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The map label for this gene is higB [H]

Identifier: 16767296

GI number: 16767296

Start: 4240092

End: 4240403

Strand: Reverse

Name: higB [H]

Synonym: STM4031

Alternate gene names: 16767296

Gene position: 4240403-4240092 (Counterclockwise)

Preceding gene: 16767297

Following gene: 39546386

Centisome position: 87.3

GC content: 39.74

Gene sequence:

>312_bases
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Upstream 100 bases:

>100_bases
GGCAAAATGACCTAAAATTCAATTTTGTTTTCAACTTGAAAACTGGATAACGTTGCGCTAAATTGTTTTCAGGTTGAAAA
CTTTGTAATGGAACTACATT

Downstream 100 bases:

>100_bases
GAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCCACTG
ATGGGGGAAGACCGAAATGA

Product: cytoplasmic protein

Products: NA

Alternate protein names: Endoribonuclease HigB; Toxin HigB [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MHVISRKPFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRYIPSLDNFKYRDKWWVIDVSGNSLRLISYIDFRLHKI
FVKHIVSHAEYDKLTAYYRGNKE

Sequences:

>Translated_103_residues
MHVISRKPFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRYIPSLDNFKYRDKWWVIDVSGNSLRLISYIDFRLHKI
FVKHIVSHAEYDKLTAYYRGNKE
>Mature_103_residues
MHVISRKPFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRYIPSLDNFKYRDKWWVIDVSGNSLRLISYIDFRLHKI
FVKHIVSHAEYDKLTAYYRGNKE

Specific function: Part of a toxin-antitoxin (TA) module. A probable translation-dependent mRNA interferase [H]

COG id: COG4680

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HigB mRNA interferase family [H]

Homologues:

Organism=Escherichia coli, GI1789465, Length=99, Percent_Identity=41.4141414141414, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018669 [H]

Pfam domain/function: PF09907 DUF2136 [H]

EC number: NA

Molecular weight: Translated: 12465; Mature: 12465

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVISRKPFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRYIPSLDNFKYRDKWWVI
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEECCEEEEE
DVSGNSLRLISYIDFRLHKIFVKHIVSHAEYDKLTAYYRGNKE
EECCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCC
>Mature Secondary Structure
MHVISRKPFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRYIPSLDNFKYRDKWWVI
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEECCEEEEE
DVSGNSLRLISYIDFRLHKIFVKHIVSHAEYDKLTAYYRGNKE
EECCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]