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The map label for this gene is hoxB [C]

Identifier: 38637688

GI number: 38637688

Start: 16923

End: 17966

Strand: Direct

Name: hoxB [C]

Synonym: PHG020

Alternate gene names: 38637688

Gene position: 16923-17966 (Clockwise)

Preceding gene: 38637687

Following gene: 38637689

Centisome position: 3.74

GC content: 61.21

Gene sequence:

>1044_bases
ATGAACGCGCCTGTATGTACCGGTCTTGCCTCAGCAAAACCCGGCGTATTGAATGTGCTCTGGATACAGTCCGGCGGCTG
CGGTGGCTGCAGCATGTCCCTGCTTTGCGCGGACACTACCGATTTCACTGGCATGCTCAAGAGTGCGGGAATCCACATGC
TTTGGCATCCCTCGCTATCGCTGGAAAGCGGCGTGGAACAGCTGCAAATATTGGAAGACTGCTTGCAAGGCCGCGTCGCA
CTGCATGCCTTGTGTGTCGAGGGGGCGATGCTGCGCGGTCCGCATGGTACCGGGCGCTTTCATCTCCTCGCCGGCACTGG
TGTGCCGATGATCGAATGGGTCAGCCGCCTGGCAGCGGTCGCCGACTACACGCTGGCGGTCGGCACCTGTGCCGCTTATG
GCGGCATCACCGCAGGTGGCGGGAACCCGACGGACGCCTGTGGCCTGCAATACGAGGGGGACCAGCCCGGAGGACTGCTC
GGCCTCAACTACCGCTCACGCGCCGGCCTGCCGGTGATCAATGTCGCCGGTTGCCCGACGCATCCGGGTTGGGTGACGGA
TGCACTGGCATTGCTGTCGGCTCGCCTGCTAACCGCGAGCGACCTGGATACCCTGGGCCGGCCTCGATTCTATGCTGATC
AGTTGGTGCATCACGGTTGCACGCGCAACGAGTACTATGAATTCAAGGCTAGTGCGGAAAAGCCTTCGGACCTGGGTTGC
ATGATGGAAAACATGGGATGCAAGGGTACCCAGGCTCACGCCGATTGCAATACCCGCCTATGGAACGGAGAGGGTTCCTG
TACCCGCGGGGGGTATGCCTGCATCAGTTGCACTGAACCCGGCTTCGAAGAGCCCGGCCACCCCTTCCACCAAACACCCA
AGGTTGCCGGCATCCCGATCGGTTTGCCCACCGATATGCCCAAAGCCTGGTTTGTCGCGCTTGCTTCGTTGTCCAAGTCA
GCCACGCCCAAGCGAGTGAAACTTAATGCCACGGCAGATCATCCGCTGATCGCGCCAGCCATTCGCAAGACGCGGCTGAA
ATAG

Upstream 100 bases:

>100_bases
TCCTGCGCCATCGTTGGAACAAGACCCATGCGGCCAAGGAGTTGGGTCTATCGCGCGTCGGATTACGTCAGAAGCTGTTG
CGCTTTGGCTTGGAGGAGAA

Downstream 100 bases:

>100_bases
GAGGCGAGCATGGAACGTTTGGTGGTGGGGCCGTTCAACCGCGTTGAGGGCGACCTCGAGGTGAACCTCGAGGTCGCCAG
CGGTCGGGTATGCTCAGCAC

Product: regulatory [NiFe] hydrogenase small subunit

Products: NA

Alternate protein names: NiFeSe hydrogenlyase small chain [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNAPVCTGLASAKPGVLNVLWIQSGGCGGCSMSLLCADTTDFTGMLKSAGIHMLWHPSLSLESGVEQLQILEDCLQGRVA
LHALCVEGAMLRGPHGTGRFHLLAGTGVPMIEWVSRLAAVADYTLAVGTCAAYGGITAGGGNPTDACGLQYEGDQPGGLL
GLNYRSRAGLPVINVAGCPTHPGWVTDALALLSARLLTASDLDTLGRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGC
MMENMGCKGTQAHADCNTRLWNGEGSCTRGGYACISCTEPGFEEPGHPFHQTPKVAGIPIGLPTDMPKAWFVALASLSKS
ATPKRVKLNATADHPLIAPAIRKTRLK

