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The map label for this gene is yngJ [H]

Identifier: 38637886

GI number: 38637886

Start: 239335

End: 240561

Strand: Direct

Name: yngJ [H]

Synonym: PHG222

Alternate gene names: 38637886

Gene position: 239335-240561 (Clockwise)

Preceding gene: 38637885

Following gene: 38637892

Centisome position: 52.93

GC content: 64.71

Gene sequence:

>1227_bases
ATGCAATTCGAGTACACGCCGAAGGTCAAGGAGATGCAGGCCAAGCTGCTGGCCTTCTTCGAAAGGCACATCTATCCGAA
TGAACAGCGCTTCGAGGAGGAGATCGACGCTAACCGCCGCGCCGGCAATGCATGGATTCCCTCCACGGTGATCGACGAAC
TCAAGCCGCGGGCGCGCGAAGCCGGCCTGTGGAACCTTTTCCTGCCGCGTTCGCCGCGCGCCGCGCAGGGCCTGTCCAAC
CTCGAGTACGCACCGCTATGTGAGATCATGGGCCGCGTGCCCTGGTCGGCCGAGGTGTTCAACTGCTCGGCGCCCGACAC
CGGCAACATGGAAACGCTGGAGCGCTACGCCTCGGAAGAACTGAAGGACCAGTGGCTGGAGCCGCTGCTGGCCGGTGAAA
TCCGCTCGGCCTTCCTGATGACGGAGCCAGCCGTGGCCTCGTCGGACGCCACCAACATTGCCTGCCGCATCGAGCGCGAC
GGCGACCACTATGTGATCAACGGCACCAAGTGGTGGTCATCGGGCGCGGGCGACCCGCGCTGCAAGGTCTACATCGTGAT
GGGCAAGTCCAATCCCGACGCTGCCCGCCATGAGCAGCAGTCGATGATCGTGGTGCCGGCCGACGCGCCTGGCGTTACCG
TCAAACGCTTCGTTCCCGTGTTCGGCTACGACCATGCACCGCACGGCCACATGGAAATCGAGCTGAAGAACGTGCGCGTG
CCGGCTTCGAACATCCTGCTGGGCGAAGGCCGCGGCTTCGAGATGGCCCAGGGCCGCCTGGGCCCTGGCCGTATTCACCA
CTGCATGCGCAGCATCGGTGCGGCCGAGCGGACACTGGAACTGATGTGCAAGCGCAGCCTGGACCGCGTTGCCTTCGGCA
AGGAGATCGCCCGCCACGGCGTGACGCAGGAACGCATCGCCGAAGCCCGCTGCGAAATCGAAATGGCCCGCCTGCTCACA
CTCAAGGCGGGGTACATGATGGACACCGTGGGCAACAAGGTGGCCAAGGCCGAGATCGCCATGATCAAGGTGGTGGCCCC
AAACGTGGCGCTGAAGGTAATCGACTGGGCTATCCAGGTCCACGGCGCGGCCGGCGTGTCGAGCGACTTCCCGCTGGCCA
GCTGGTGGGCGCACCAGCGTACGCTGCGGCTGGCCGATGGTCCGGACGAGGTGCACCGCAACGCCATCGCCAAGCTTGAA
CTACTGAAGTACCGTTCGGATCGCTGA

Upstream 100 bases:

>100_bases
AGTCGTGATCGGAAGTCGATGAACGACCGAGCAAGCCAATTTGGTTACCAAGATCGGGATAAGCGTCACTTCCCTTCCAT
AATCTAGCGAGGGAATCGTC

Downstream 100 bases:

>100_bases
AGCGTAGGCGATTTCTTCAAGCCTCCCCCGCGCTAATCACGTTGTGGCGTGGGGAGGCGCTCATCCATGGAGCCCTTTGA
TTTCCGTGTAACGCGTGCCA

Product: acyl-coa dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQFEYTPKVKEMQAKLLAFFERHIYPNEQRFEEEIDANRRAGNAWIPSTVIDELKPRAREAGLWNLFLPRSPRAAQGLSN
LEYAPLCEIMGRVPWSAEVFNCSAPDTGNMETLERYASEELKDQWLEPLLAGEIRSAFLMTEPAVASSDATNIACRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKSNPDAARHEQQSMIVVPADAPGVTVKRFVPVFGYDHAPHGHMEIELKNVRV
PASNILLGEGRGFEMAQGRLGPGRIHHCMRSIGAAERTLELMCKRSLDRVAFGKEIARHGVTQERIAEARCEIEMARLLT
LKAGYMMDTVGNKVAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLASWWAHQRTLRLADGPDEVHRNAIAKLE
LLKYRSDR

Sequences:

