Click here to switch to the map view.

The map label for this gene is hoxM

Identifier: 38637673

GI number: 38637673

Start: 4282

End: 4890

Strand: Direct

Name: hoxM

Synonym: PHG005

Alternate gene names: 38637673

Gene position: 4282-4890 (Clockwise)

Preceding gene: 38637672

Following gene: 38637674

Centisome position: 0.95

GC content: 62.07

Gene sequence:

>609_bases
GTGGTAGTTGCAATGGGCATTGGCAATGTGCTCTGGGCGGATGAGGGCTTTGGCGTGCGCTGCATTGAAACCCTCCAGCA
GCGCTATCAGTTCGCACCGCAGGTATGCCTGGTCGACGGGGGCACGCAGGGGCTCTATCTGATCCACCACGTGCAGGCTG
CGTCGCGCCTGCTGATCTTCGATGCGATCGACTATGGCCTGCCTCCAGGAACGCTGAGAATTATCGAAGACGAGGCGGTG
CCGAAATTCCTTGGGGCCAAGAAGATGAGCCTGCACCAGACCGGCTTCCAGGAAGTACTGTTGCTCGCCCAGTTGACGGG
ACAGTACCCGCAGCAGGTGGTGCTGATCGGCTGTCAGCCGGAGGAGTTGGAGGATTATGGCGGCAGTCTAAGGCGGGTGA
TGAAGGCTGCGGTGGAGGATGCGGTGGAGAAAGGGGCGGACTTGCTGCGGAGATGGGGCGGGATGCCGGTGCCTCGCACT
GCGGAGCTTGCGCCTGCCGAGGCCGTGACCGTGCCGCATCTGGCGCTCGATCGCTACGAAGCCGAACGTCCTTCGCCTCG
GGCCGCCTGCCGGATTGGCGATGAACGTTTTATGCCACAGGATTTGTGA

Upstream 100 bases:

>100_bases
TACACGGTTCCCTTTTTCGCTGACCACCGCCATGAGACCAACTCAAACGTCCGATATCGCACCTGGAACCAGCTGTAACC
AATCCCGTGACAAGGAGCCG

Downstream 100 bases:

>100_bases
GGGGCGAATATGTGTATTGGCATTCCCATGCAGGTCATGGCGATCGAGCCTGGATATGCGGTCTGTGCGGGACGCGGCGA
ACGACGGAGAGTCTCGAGCG

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIFDAIDYGLPPGTLRIIEDEAV
PKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQPEELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRT
AELAPAEAVTVPHLALDRYEAERPSPRAACRIGDERFMPQDL

Sequences:

>Translated_202_residues
MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIFDAIDYGLPPGTLRIIEDEAV
PKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQPEELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRT
AELAPAEAVTVPHLALDRYEAERPSPRAACRIGDERFMPQDL
>Mature_202_residues
MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIFDAIDYGLPPGTLRIIEDEAV
PKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQPEELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRT
AELAPAEAVTVPHLALDRYEAERPSPRAACRIGDERFMPQDL

Specific function: Absolutely required for hydrogenase activity. Mediates the attachment of hydrogenase to the bacterial membrane; attachment is a requirement for enzymatic activity

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family

Homologues:

Organism=Escherichia coli, GI1787209, Length=182, Percent_Identity=47.8021978021978, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1789367, Length=161, Percent_Identity=38.5093167701863, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HOXM_CUPNH (P31909)

Other databases:

- EMBL:   M96433
- EMBL:   AY305378
- PIR:   E43255
- RefSeq:   NP_942647.1
- ProteinModelPortal:   P31909
- SMR:   P31909
- MEROPS:   A31.002
- GeneID:   2656808
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG005
- HOGENOM:   HBG730505
- OMA:   IRERETP
- PhylomeDB:   P31909
- ProtClustDB:   CLSK923791
- BioCyc:   REUT381666:PHG005-MONOMER
- InterPro:   IPR004419
- InterPro:   IPR000671
- Gene3D:   G3DSA:3.40.50.1450
- PRINTS:   PR00446
- TIGRFAMs:   TIGR00140
- TIGRFAMs:   TIGR00072

Pfam domain/function: PF01750 HycI

EC number: 3.4.24.- [C]

Molecular weight: Translated: 22254; Mature: 22254

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIF
CEEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHHHHHHHHEE
DAIDYGLPPGTLRIIEDEAVPKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQP
EHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCH
EELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRTAELAPAEAVTVPHLALDRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AERPSPRAACRIGDERFMPQDL
CCCCCCHHHEECCCCCCCCCCC
>Mature Secondary Structure
MVVAMGIGNVLWADEGFGVRCIETLQQRYQFAPQVCLVDGGTQGLYLIHHVQAASRLLIF
CEEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHHHHHHHHEE
DAIDYGLPPGTLRIIEDEAVPKFLGAKKMSLHQTGFQEVLLLAQLTGQYPQQVVLIGCQP
EHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCH
EELEDYGGSLRRVMKAAVEDAVEKGADLLRRWGGMPVPRTAELAPAEAVTVPHLALDRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AERPSPRAACRIGDERFMPQDL
CCCCCCHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1383192; 12948488