Click here to switch to the map view.

The map label for this gene is ltrA [H]

Identifier: 38638062

GI number: 38638062

Start: 420589

End: 421515

Strand: Direct

Name: ltrA [H]

Synonym: PHG401

Alternate gene names: 38638062

Gene position: 420589-421515 (Clockwise)

Preceding gene: 38638052

Following gene: 38638067

Centisome position: 93.02

GC content: 57.39

Gene sequence:

>927_bases
ATGGAACTCGACGCTTACTTGTTTTTCGCCACGGTTGTGGAATCTGGCAGCTTCATGAATGCTTCGCTCAAGCTTGGCAT
TGACCGCTCCAATGTCAGCCGGCGCATCCGTAAGCTGGAGCGCGATGTGGAGGCGCAGCTCGTACGGCGGAGCACGCGCC
GCATGAGTCTGACGGAAATAGGCGAGGCGTTTTACGCGCAATGCGCCGTCATCCGCGCCGAGGTAGAGCGCGCGGACGAA
CTACTGCACACCTTCGGCACTTCCATCCGCGGTCCATTGCGTGTGAGTTGTCCACCGGCGGTCGGCCGACTGTACTTGAC
CGCTATGTTCGCCGAGTTCTGCAATCTGTATCCCAAGGTATCGCTGTCGGTGAGCTTCAAAGGCGGTGCCGTGGACCTGA
TGGAAAATGATCTCGACCTGGCTTTGCGGGTCACCAATGACCCCGGAGAACATTGTGTGGCGCGTGCCCTCGGGCCGATC
GAATGGATGCTATGCGCGAATCCCGAGTATTTGGAGCGGCATGGTCGACCGGTCACGCCGGAAGATTTGGCGTCTCATAC
CTGCCTTGGCGTGCGCACACGTGTGGGGCTGGAATATGTGCGAGAAGGCAGTGACCTCGTGCACAGGGTTTCCATCCAAC
CGCATTTGGAGTGCTCGGACTATGGTTTCCTTGGCGAAATGGCTGCGGCAAAGCTCGGCATTGGCTTGCTGCCTTCGTAT
GTCGCAGTAGAACATCTGCAAAGCGGTAGGCTGGAAACCGTCCTAAACGAATATAGGCTAACCCGTTCGCCTGGCAGCAC
ACTGTATGCGATCACGCTCCCTAACCGATACACGCCGCCGCAGTTGCGAGCATTTATTGACTTTCTGAAATCCAGATTCG
AGCAGGGCTTGCCTTGGGAGAAAGACTTGATGCGAACAGGCGCATAG

Upstream 100 bases:

>100_bases
AATCGGGCTTTGGGAGAGTATTGCATCCACTTTTCAGGCACGTAAGCCTGCGCTTGCGCACAGGTGCGTTGCGCGCAGCG
CACCAATCGCTGCTCAAACC

Downstream 100 bases:

>100_bases
CCCCCGCGAGTGCAAGGCCCAGCTGGCAGCTGCTATGCTTCGAGTCTGGGCAAAAAGGGGCAGCTGAAGCCTGAACAGCG
CGAAGCGTGCTCGTTCATCG

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MELDAYLFFATVVESGSFMNASLKLGIDRSNVSRRIRKLERDVEAQLVRRSTRRMSLTEIGEAFYAQCAVIRAEVERADE
LLHTFGTSIRGPLRVSCPPAVGRLYLTAMFAEFCNLYPKVSLSVSFKGGAVDLMENDLDLALRVTNDPGEHCVARALGPI
EWMLCANPEYLERHGRPVTPEDLASHTCLGVRTRVGLEYVREGSDLVHRVSIQPHLECSDYGFLGEMAAAKLGIGLLPSY
VAVEHLQSGRLETVLNEYRLTRSPGSTLYAITLPNRYTPPQLRAFIDFLKSRFEQGLPWEKDLMRTGA

Sequences:

>Translated_308_residues
MELDAYLFFATVVESGSFMNASLKLGIDRSNVSRRIRKLERDVEAQLVRRSTRRMSLTEIGEAFYAQCAVIRAEVERADE
LLHTFGTSIRGPLRVSCPPAVGRLYLTAMFAEFCNLYPKVSLSVSFKGGAVDLMENDLDLALRVTNDPGEHCVARALGPI
EWMLCANPEYLERHGRPVTPEDLASHTCLGVRTRVGLEYVREGSDLVHRVSIQPHLECSDYGFLGEMAAAKLGIGLLPSY
VAVEHLQSGRLETVLNEYRLTRSPGSTLYAITLPNRYTPPQLRAFIDFLKSRFEQGLPWEKDLMRTGA
>Mature_308_residues
MELDAYLFFATVVESGSFMNASLKLGIDRSNVSRRIRKLERDVEAQLVRRSTRRMSLTEIGEAFYAQCAVIRAEVERADE
LLHTFGTSIRGPLRVSCPPAVGRLYLTAMFAEFCNLYPKVSLSVSFKGGAVDLMENDLDLALRVTNDPGEHCVARALGPI
EWMLCANPEYLERHGRPVTPEDLASHTCLGVRTRVGLEYVREGSDLVHRVSIQPHLECSDYGFLGEMAAAKLGIGLLPSY
VAVEHLQSGRLETVLNEYRLTRSPGSTLYAITLPNRYTPPQLRAFIDFLKSRFEQGLPWEKDLMRTGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=271, Percent_Identity=31.3653136531365, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=29.8611111111111, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=27.6450511945392, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=31.4685314685315, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=26.9896193771626, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=26.7796610169492, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=25.7627118644068, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787589, Length=301, Percent_Identity=22.5913621262458, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789173, Length=266, Percent_Identity=25.9398496240602, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693105, Length=202, Percent_Identity=25.7425742574257, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34486; Mature: 34486

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELDAYLFFATVVESGSFMNASLKLGIDRSNVSRRIRKLERDVEAQLVRRSTRRMSLTEI
CCCHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEAFYAQCAVIRAEVERADELLHTFGTSIRGPLRVSCPPAVGRLYLTAMFAEFCNLYPKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCE
SLSVSFKGGAVDLMENDLDLALRVTNDPGEHCVARALGPIEWMLCANPEYLERHGRPVTP
EEEEEECCCEEEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCH
EDLASHTCLGVRTRVGLEYVREGSDLVHRVSIQPHLECSDYGFLGEMAAAKLGIGLLPSY
HHHHHCCHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
VAVEHLQSGRLETVLNEYRLTRSPGSTLYAITLPNRYTPPQLRAFIDFLKSRFEQGLPWE
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
KDLMRTGA
HHHHHCCC
>Mature Secondary Structure
MELDAYLFFATVVESGSFMNASLKLGIDRSNVSRRIRKLERDVEAQLVRRSTRRMSLTEI
CCCHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEAFYAQCAVIRAEVERADELLHTFGTSIRGPLRVSCPPAVGRLYLTAMFAEFCNLYPKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCE
SLSVSFKGGAVDLMENDLDLALRVTNDPGEHCVARALGPIEWMLCANPEYLERHGRPVTP
EEEEEECCCEEEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCH
EDLASHTCLGVRTRVGLEYVREGSDLVHRVSIQPHLECSDYGFLGEMAAAKLGIGLLPSY
HHHHHCCHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
VAVEHLQSGRLETVLNEYRLTRSPGSTLYAITLPNRYTPPQLRAFIDFLKSRFEQGLPWE
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
KDLMRTGA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]