>Translated_408_residues
MQFEYTPKVKEMQAKLLAFFERHIYPNEQRFEEEIDANRRAGNAWIPSTVIDELKPRAREAGLWNLFLPRSPRAAQGLSN
LEYAPLCEIMGRVPWSAEVFNCSAPDTGNMETLERYASEELKDQWLEPLLAGEIRSAFLMTEPAVASSDATNIACRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKSNPDAARHEQQSMIVVPADAPGVTVKRFVPVFGYDHAPHGHMEIELKNVRV
PASNILLGEGRGFEMAQGRLGPGRIHHCMRSIGAAERTLELMCKRSLDRVAFGKEIARHGVTQERIAEARCEIEMARLLT
LKAGYMMDTVGNKVAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLASWWAHQRTLRLADGPDEVHRNAIAKLE
LLKYRSDR
>Mature_408_residues
MQFEYTPKVKEMQAKLLAFFERHIYPNEQRFEEEIDANRRAGNAWIPSTVIDELKPRAREAGLWNLFLPRSPRAAQGLSN
LEYAPLCEIMGRVPWSAEVFNCSAPDTGNMETLERYASEELKDQWLEPLLAGEIRSAFLMTEPAVASSDATNIACRIERD
GDHYVINGTKWWSSGAGDPRCKVYIVMGKSNPDAARHEQQSMIVVPADAPGVTVKRFVPVFGYDHAPHGHMEIELKNVRV
PASNILLGEGRGFEMAQGRLGPGRIHHCMRSIGAAERTLELMCKRSLDRVAFGKEIARHGVTQERIAEARCEIEMARLLT
LKAGYMMDTVGNKVAKAEIAMIKVVAPNVALKVIDWAIQVHGAAGVSSDFPLASWWAHQRTLRLADGPDEVHRNAIAKLE
LLKYRSDR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=56.6084788029925, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI211971008, Length=400, Percent_Identity=53.5, Blast_Score=433, Evalue=1e-121,
Organism=Homo sapiens, GI48976061, Length=400, Percent_Identity=53.5, Blast_Score=433, Evalue=1e-121,
Organism=Homo sapiens, GI4557231, Length=415, Percent_Identity=25.5421686746988, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=28.8359788359788, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI187960098, Length=415, Percent_Identity=25.5421686746988, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI4557233, Length=345, Percent_Identity=28.695652173913, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4501859, Length=322, Percent_Identity=27.9503105590062, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7656849, Length=391, Percent_Identity=24.8081841432225, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI76496475, Length=413, Percent_Identity=25.4237288135593, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=413, Percent_Identity=25.4237288135593, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226958412, Length=390, Percent_Identity=23.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=326, Percent_Identity=24.5398773006135, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=24.9201277955272, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4503943, Length=318, Percent_Identity=23.8993710691824, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7669494, Length=296, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081958, Length=305, Percent_Identity=26.5573770491803, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786223, Length=298, Percent_Identity=22.1476510067114, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=361, Percent_Identity=53.7396121883656, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534899, Length=403, Percent_Identity=27.2952853598015, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17569725, Length=410, Percent_Identity=27.5609756097561, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=284, Percent_Identity=29.2253521126761, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71985184, Length=377, Percent_Identity=27.8514588859416, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=292, Percent_Identity=28.4246575342466, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=284, Percent_Identity=29.9295774647887, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=415, Percent_Identity=26.0240963855422, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=24.6073298429319, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=312, Percent_Identity=26.6025641025641, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=288, Percent_Identity=27.0833333333333, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=313, Percent_Identity=26.517571884984, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=28.0952380952381, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=279, Percent_Identity=25.089605734767, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=184, Percent_Identity=26.6304347826087, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=24.7933884297521, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646207, Length=352, Percent_Identity=29.2613636363636, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363737, Length=396, Percent_Identity=27.5252525252525, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=31.25, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24660351, Length=284, Percent_Identity=29.9295774647887, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356377, Length=347, Percent_Identity=28.2420749279539, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355753, Length=291, Percent_Identity=25.7731958762887, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920834, Length=321, Percent_Identity=26.1682242990654, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45668; Mature: 45668

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFEYTPKVKEMQAKLLAFFERHIYPNEQRFEEEIDANRRAGNAWIPSTVIDELKPRARE
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHH
AGLWNLFLPRSPRAAQGLSNLEYAPLCEIMGRVPWSAEVFNCSAPDTGNMETLERYASEE
CCEEEEECCCCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
LKDQWLEPLLAGEIRSAFLMTEPAVASSDATNIACRIERDGDHYVINGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKSNPDAARHEQQSMIVVPADAPGVTVKRFVPVFGYDHAPHGHMEIELKNVRV
EEEEEEEECCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEEC
PASNILLGEGRGFEMAQGRLGPGRIHHCMRSIGAAERTLELMCKRSLDRVAFGKEIARHG
CHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTQERIAEARCEIEMARLLTLKAGYMMDTVGNKVAKAEIAMIKVVAPNVALKVIDWAIQV
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHEEEEEEECCCHHEEEEEEEEEE
HGAAGVSSDFPLASWWAHQRTLRLADGPDEVHRNAIAKLELLKYRSDR
ECCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQFEYTPKVKEMQAKLLAFFERHIYPNEQRFEEEIDANRRAGNAWIPSTVIDELKPRARE
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHH
AGLWNLFLPRSPRAAQGLSNLEYAPLCEIMGRVPWSAEVFNCSAPDTGNMETLERYASEE
CCEEEEECCCCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
LKDQWLEPLLAGEIRSAFLMTEPAVASSDATNIACRIERDGDHYVINGTKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCEEEEECEEECCCCCCCCC
CKVYIVMGKSNPDAARHEQQSMIVVPADAPGVTVKRFVPVFGYDHAPHGHMEIELKNVRV
EEEEEEEECCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEEC
PASNILLGEGRGFEMAQGRLGPGRIHHCMRSIGAAERTLELMCKRSLDRVAFGKEIARHG
CHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VTQERIAEARCEIEMARLLTLKAGYMMDTVGNKVAKAEIAMIKVVAPNVALKVIDWAIQV
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHEEEEEEECCCHHEEEEEEEEEE
HGAAGVSSDFPLASWWAHQRTLRLADGPDEVHRNAIAKLELLKYRSDR
ECCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]