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The map label for this gene is uvrD

Identifier: 38637982

GI number: 38637982

Start: 334913

End: 336373

Strand: Direct

Name: uvrD

Synonym: PHG321

Alternate gene names: NA

Gene position: 334913-336373 (Clockwise)

Preceding gene: 38637981

Following gene: 38637983

Centisome position: 74.07

GC content: 65.71

Gene sequence:

>1461_bases
ATGGTCCCCACCGACGAACAGGCTTCCGTTGTCGACGCGGTCAAGGCCGGCGGGCCGCTGAAAGTCAAGGCGTATGCGGG
CGCCGGCAAGACGTCGACGCTACGCCTGGCTGCCGAGGCCCGCGGCCGCGCGCGAGGGCTGTATCTGGCCTTCAACAAGG
ACATCGCCAACGAGGCTGCCCAGAAATTCCCGCAGAACACCCGCTGCCGTACCGTCCACTCGCTCGCGTACAGCGCCACG
CCGCCGGAACTCACCCGCAAGCTCAAGAACCCGGTCGAGCCGCCGCATCAGCTCGCTTTGCGCTACGGTCTCGCCAAGCT
GCGCCTGCCGACGACGATCGGCAAGGATCTCGAACTGAGCGCCAGCAAGGTCGCCCGAATAGTGATGGACGGCGCGGCGC
GTTTCTGCCGCTCCGCACAGGCCGAGCCTCTTGCGTGGCACATTCCAGTGGAGTCGATCGTGAAGGAGGAGGAGGCCGAG
CATCTGCGCGACTCGCTGCTGCCCTACGTCAAGCGGCTCTGGGGTGAATACCTCGACCCCGCTTCCCCGTCAGCGATCGT
TCACGACGTCTACGTAAAGAGGTGGGAGCGCAGCCGGCCGCGCATTGGTGCCGACTTCATCCTGTTCGACGAAGCGCAGG
ATGCCGATGGCCTGATGCTGTCGGTGCTGCGCGCGCAGCAGTCCCAGGTCATCTACGTCGGCGACCCGTACCAGCAGATC
TACGAATGGCGCGGCGCGGTCAACGCCATGGAGCATATTCGTGCACCTGAATGCGCTCTCACCGAATCGTTCCGTTTCGG
CCCGGCCATCGCTCAACTGGCCAGCCGCGTGCTGCGGCTCATGGACGAGGAAACGCCCGTCCGTGGACAGGACCACGTTG
AGTCCCGGATCCTGCACGACTCAACGCCAGGACAGGATCGCTTCGACGCCATCCTGTGCCGCAAGAACGCGACGGTCCTG
ACGCACCTTGCCCAGGGCATCGGCCGGGGCGATCGCGTGGCGGTGCGCGCCAACGTCGACGAGCTCCGCGCCTTTGCCGA
CGGCGCCGAGCAGCTCATGCGCGGCCAGCGCATCGGCTACCCCGCCACCCTCGCCCTGTTCGAAACGTGGGAAGAGGTCC
AGGAATATGCCGAATCGTTCGCCGGCCGCGACCTGAAGCCCCTCGTCACGTTGATCGACAACGAGGGCGTGGACTATCTG
CGCCTGATCCTCACCCGCGTCTCGCCAGAGGATGAGGCCGACTACATCGTGTCGACCGTCCACCGGGCCAAGGGCCTCGA
ATGGGAGCGCGTGCAGCTCGCCGGCGACTTCAAGTTCAAGACCGGCGACGACGGCGAACTCACCATGGCACCGGAAGAGA
TGCGCCTGCTTTACGTCGCCATGACACGCGCGAAGCGCCTGCTCGATGTGAGCGAGATCCGGCGCGACCTCTACACCATG
TTCCGGGAAGCCGGTGTCTAA

Upstream 100 bases:

>100_bases
AGTATGAGCGACGCTCGGAAGCCGCACGTGCAGACACACTGGCCATCCGCCGACGCGTTCTAGCCTCGCTGCCCGAGCAA
ACTGCATTGGAGATCGCCTG

Downstream 100 bases:

>100_bases
AGGAGAGACCATGATCACCGTGCGGATTGGCGGGAACGAGTACCCGCTGGATGAGGTTTTGGAAGATCCCGGCCGCTACG
CGCGCCACCTCGAGCGTGCC

Product: helicase superfamily protein I

Products: NA

Alternate protein names: Superfamily I DNA/RNA Helicase-Like Protein; Helicase; Superfamily I DNA/RNA Helicase; UvrD/REP Helicase; Superfamily I DNA And RNA Helicase; Helicase Superfamily Protein I; F-Box Only Protein; I DNA And RNA Helicase Protein; I DNA And RNA Helicase; UvrD/Rep Family Helicase; Helicase Superfamily I; I DNA/RNA Helicase

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MVPTDEQASVVDAVKAGGPLKVKAYAGAGKTSTLRLAAEARGRARGLYLAFNKDIANEAAQKFPQNTRCRTVHSLAYSAT
PPELTRKLKNPVEPPHQLALRYGLAKLRLPTTIGKDLELSASKVARIVMDGAARFCRSAQAEPLAWHIPVESIVKEEEAE
HLRDSLLPYVKRLWGEYLDPASPSAIVHDVYVKRWERSRPRIGADFILFDEAQDADGLMLSVLRAQQSQVIYVGDPYQQI
YEWRGAVNAMEHIRAPECALTESFRFGPAIAQLASRVLRLMDEETPVRGQDHVESRILHDSTPGQDRFDAILCRKNATVL
THLAQGIGRGDRVAVRANVDELRAFADGAEQLMRGQRIGYPATLALFETWEEVQEYAESFAGRDLKPLVTLIDNEGVDYL
RLILTRVSPEDEADYIVSTVHRAKGLEWERVQLAGDFKFKTGDDGELTMAPEEMRLLYVAMTRAKRLLDVSEIRRDLYTM
FREAGV

