Click here to switch to the map view.

The map label for this gene is higA [H]

Identifier: 39546386

GI number: 39546386

Start: 4239649

End: 4240077

Strand: Reverse

Name: higA [H]

Synonym: STM4030.S

Alternate gene names: 39546386

Gene position: 4240077-4239649 (Counterclockwise)

Preceding gene: 16767296

Following gene: 16767288

Centisome position: 87.29

GC content: 47.55

Gene sequence:

>429_bases
ATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCCACTGATGGGGGAAGACCG
AAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATCTTGAAAACCCACTATTTG
AATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAACCAACACCTGGAGAAAACG
CCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCTTGCCAACGAACTTGGTTC
TAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAGCGCTTACACAACGCTTCA
AACTACCAGCAGATGCCTTCATCGAGTAG

Upstream 100 bases:

>100_bases
GGTTACATAAGATATTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAA
GAATGAGAACTCATCGTCAG

Downstream 100 bases:

>100_bases
TTGGATATGTCCAGCTACTCCTCCTCATTCCCGCCCTCTTCATACGGGCCGAACGGTTTCGCAGGTAGTACGATATAAAT
GCCTTCGAAAATTGCTCCGG

Product: cytoplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MDATSAKKIVDTFSDAVKTVPLMGEDRNDNEYRRALALVEFLVDHDDLENPLFELLCARISEYEKHAPEFKALNQHLEKT
PPGVSVLRTLMDQYGLKAADLANELGSKSNVSNILNGRRALTVNHIKALTQRFKLPADAFIE

Sequences:

>Translated_142_residues
MDATSAKKIVDTFSDAVKTVPLMGEDRNDNEYRRALALVEFLVDHDDLENPLFELLCARISEYEKHAPEFKALNQHLEKT
PPGVSVLRTLMDQYGLKAADLANELGSKSNVSNILNGRRALTVNHIKALTQRFKLPADAFIE
>Mature_142_residues
MDATSAKKIVDTFSDAVKTVPLMGEDRNDNEYRRALALVEFLVDHDDLENPLFELLCARISEYEKHAPEFKALNQHLEKT
PPGVSVLRTLMDQYGLKAADLANELGSKSNVSNILNGRRALTVNHIKALTQRFKLPADAFIE

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin [H]

COG id: COG5499

COG function: function code K; Predicted transcription regulator containing HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789464, Length=122, Percent_Identity=45.9016393442623, Blast_Score=113, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 15924; Mature: 15924

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATSAKKIVDTFSDAVKTVPLMGEDRNDNEYRRALALVEFLVDHDDLENPLFELLCARI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SEYEKHAPEFKALNQHLEKTPPGVSVLRTLMDQYGLKAADLANELGSKSNVSNILNGRRA
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCHH
LTVNHIKALTQRFKLPADAFIE
HHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MDATSAKKIVDTFSDAVKTVPLMGEDRNDNEYRRALALVEFLVDHDDLENPLFELLCARI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SEYEKHAPEFKALNQHLEKTPPGVSVLRTLMDQYGLKAADLANELGSKSNVSNILNGRRA
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCHH
LTVNHIKALTQRFKLPADAFIE
HHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]