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The map label for this gene is hoxK

Identifier: 38637669

GI number: 38637669

Start: 115

End: 1197

Strand: Direct

Name: hoxK

Synonym: PHG001

Alternate gene names: 38637669

Gene position: 115-1197 (Clockwise)

Preceding gene: NA

Following gene: 38637670

Centisome position: 0.03

GC content: 57.53

Gene sequence:

>1083_bases
ATGGTCGAAACATTTTATGAAGTCATGCGCAGGCAGGGCATTTCGCGACGAAGTTTCCTGAAGTACTGTTCCCTGACAGC
CACATCCTTAGGACTGGGACCTTCCTTTCTGCCGCAGATCGCGCACGCGATGGAAACCAAGCCGCGTACACCAGTACTTT
GGCTGCACGGTCTCGAATGTACCTGTTGCTCGGAATCGTTCATTCGCTCGGCCCATCCGCTGGCAAAGGACGTCGTGCTA
TCGATGATCTCACTGGACTATGACGACACACTGATGGCGGCTGCCGGCCACCAGGCCGAGGCCATCCTCGAGGAGATCAT
GACGAAGTACAAGGGCAACTATATTCTGGCGGTGGAGGGGAATCCGCCACTCAATCAGGATGGCATGAGCTGCATCATCG
GTGGGCGGCCATTCATTGAGCAGCTCAAATACGTGGCCAAGGATGCCAAGGCCATTATCTCCTGGGGTTCCTGCGCATCC
TGGGGATGCGTGCAGGCAGCCAAACCTAATCCCACTCAGGCCACACCGGTTCACAAGGTGATCACCGACAAGCCGATTAT
CAAGGTCCCGGGGTGCCCTCCGATTGCCGAAGTGATGACGGGTGTCATTACCTACATGCTCACCTTCGATCGTATTCCCG
AACTGGATCGACAGGGTCGGCCGAAGATGTTCTATAGCCAGCGCATCCACGACAAATGCTACCGGCGTCCACACTTCGAT
GCCGGCCAGTTCGTCGAGGAATGGGACGACGAATCAGCCCGCAAAGGCTTCTGCTTATACAAGATGGGCTGTAAAGGCCC
GACCACGTACAACGCCTGCTCCACCACGCGCTGGAACGAGGGGACGAGTTTCCCCATTCAGTCGGGCCACGGTTGCATTG
GTTGCTCCGAGGATGGCTTTTGGGACAAAGGCTCATTCTACGATCGTCTGACCGGCATCAGCCAGTTCGGCGTTGAGGCC
AACGCCGACAAGATTGGCGGAACGGCCTCCGTCGTGGTGGGGGCGGCCGTGACGGCGCATGCCGCAGCGTCTGCGATCAA
GCGTGCGTCGAAGAAGAACGAAACCAGCGGCAGTGAACACTAA

Upstream 100 bases:

>100_bases
TATGTCGCCAAGCCAGCATTCGTGCGCGAGGGCGGTATCGCTCCCCGGTTGGCGCATCGCGACGAATGCCAATACCAATA
CAGAAATTAGGAGACAGGTT

Downstream 100 bases:

>100_bases
GCCGCCGGGGAAACGACTGAATCAGGAAGATCGAAATAATGTCAGCTTACGCAACCCAAGGCTTCAATCTTGACGACCGC
GGCCGTCGCATTGTCGTCGA

Product: membrane-bound [NiFe] hydrogenase small subunit

Products: NA

Alternate protein names: Hydrogenlyase; Membrane-bound hydrogenase small subunit

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MVETFYEVMRRQGISRRSFLKYCSLTATSLGLGPSFLPQIAHAMETKPRTPVLWLHGLECTCCSESFIRSAHPLAKDVVL
SMISLDYDDTLMAAAGHQAEAILEEIMTKYKGNYILAVEGNPPLNQDGMSCIIGGRPFIEQLKYVAKDAKAIISWGSCAS
WGCVQAAKPNPTQATPVHKVITDKPIIKVPGCPPIAEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFD
AGQFVEEWDDESARKGFCLYKMGCKGPTTYNACSTTRWNEGTSFPIQSGHGCIGCSEDGFWDKGSFYDRLTGISQFGVEA
NADKIGGTASVVVGAAVTAHAAASAIKRASKKNETSGSEH

Sequences:

