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The map label for this gene is hoxJ [H]

Identifier: 38637690

GI number: 38637690

Start: 19533

End: 20933

Strand: Direct

Name: hoxJ [H]

Synonym: PHG022

Alternate gene names: 38637690

Gene position: 19533-20933 (Clockwise)

Preceding gene: 38637689

Following gene: 38637691

Centisome position: 4.32

GC content: 59.31

Gene sequence:

>1401_bases
ATGTCCAGTAAGAGGACCACTACATCAAGCGGGAGTCACGGCGTCGATCTGGACGCCATGACACCATCGCAACTCGAGGG
TATCGACGAAGCGACCTGGCTGGACGTGATCCGCAAAATGGACGAGGTCTACCTGCAATTGATAGAGGACGAAGTAGCGC
TGGAGGAAAAGAACGCTCAACTGGAGCAGTCCCAGCAATTCATCTTCAGCCTGCTTTCGGCGATGTCGGACGTACTGGTT
GCTTGCAATGCGCGTGGCGAAATAGAGGAGACCAATGTGGCGCTGCGCGAACTGGTAGGCATGCAGGAGAGCGCTCTGCA
CGGCATGTCGATTTATCAGTTGCTGGCCGACGACGACAGCGCCGCGACGTTGCGCACGGTGATCGACAATGTGGGGCCTG
GCCGGAGTTTCAACGTTGTCGAGCTAAATCTGTTCGATGCCGAACGCAGCATCGTGCCGGTGGACGTCAGTTGCACGCCC
CGTATCGGTCCGAATGGCAGGCGTGAAGGCTATGTTTTCGTGGGTCGCCCAATGGCCGAGATCAAACGTGCCTATCATCA
ATTGCGCGAGGCGCACGAGGCACTCAAGCGTACGCAGCAGCAACTGCTGCATGCGGAAAAGATGGCATCACTCGGGCGCC
TTGTCGCTGGGGTGGCGCACGAGTTGAACAATCCAATCAGCTTCGTGCTGGGGAATGTGCACGCGCTTAAGCGCTACAGC
GAACGCCTCGCAGCCTACGTGGCATTGCTGCATAGCGGAGAGGATGGCGCTGAAGCCGAGCGCCAGCGGATTCGCTTGCG
CATCGATCATATTCTGCAGGATATGCCGTCGTTGATAGAAGGGACGCTCGAGGGCGCGCAGCGCACTGCCGACATCGTGC
GTGGCCTGACGCGCTTTTCCGCTGTGGATCGTGAAGAGCCAAGCGTGTTCGATTTGAGCGAAGTGGTGAAAAGGGCCATT
CACTGGGTGAAGAAAGGAACTGCGCCGACTTTCGAAGTCCATTGGTCACCGCTACCGGGATGCCTGGTGATGGGCAGCGC
CGGGCACGTGCAGCAGGTAATGATGAATCTGATTCAGAATGCCTACGATGCGGCGGGGAGCCGTGACGATGCCGTTCCGG
CATTGTGGATCGCCTTGGACCGACTCGACGACCGGGTCGTGCTGCGCTTTCGAGACAACGGTCCCGGCATTGCGGCTGAA
CACCTGGCCCGCGTGTTCGATCCATTCTTCAGCACCAAGCCTGTTGGCAAGGGGACTGGGCTTAGTCTTTCGATCAGCTA
TGGCATTGTCGAGAGACATGGCGGGCGCTTGCTCGTCCGCAACCACCCGGAGGGCGGCGCGGAGTTCACGGTCGAACTGC
CAGCTGCTCACGACAAGGGGTCGTCCGCAGACCGGCGTTGA

Upstream 100 bases:

>100_bases
AGCATGCACCTCAATCACCACGATCATATGGCACGGGCAAGCCGAAGCCGACGTGGCAACGTTGCGTCGCATCCTCGGGC
ACCTGATTGCCATTATCGCC

Downstream 100 bases:

>100_bases
TCGGTTGCCGGGGCCCGGCTCCGCCCGTGTTCCGGGGAACGCCTGTTCGAAATTGGCGGAGGCAGGAGGCTGATGGCCTG
ATTTCCCTGCTGCACCAGGC

Product: histidine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSSKRTTTSSGSHGVDLDAMTPSQLEGIDEATWLDVIRKMDEVYLQLIEDEVALEEKNAQLEQSQQFIFSLLSAMSDVLV
ACNARGEIEETNVALRELVGMQESALHGMSIYQLLADDDSAATLRTVIDNVGPGRSFNVVELNLFDAERSIVPVDVSCTP
RIGPNGRREGYVFVGRPMAEIKRAYHQLREAHEALKRTQQQLLHAEKMASLGRLVAGVAHELNNPISFVLGNVHALKRYS
ERLAAYVALLHSGEDGAEAERQRIRLRIDHILQDMPSLIEGTLEGAQRTADIVRGLTRFSAVDREEPSVFDLSEVVKRAI
HWVKKGTAPTFEVHWSPLPGCLVMGSAGHVQQVMMNLIQNAYDAAGSRDDAVPALWIALDRLDDRVVLRFRDNGPGIAAE
HLARVFDPFFSTKPVGKGTGLSLSISYGIVERHGGRLLVRNHPEGGAEFTVELPAAHDKGSSADRR