Sequences:

>Translated_347_residues
MNAPVCTGLASAKPGVLNVLWIQSGGCGGCSMSLLCADTTDFTGMLKSAGIHMLWHPSLSLESGVEQLQILEDCLQGRVA
LHALCVEGAMLRGPHGTGRFHLLAGTGVPMIEWVSRLAAVADYTLAVGTCAAYGGITAGGGNPTDACGLQYEGDQPGGLL
GLNYRSRAGLPVINVAGCPTHPGWVTDALALLSARLLTASDLDTLGRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGC
MMENMGCKGTQAHADCNTRLWNGEGSCTRGGYACISCTEPGFEEPGHPFHQTPKVAGIPIGLPTDMPKAWFVALASLSKS
ATPKRVKLNATADHPLIAPAIRKTRLK
>Mature_347_residues
MNAPVCTGLASAKPGVLNVLWIQSGGCGGCSMSLLCADTTDFTGMLKSAGIHMLWHPSLSLESGVEQLQILEDCLQGRVA
LHALCVEGAMLRGPHGTGRFHLLAGTGVPMIEWVSRLAAVADYTLAVGTCAAYGGITAGGGNPTDACGLQYEGDQPGGLL
GLNYRSRAGLPVINVAGCPTHPGWVTDALALLSARLLTASDLDTLGRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGC
MMENMGCKGTQAHADCNTRLWNGEGSCTRGGYACISCTEPGFEEPGHPFHQTPKVAGIPIGLPTDMPKAWFVALASLSKS
ATPKRVKLNATADHPLIAPAIRKTRLK

Specific function: This Is One Of Three E.Coli Hydrogenases Synthesized In Response To Different Physiological Conditions. Hyd1 Is Believed To Have A Role In Hydrogen Cycling During Fermentative Growth. [C]

COG id: COG1740

COG function: function code C; Ni,Fe-hydrogenase I small subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family [H]

Homologues:

Organism=Escherichia coli, GI1787206, Length=302, Percent_Identity=27.1523178807947, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789371, Length=274, Percent_Identity=27.7372262773723, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR001821
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.12.99.6 [H]

Molecular weight: Translated: 36501; Mature: 36501

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00277 STAPH_STREP_TOXIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPVCTGLASAKPGVLNVLWIQSGGCGGCSMSLLCADTTDFTGMLKSAGIHMLWHPSLS
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHCCEEEEECCCCC
LESGVEQLQILEDCLQGRVALHALCVEGAMLRGPHGTGRFHLLAGTGVPMIEWVSRLAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHH
ADYTLAVGTCAAYGGITAGGGNPTDACGLQYEGDQPGGLLGLNYRSRAGLPVINVAGCPT
HHHHHHHHHHHHHCCEECCCCCCCCCCCCEECCCCCCCEEECCCCCCCCCCEEEECCCCC
HPGWVTDALALLSARLLTASDLDTLGRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGC
CCCHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
MMENMGCKGTQAHADCNTRLWNGEGSCTRGGYACISCTEPGFEEPGHPFHQTPKVAGIPI
HHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEC
GLPTDMPKAWFVALASLSKSATPKRVKLNATADHPLIAPAIRKTRLK
CCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHHHCCC
>Mature Secondary Structure
MNAPVCTGLASAKPGVLNVLWIQSGGCGGCSMSLLCADTTDFTGMLKSAGIHMLWHPSLS
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHCCEEEEECCCCC
LESGVEQLQILEDCLQGRVALHALCVEGAMLRGPHGTGRFHLLAGTGVPMIEWVSRLAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHH
ADYTLAVGTCAAYGGITAGGGNPTDACGLQYEGDQPGGLLGLNYRSRAGLPVINVAGCPT
HHHHHHHHHHHHHCCEECCCCCCCCCCCCEECCCCCCCEEECCCCCCCCCCEEEECCCCC
HPGWVTDALALLSARLLTASDLDTLGRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGC
CCCHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
MMENMGCKGTQAHADCNTRLWNGEGSCTRGGYACISCTEPGFEEPGHPFHQTPKVAGIPI
HHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEC
GLPTDMPKAWFVALASLSKSATPKRVKLNATADHPLIAPAIRKTRLK
CCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3316183; 3322275; 10378275 [H]