Sequences:

>Translated_486_residues
MVPTDEQASVVDAVKAGGPLKVKAYAGAGKTSTLRLAAEARGRARGLYLAFNKDIANEAAQKFPQNTRCRTVHSLAYSAT
PPELTRKLKNPVEPPHQLALRYGLAKLRLPTTIGKDLELSASKVARIVMDGAARFCRSAQAEPLAWHIPVESIVKEEEAE
HLRDSLLPYVKRLWGEYLDPASPSAIVHDVYVKRWERSRPRIGADFILFDEAQDADGLMLSVLRAQQSQVIYVGDPYQQI
YEWRGAVNAMEHIRAPECALTESFRFGPAIAQLASRVLRLMDEETPVRGQDHVESRILHDSTPGQDRFDAILCRKNATVL
THLAQGIGRGDRVAVRANVDELRAFADGAEQLMRGQRIGYPATLALFETWEEVQEYAESFAGRDLKPLVTLIDNEGVDYL
RLILTRVSPEDEADYIVSTVHRAKGLEWERVQLAGDFKFKTGDDGELTMAPEEMRLLYVAMTRAKRLLDVSEIRRDLYTM
FREAGV
>Mature_486_residues
MVPTDEQASVVDAVKAGGPLKVKAYAGAGKTSTLRLAAEARGRARGLYLAFNKDIANEAAQKFPQNTRCRTVHSLAYSAT
PPELTRKLKNPVEPPHQLALRYGLAKLRLPTTIGKDLELSASKVARIVMDGAARFCRSAQAEPLAWHIPVESIVKEEEAE
HLRDSLLPYVKRLWGEYLDPASPSAIVHDVYVKRWERSRPRIGADFILFDEAQDADGLMLSVLRAQQSQVIYVGDPYQQI
YEWRGAVNAMEHIRAPECALTESFRFGPAIAQLASRVLRLMDEETPVRGQDHVESRILHDSTPGQDRFDAILCRKNATVL
THLAQGIGRGDRVAVRANVDELRAFADGAEQLMRGQRIGYPATLALFETWEEVQEYAESFAGRDLKPLVTLIDNEGVDYL
RLILTRVSPEDEADYIVSTVHRAKGLEWERVQLAGDFKFKTGDDGELTMAPEEMRLLYVAMTRAKRLLDVSEIRRDLYTM
FREAGV

Specific function: Unknown

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI30795119, Length=508, Percent_Identity=29.5275590551181, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI30795117, Length=508, Percent_Identity=29.5275590551181, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54455; Mature: 54455

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPTDEQASVVDAVKAGGPLKVKAYAGAGKTSTLRLAAEARGRARGLYLAFNKDIANEAA
CCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHCCCCCEEEEEECHHHHHHHH
QKFPQNTRCRTVHSLAYSATPPELTRKLKNPVEPPHQLALRYGLAKLRLPTTIGKDLELS
HHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
ASKVARIVMDGAARFCRSAQAEPLAWHIPVESIVKEEEAEHLRDSLLPYVKRLWGEYLDP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASPSAIVHDVYVKRWERSRPRIGADFILFDEAQDADGLMLSVLRAQQSQVIYVGDPYQQI
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHH
YEWRGAVNAMEHIRAPECALTESFRFGPAIAQLASRVLRLMDEETPVRGQDHVESRILHD
HHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
STPGQDRFDAILCRKNATVLTHLAQGIGRGDRVAVRANVDELRAFADGAEQLMRGQRIGY
CCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCC
PATLALFETWEEVQEYAESFAGRDLKPLVTLIDNEGVDYLRLILTRVSPEDEADYIVSTV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
HRAKGLEWERVQLAGDFKFKTGDDGELTMAPEEMRLLYVAMTRAKRLLDVSEIRRDLYTM
HHHCCCCEEEEEEEECEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FREAGV
HHHCCC
>Mature Secondary Structure
MVPTDEQASVVDAVKAGGPLKVKAYAGAGKTSTLRLAAEARGRARGLYLAFNKDIANEAA
CCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHCCCCCEEEEEECHHHHHHHH
QKFPQNTRCRTVHSLAYSATPPELTRKLKNPVEPPHQLALRYGLAKLRLPTTIGKDLELS
HHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
ASKVARIVMDGAARFCRSAQAEPLAWHIPVESIVKEEEAEHLRDSLLPYVKRLWGEYLDP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASPSAIVHDVYVKRWERSRPRIGADFILFDEAQDADGLMLSVLRAQQSQVIYVGDPYQQI
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHH
YEWRGAVNAMEHIRAPECALTESFRFGPAIAQLASRVLRLMDEETPVRGQDHVESRILHD
HHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
STPGQDRFDAILCRKNATVLTHLAQGIGRGDRVAVRANVDELRAFADGAEQLMRGQRIGY
CCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCC
PATLALFETWEEVQEYAESFAGRDLKPLVTLIDNEGVDYLRLILTRVSPEDEADYIVSTV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
HRAKGLEWERVQLAGDFKFKTGDDGELTMAPEEMRLLYVAMTRAKRLLDVSEIRRDLYTM
HHHCCCCEEEEEEEECEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FREAGV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA