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The map label for this gene is trxB [H]

Identifier: 38234906

GI number: 38234906

Start: 2480310

End: 2481254

Strand: Direct

Name: trxB [H]

Synonym: DIP2373

Alternate gene names: 38234906

Gene position: 2480310-2481254 (Clockwise)

Preceding gene: 38234905

Following gene: 38234907

Centisome position: 99.67

GC content: 55.45

Gene sequence:

>945_bases
ATGACTGACACCACCGCTGGAACAATCCACGACGTTGCCATTATCGGATCAGGCCCAGCCGGCTACACCGCAGCGCTTTA
TGCAGCTCGCGCCGAACTTAAGCCCATTGTGTTCGAGGGCATCGAATACGGTGGTTCGCTGATGACCACCACCGAGGTAG
AAAACTTCCCAGGTTTCCCCGAGGGCATCATGGGCCCTGAGCTCATGCAGAACATGCGCGAGCAGGCCGAGAAGTTCGGT
GCCGAGCTGCGCATGGAGCTGGTGACCAAGGTTGAGCTGGAAGGCGATATAAAAAAGATCTGGGTGGATGATCAGGAGTT
CCAGGCTCGCACTGTCATCTTGGCCACGGGTTCTGCACCGCGTTATCTCGGTGTAGAAGGGGAGCAGACTTTGTTGGGCC
GTGGCGTGTCGGCATGTGCAACCTGTGATGGGTTCTTCTTCCGTGACCACCACATTGCTGTGATTGGTGGCGGCGACTCT
GCAATGGAGGAGGCGGACTTCTTGACCAAGTTCGGCTCTAAGGTGTCGATTGTTCACCGTCGTGATGAGTTCCGTGCGTC
GGCCATTATGTTGGAGCGCGCGAAGAACAATCCAAAAATTGAGTTTGTTACGAATAAAACAGTGTCGAAGGTTTTGGGAG
ATACCACTGTTAGTGGTCTTGAGCTTACTGACACCGTCACCGGCGAGACTTCGGTTCTCGATGCCACCGCCATGTTCGTT
GCTATTGGACACGATCCACGCTCGGCAATGTTCCGCGATGTTGTCACCACCGATGCCGCTGGTTACGTCGTAGTGGAACA
CCCCAGCACCAAGACAAATGTGCCAGGTGTGTTCGCTGTCGGTGACCTCGTGGACAATCACTACCAGCAGGCCATTACTG
CGGCTGGTTCCGGTTGCCGCGGAGCTATCGACGCCGAGCATTACCTGGCAGCACTGAATTCTTAA

Upstream 100 bases:

>100_bases
TATGGAATGAATCCCACCAAGTAGGCGTTGTGCCCATCAAACAGCGACTACTGATTACACTGTGGTCATGTATCAACCGA
CAAAAGGGAGTACCACATCC

Downstream 100 bases:

>100_bases
AGGAGCATTTACTCATGTCAAACGCTATTGCTTTAACCCAGGACACGTTCAAGAGCATTGTTATCGACTCGGATAAGCCG
GTGTTGGTTGATTTTTGGGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTDTTAGTIHDVAIIGSGPAGYTAALYAARAELKPIVFEGIEYGGSLMTTTEVENFPGFPEGIMGPELMQNMREQAEKFG
AELRMELVTKVELEGDIKKIWVDDQEFQARTVILATGSAPRYLGVEGEQTLLGRGVSACATCDGFFFRDHHIAVIGGGDS
AMEEADFLTKFGSKVSIVHRRDEFRASAIMLERAKNNPKIEFVTNKTVSKVLGDTTVSGLELTDTVTGETSVLDATAMFV
AIGHDPRSAMFRDVVTTDAAGYVVVEHPSTKTNVPGVFAVGDLVDNHYQQAITAAGSGCRGAIDAEHYLAALNS

Sequences:

>Translated_314_residues
MTDTTAGTIHDVAIIGSGPAGYTAALYAARAELKPIVFEGIEYGGSLMTTTEVENFPGFPEGIMGPELMQNMREQAEKFG
AELRMELVTKVELEGDIKKIWVDDQEFQARTVILATGSAPRYLGVEGEQTLLGRGVSACATCDGFFFRDHHIAVIGGGDS
AMEEADFLTKFGSKVSIVHRRDEFRASAIMLERAKNNPKIEFVTNKTVSKVLGDTTVSGLELTDTVTGETSVLDATAMFV
AIGHDPRSAMFRDVVTTDAAGYVVVEHPSTKTNVPGVFAVGDLVDNHYQQAITAAGSGCRGAIDAEHYLAALNS
>Mature_313_residues
TDTTAGTIHDVAIIGSGPAGYTAALYAARAELKPIVFEGIEYGGSLMTTTEVENFPGFPEGIMGPELMQNMREQAEKFGA
ELRMELVTKVELEGDIKKIWVDDQEFQARTVILATGSAPRYLGVEGEQTLLGRGVSACATCDGFFFRDHHIAVIGGGDSA
MEEADFLTKFGSKVSIVHRRDEFRASAIMLERAKNNPKIEFVTNKTVSKVLGDTTVSGLELTDTVTGETSVLDATAMFVA
IGHDPRSAMFRDVVTTDAAGYVVVEHPSTKTNVPGVFAVGDLVDNHYQQAITAAGSGCRGAIDAEHYLAALNS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=47.7272727272727, Blast_Score=287, Evalue=6e-79,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=30.0653594771242, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=48.8958990536278, Blast_Score=292, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=45.859872611465, Blast_Score=276, Evalue=4e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33606; Mature: 33475

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTAGTIHDVAIIGSGPAGYTAALYAARAELKPIVFEGIEYGGSLMTTTEVENFPGFP
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEECHHCCCCEEEEEECCCCCCCC
EGIMGPELMQNMREQAEKFGAELRMELVTKVELEGDIKKIWVDDQEFQARTVILATGSAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCEEEEEEEECCCC
RYLGVEGEQTLLGRGVSACATCDGFFFRDHHIAVIGGGDSAMEEADFLTKFGSKVSIVHR
CEECCCCCHHHHHCCCHHHHHCCCEEEECCEEEEEECCCHHHHHHHHHHHCCCEEEEEEE
RDEFRASAIMLERAKNNPKIEFVTNKTVSKVLGDTTVSGLELTDTVTGETSVLDATAMFV
CHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEEEE
AIGHDPRSAMFRDVVTTDAAGYVVVEHPSTKTNVPGVFAVGDLVDNHYQQAITAAGSGCR
EECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCC
GAIDAEHYLAALNS
CCCCHHHHHHCCCC
>Mature Secondary Structure 
TDTTAGTIHDVAIIGSGPAGYTAALYAARAELKPIVFEGIEYGGSLMTTTEVENFPGFP
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEECHHCCCCEEEEEECCCCCCCC
EGIMGPELMQNMREQAEKFGAELRMELVTKVELEGDIKKIWVDDQEFQARTVILATGSAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCEEEEEEEECCCC
RYLGVEGEQTLLGRGVSACATCDGFFFRDHHIAVIGGGDSAMEEADFLTKFGSKVSIVHR
CEECCCCCHHHHHCCCHHHHHCCCEEEECCEEEEEECCCHHHHHHHHHHHCCCEEEEEEE
RDEFRASAIMLERAKNNPKIEFVTNKTVSKVLGDTTVSGLELTDTVTGETSVLDATAMFV
CHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEECCCCCHHEEEEEEEE
AIGHDPRSAMFRDVVTTDAAGYVVVEHPSTKTNVPGVFAVGDLVDNHYQQAITAAGSGCR
EECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCC
GAIDAEHYLAALNS
CCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]