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The map label for this gene is mtnU [H]

Identifier: 39995140

GI number: 39995140

Start: 38522

End: 39301

Strand: Reverse

Name: mtnU [H]

Synonym: GSU0029

Alternate gene names: 39995140

Gene position: 39301-38522 (Counterclockwise)

Preceding gene: 39995146

Following gene: 39995139

Centisome position: 1.03

GC content: 62.95

Gene sequence:

>780_bases
ATGAATCGGACCGTCAAGGCAGGAGCCGTACAGTTCACTGTCAGGCTCGGCGATATTGACGCAAACGTGGCGTACGTCCA
GAAAGCCCTGCGGCGACTGGCATCCCAGGGATGCCGGCTGGCGGTTCTCCCCGAGATGTGGAGTACCGGCTACGCCTACA
AGGAGCTCAACGAACTGGCCAAGCGGACCCCTGAAGTGGTGGCGGAATTGGGCCGGCTCTCCAGGGAACTGGAGATGGTC
ATCGTCGGCAGCATGCCGGAGCCCCACGGTGAAAAGGTCTTCAATACCGCGTATGTTCTTGATCGTGGCGAGTTGCTCGG
TTCCTATCGCAAGATCCACCTCTTCTCCCTCATGGGAGAGGACCGCTCCCTAGACGGCGGCGACCGGTGGCTAGTGGTCG
ATACCCACGTGGGTCGGCTCGGCGTCTTCATCTGCTACGACCTTCGCTTCCCGGAGCTGGCGCGCCGGCTGGCGGTGGAA
GGAGCCGAAATCATCGTCGTCCCTGCCGAGTGGCCCAAACCGCGGGAAGAACACTGGCGGGCGCTGTTGCGGGCCCGGGC
CATCGAGAACCAGCTCTTCGTGGTGGCCGCCAACTGCTGCGGAGTCCAGGGCAAGCTCGACTTCTTCGGCTCCAGCCTGA
TCATCGACCCCAAGGGAGAGCTCCTGGCCGAAGGCGGCTACGACCCATGCGAACCAATGGCAACCCTCGACTTCCAGGTG
ATGGAGACATGGCGCGACCAGATACCCTGCTTCGCCGACCGCAGGCCTTCCTGCTACTGA

Upstream 100 bases:

>100_bases
CCGGCCGTCCACCATCTATTGAGTTGAAATATAAGCGGGTTGACGGTACACTCGTTCGTCATCCACAGGGTTTGTATCCC
CTGCACCCGGAGGCTTTCCC

Downstream 100 bases:

>100_bases
AACAGTTGACGGGCACAAGGACAAGGTCTAAGCTACCTTGTCGTTCCTATTTCATTATTCCGAGGGCGGACACCCTCAAC
CGGAGGTTGCATCGTGACAC

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNRTVKAGAVQFTVRLGDIDANVAYVQKALRRLASQGCRLAVLPEMWSTGYAYKELNELAKRTPEVVAELGRLSRELEMV
IVGSMPEPHGEKVFNTAYVLDRGELLGSYRKIHLFSLMGEDRSLDGGDRWLVVDTHVGRLGVFICYDLRFPELARRLAVE
GAEIIVVPAEWPKPREEHWRALLRARAIENQLFVVAANCCGVQGKLDFFGSSLIIDPKGELLAEGGYDPCEPMATLDFQV
METWRDQIPCFADRRPSCY

Sequences:

>Translated_259_residues
MNRTVKAGAVQFTVRLGDIDANVAYVQKALRRLASQGCRLAVLPEMWSTGYAYKELNELAKRTPEVVAELGRLSRELEMV
IVGSMPEPHGEKVFNTAYVLDRGELLGSYRKIHLFSLMGEDRSLDGGDRWLVVDTHVGRLGVFICYDLRFPELARRLAVE
GAEIIVVPAEWPKPREEHWRALLRARAIENQLFVVAANCCGVQGKLDFFGSSLIIDPKGELLAEGGYDPCEPMATLDFQV
METWRDQIPCFADRRPSCY
>Mature_259_residues
MNRTVKAGAVQFTVRLGDIDANVAYVQKALRRLASQGCRLAVLPEMWSTGYAYKELNELAKRTPEVVAELGRLSRELEMV
IVGSMPEPHGEKVFNTAYVLDRGELLGSYRKIHLFSLMGEDRSLDGGDRWLVVDTHVGRLGVFICYDLRFPELARRLAVE
GAEIIVVPAEWPKPREEHWRALLRARAIENQLFVVAANCCGVQGKLDFFGSSLIIDPKGELLAEGGYDPCEPMATLDFQV
METWRDQIPCFADRRPSCY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=250, Percent_Identity=32.8, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI297632348, Length=262, Percent_Identity=32.4427480916031, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI297632350, Length=262, Percent_Identity=32.4427480916031, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI5031947, Length=262, Percent_Identity=32.4427480916031, Blast_Score=111, Evalue=8e-25,
Organism=Escherichia coli, GI1786412, Length=239, Percent_Identity=30.1255230125523, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17556280, Length=262, Percent_Identity=31.6793893129771, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323383, Length=281, Percent_Identity=29.1814946619217, Blast_Score=136, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322335, Length=307, Percent_Identity=25.0814332247557, Blast_Score=95, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21355835, Length=255, Percent_Identity=30.1960784313725, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=32.2222222222222, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21358471, Length=256, Percent_Identity=27.34375, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29163; Mature: 29163

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTVKAGAVQFTVRLGDIDANVAYVQKALRRLASQGCRLAVLPEMWSTGYAYKELNELA
CCCCEECCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCHHHHHHHHH
KRTPEVVAELGRLSRELEMVIVGSMPEPHGEKVFNTAYVLDRGELLGSYRKIHLFSLMGE
HHCHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHEEEECHHHHHHHHHEEEEEEECC
DRSLDGGDRWLVVDTHVGRLGVFICYDLRFPELARRLAVEGAEIIVVPAEWPKPREEHWR
CCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
ALLRARAIENQLFVVAANCCGVQGKLDFFGSSLIIDPKGELLAEGGYDPCEPMATLDFQV
HHHHHHHHCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCEEECCCCCCCCCHHHHHHHH
METWRDQIPCFADRRPSCY
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNRTVKAGAVQFTVRLGDIDANVAYVQKALRRLASQGCRLAVLPEMWSTGYAYKELNELA
CCCCEECCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCHHHHHHHHH
KRTPEVVAELGRLSRELEMVIVGSMPEPHGEKVFNTAYVLDRGELLGSYRKIHLFSLMGE
HHCHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHEEEECHHHHHHHHHEEEEEEECC
DRSLDGGDRWLVVDTHVGRLGVFICYDLRFPELARRLAVEGAEIIVVPAEWPKPREEHWR
CCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
ALLRARAIENQLFVVAANCCGVQGKLDFFGSSLIIDPKGELLAEGGYDPCEPMATLDFQV
HHHHHHHHCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCEEECCCCCCCCCHHHHHHHH
METWRDQIPCFADRRPSCY
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]