCEEEE
HRNVGNVVSVNDWNLSAVLEFSINHLCIPDIVICGHYGCGGIQALDEERADDKYIPIWLI
EECCCCEEEECCCCEEEEEEECCCCEECCCEEEECCCCCCCCCHHHHHCCCCCEEEEEEE
NAYKAKERVDEKIRALHIGLPPEQRMKLIVEENVRLQLEHLREYPFVRTAMRQGKLSIHG
ECHHHHHHHHHHHHEEECCCCHHHHHEEEECCCCEEEHHHHHHCCHHHHHHHCCCEEEEE
WIYDMESGEIKILSTERPGEGAAVSSRATEYCPLP
EEEEECCCCEEEEECCCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]