>Translated_360_residues
MVETFYEVMRRQGISRRSFLKYCSLTATSLGLGPSFLPQIAHAMETKPRTPVLWLHGLECTCCSESFIRSAHPLAKDVVL
SMISLDYDDTLMAAAGHQAEAILEEIMTKYKGNYILAVEGNPPLNQDGMSCIIGGRPFIEQLKYVAKDAKAIISWGSCAS
WGCVQAAKPNPTQATPVHKVITDKPIIKVPGCPPIAEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFD
AGQFVEEWDDESARKGFCLYKMGCKGPTTYNACSTTRWNEGTSFPIQSGHGCIGCSEDGFWDKGSFYDRLTGISQFGVEA
NADKIGGTASVVVGAAVTAHAAASAIKRASKKNETSGSEH
>Mature_360_residues
MVETFYEVMRRQGISRRSFLKYCSLTATSLGLGPSFLPQIAHAMETKPRTPVLWLHGLECTCCSESFIRSAHPLAKDVVL
SMISLDYDDTLMAAAGHQAEAILEEIMTKYKGNYILAVEGNPPLNQDGMSCIIGGRPFIEQLKYVAKDAKAIISWGSCAS
WGCVQAAKPNPTQATPVHKVITDKPIIKVPGCPPIAEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFD
AGQFVEEWDDESARKGFCLYKMGCKGPTTYNACSTTRWNEGTSFPIQSGHGCIGCSEDGFWDKGSFYDRLTGISQFGVEA
NADKIGGTASVVVGAAVTAHAAASAIKRASKKNETSGSEH

Specific function: This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions

COG id: COG1740

COG function: function code C; Ni,Fe-hydrogenase I small subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family

Homologues:

Organism=Escherichia coli, GI1787206, Length=327, Percent_Identity=74.3119266055046, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1789371, Length=294, Percent_Identity=41.4965986394558, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MBHS_CUPNH (P31892)

Other databases:

- EMBL:   M96433
- EMBL:   AY305378
- PIR:   A43255
- RefSeq:   NP_942643.1
- ProteinModelPortal:   P31892
- SMR:   P31892
- GeneID:   2656804
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG001
- HOGENOM:   HBG575615
- OMA:   MASAGHQ
- PhylomeDB:   P31892
- ProtClustDB:   CLSK923788
- BioCyc:   MetaCyc:HOXKALCA-MONOMER
- BioCyc:   REUT381666:PHG001-MONOMER
- InterPro:   IPR006137
- InterPro:   IPR001821
- InterPro:   IPR006311
- PIRSF:   PIRSF000310
- PRINTS:   PR00614
- TIGRFAMs:   TIGR00391
- TIGRFAMs:   TIGR01409

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.12.99.6

Molecular weight: Translated: 39473; Mature: 39473

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETFYEVMRRQGISRRSFLKYCSLTATSLGLGPSFLPQIAHAMETKPRTPVLWLHGLEC
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
TCCSESFIRSAHPLAKDVVLSMISLDYDDTLMAAAGHQAEAILEEIMTKYKGNYILAVEG
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECC
NPPLNQDGMSCIIGGRPFIEQLKYVAKDAKAIISWGSCASWGCVQAAKPNPTQATPVHKV
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
ITDKPIIKVPGCPPIAEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFD
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
AGQFVEEWDDESARKGFCLYKMGCKGPTTYNACSTTRWNEGTSFPIQSGHGCIGCSEDGF
HHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
WDKGSFYDRLTGISQFGVEANADKIGGTASVVVGAAVTAHAAASAIKRASKKNETSGSEH
CCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVETFYEVMRRQGISRRSFLKYCSLTATSLGLGPSFLPQIAHAMETKPRTPVLWLHGLEC
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
TCCSESFIRSAHPLAKDVVLSMISLDYDDTLMAAAGHQAEAILEEIMTKYKGNYILAVEG
CHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECC
NPPLNQDGMSCIIGGRPFIEQLKYVAKDAKAIISWGSCASWGCVQAAKPNPTQATPVHKV
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
ITDKPIIKVPGCPPIAEVMTGVITYMLTFDRIPELDRQGRPKMFYSQRIHDKCYRRPHFD
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
AGQFVEEWDDESARKGFCLYKMGCKGPTTYNACSTTRWNEGTSFPIQSGHGCIGCSEDGF
HHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
WDKGSFYDRLTGISQFGVEANADKIGGTASVVVGAAVTAHAAASAIKRASKKNETSGSEH
CCCCCHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1383192; 12948488; 2493816