Sequences:

>Translated_466_residues
MSSKRTTTSSGSHGVDLDAMTPSQLEGIDEATWLDVIRKMDEVYLQLIEDEVALEEKNAQLEQSQQFIFSLLSAMSDVLV
ACNARGEIEETNVALRELVGMQESALHGMSIYQLLADDDSAATLRTVIDNVGPGRSFNVVELNLFDAERSIVPVDVSCTP
RIGPNGRREGYVFVGRPMAEIKRAYHQLREAHEALKRTQQQLLHAEKMASLGRLVAGVAHELNNPISFVLGNVHALKRYS
ERLAAYVALLHSGEDGAEAERQRIRLRIDHILQDMPSLIEGTLEGAQRTADIVRGLTRFSAVDREEPSVFDLSEVVKRAI
HWVKKGTAPTFEVHWSPLPGCLVMGSAGHVQQVMMNLIQNAYDAAGSRDDAVPALWIALDRLDDRVVLRFRDNGPGIAAE
HLARVFDPFFSTKPVGKGTGLSLSISYGIVERHGGRLLVRNHPEGGAEFTVELPAAHDKGSSADRR
>Mature_465_residues
SSKRTTTSSGSHGVDLDAMTPSQLEGIDEATWLDVIRKMDEVYLQLIEDEVALEEKNAQLEQSQQFIFSLLSAMSDVLVA
CNARGEIEETNVALRELVGMQESALHGMSIYQLLADDDSAATLRTVIDNVGPGRSFNVVELNLFDAERSIVPVDVSCTPR
IGPNGRREGYVFVGRPMAEIKRAYHQLREAHEALKRTQQQLLHAEKMASLGRLVAGVAHELNNPISFVLGNVHALKRYSE
RLAAYVALLHSGEDGAEAERQRIRLRIDHILQDMPSLIEGTLEGAQRTADIVRGLTRFSAVDREEPSVFDLSEVVKRAIH
WVKKGTAPTFEVHWSPLPGCLVMGSAGHVQQVMMNLIQNAYDAAGSRDDAVPALWIALDRLDDRVVLRFRDNGPGIAAEH
LARVFDPFFSTKPVGKGTGLSLSISYGIVERHGGRLLVRNHPEGGAEFTVELPAAHDKGSSADRR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=381, Percent_Identity=24.6719160104987, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=27.6119402985075, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=129, Percent_Identity=34.1085271317829, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=260, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51307; Mature: 51176

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKRTTTSSGSHGVDLDAMTPSQLEGIDEATWLDVIRKMDEVYLQLIEDEVALEEKNAQ
CCCCCCCCCCCCCCCEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQSQQFIFSLLSAMSDVLVACNARGEIEETNVALRELVGMQESALHGMSIYQLLADDDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
AATLRTVIDNVGPGRSFNVVELNLFDAERSIVPVDVSCTPRIGPNGRREGYVFVGRPMAE
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEECCCHHH
IKRAYHQLREAHEALKRTQQQLLHAEKMASLGRLVAGVAHELNNPISFVLGNVHALKRYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
ERLAAYVALLHSGEDGAEAERQRIRLRIDHILQDMPSLIEGTLEGAQRTADIVRGLTRFS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDREEPSVFDLSEVVKRAIHWVKKGTAPTFEVHWSPLPGCLVMGSAGHVQQVMMNLIQN
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHH
AYDAAGSRDDAVPALWIALDRLDDRVVLRFRDNGPGIAAEHLARVFDPFFSTKPVGKGTG
HHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LSLSISYGIVERHGGRLLVRNHPEGGAEFTVELPAAHDKGSSADRR
EEEEEEECHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SSKRTTTSSGSHGVDLDAMTPSQLEGIDEATWLDVIRKMDEVYLQLIEDEVALEEKNAQ
CCCCCCCCCCCCCCEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQSQQFIFSLLSAMSDVLVACNARGEIEETNVALRELVGMQESALHGMSIYQLLADDDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
AATLRTVIDNVGPGRSFNVVELNLFDAERSIVPVDVSCTPRIGPNGRREGYVFVGRPMAE
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEECCCHHH
IKRAYHQLREAHEALKRTQQQLLHAEKMASLGRLVAGVAHELNNPISFVLGNVHALKRYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
ERLAAYVALLHSGEDGAEAERQRIRLRIDHILQDMPSLIEGTLEGAQRTADIVRGLTRFS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDREEPSVFDLSEVVKRAIHWVKKGTAPTFEVHWSPLPGCLVMGSAGHVQQVMMNLIQN
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHH
AYDAAGSRDDAVPALWIALDRLDDRVVLRFRDNGPGIAAEHLARVFDPFFSTKPVGKGTG
HHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LSLSISYGIVERHGGRLLVRNHPEGGAEFTVELPAAHDKGSSADRR
EEEEEEECHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]