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The map label for this gene is trpD

Identifier: 38234888

GI number: 38234888

Start: 2460247

End: 2461272

Strand: Direct

Name: trpD

Synonym: DIP2354

Alternate gene names: 38234888

Gene position: 2460247-2461272 (Clockwise)

Preceding gene: 38234887

Following gene: 38234889

Centisome position: 98.86

GC content: 60.82

Gene sequence:

>1026_bases
ATGACAAGCGACAAAACACTCAACAACCTCATCGCCTACCTCGACAACCCACACCCCACCGTCGAACAAGCCATTGAAGT
ATTCACACCACTCACCGTCGGCGACTACGACGACGTCCACATCGCAGCGCTGCTCGCCACCATCCGCACCCGCGGCGAAA
CCTACGCCGACATCGCCGGCGCCGCCAAAGCATTCCTCGCCGCCGGACGACCATTTCCCATCACCGGCGCAGGTCTCATG
GACTCCGCAGGAACCGGCGGCGATGGTGCCAATACCATTAACGTGACCACCGCGGCGTCCCTTGTCGCCGCCGCTGGGGG
AGTGAAGATGGTCAAATGTGGCAACCGATCCGTATCCTCCAAATCCGGATCCGCCGACGTACTCGAAGCACTCAACATCC
CACTAGACCTCAACCCCGACCGCGCCGTGCGCCAATTCAACGCCTCCAATTTCACGTTCCTTTTTGCGCCCGCCTACAAC
CCCGCGGTCGCCCACGTGCAACCAGTGCGCAAGGCCCTCAAAGTGCCCACGCTGTTTAACACCCTCGGCCCGATCTTGGC
GCCGGCTCGCCCCGAATTTCAGGTCATGGGCGTTGCCAACCCCAAGCTCGGTCAGATTATCGCCGAGGTGTTCCGCGAAC
TAGGTCGCAGCCACGCCTTGGTTGTTCACGGATCCGGCACCGACGAGATCGCAGTCCATGGCCCCACCACGGTATGGGAA
CTTCGCGATGGTGAGATCAGCACCTACACCATCACACCAGAAGAAATCGGTATCAACCGCTACGAGTTGAGCGAGCTCGC
AGGTGGCGACGGCGTAGAAAACGCACACCTCATGCGCGAAACCTTCGCCAGCCGTGGTCCCGCCGCACACCGCGACGCTA
TTAGCGCCACCGCCGGCGCAATGTTCTACACTGCGAATCACGTACCCACCATCGCCGAGGGAGTCGCTAAGGCACAAACA
ATGCTTGCCGACGGCTCCGTGGAGCGCTGGTTAGCTATCCACGAGGAGGCAAACTATGCAGAATGA

Upstream 100 bases:

>100_bases
TGCAATTCCACCCCGAATCCGTACTAAGCCCCAGCGGGCCCATCATCCTTGAACGATGCGTCGATAAGCTGCTAGCCAAC
AAATAAGAAAGACCACAACC

Downstream 100 bases:

>100_bases
TTCGTCGACACGCCCCATGCCCACCGTCCTAGAATCCATCGTTTCGGGCCGACGATCCCACCTGCCCGAAATCCAAGCGC
GGATTTCCCACGTGGACCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTSDKTLNNLIAYLDNPHPTVEQAIEVFTPLTVGDYDDVHIAALLATIRTRGETYADIAGAAKAFLAAGRPFPITGAGLM
DSAGTGGDGANTINVTTAASLVAAAGGVKMVKCGNRSVSSKSGSADVLEALNIPLDLNPDRAVRQFNASNFTFLFAPAYN
PAVAHVQPVRKALKVPTLFNTLGPILAPARPEFQVMGVANPKLGQIIAEVFRELGRSHALVVHGSGTDEIAVHGPTTVWE
LRDGEISTYTITPEEIGINRYELSELAGGDGVENAHLMRETFASRGPAAHRDAISATAGAMFYTANHVPTIAEGVAKAQT
MLADGSVERWLAIHEEANYAE

Sequences:

>Translated_341_residues
MTSDKTLNNLIAYLDNPHPTVEQAIEVFTPLTVGDYDDVHIAALLATIRTRGETYADIAGAAKAFLAAGRPFPITGAGLM
DSAGTGGDGANTINVTTAASLVAAAGGVKMVKCGNRSVSSKSGSADVLEALNIPLDLNPDRAVRQFNASNFTFLFAPAYN
PAVAHVQPVRKALKVPTLFNTLGPILAPARPEFQVMGVANPKLGQIIAEVFRELGRSHALVVHGSGTDEIAVHGPTTVWE
LRDGEISTYTITPEEIGINRYELSELAGGDGVENAHLMRETFASRGPAAHRDAISATAGAMFYTANHVPTIAEGVAKAQT
MLADGSVERWLAIHEEANYAE
>Mature_340_residues
TSDKTLNNLIAYLDNPHPTVEQAIEVFTPLTVGDYDDVHIAALLATIRTRGETYADIAGAAKAFLAAGRPFPITGAGLMD
SAGTGGDGANTINVTTAASLVAAAGGVKMVKCGNRSVSSKSGSADVLEALNIPLDLNPDRAVRQFNASNFTFLFAPAYNP
AVAHVQPVRKALKVPTLFNTLGPILAPARPEFQVMGVANPKLGQIIAEVFRELGRSHALVVHGSGTDEIAVHGPTTVWEL
RDGEISTYTITPEEIGINRYELSELAGGDGVENAHLMRETFASRGPAAHRDAISATAGAMFYTANHVPTIAEGVAKAQTM
LADGSVERWLAIHEEANYAE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=265, Percent_Identity=44.1509433962264, Blast_Score=211, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6320561, Length=281, Percent_Identity=30.9608540925267, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_CORDI (Q6NEC1)

Other databases:

- EMBL:   BX248361
- RefSeq:   NP_940655.1
- ProteinModelPortal:   Q6NEC1
- SMR:   Q6NEC1
- GeneID:   2649177
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP2354
- NMPDR:   fig|257309.1.peg.2246
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q6NEC1
- ProtClustDB:   PRK00188
- BioCyc:   CDIP257309:DIP2354-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35928; Mature: 35797

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDKTLNNLIAYLDNPHPTVEQAIEVFTPLTVGDYDDVHIAALLATIRTRGETYADIAG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
AAKAFLAAGRPFPITGAGLMDSAGTGGDGANTINVTTAASLVAAAGGVKMVKCGNRSVSS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCC
KSGSADVLEALNIPLDLNPDRAVRQFNASNFTFLFAPAYNPAVAHVQPVRKALKVPTLFN
CCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHH
TLGPILAPARPEFQVMGVANPKLGQIIAEVFRELGRSHALVVHGSGTDEIAVHGPTTVWE
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEE
LRDGEISTYTITPEEIGINRYELSELAGGDGVENAHLMRETFASRGPAAHRDAISATAGA
EECCCEEEEEECHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCE
MFYTANHVPTIAEGVAKAQTMLADGSVERWLAIHEEANYAE
EEEECCCCCHHHHHHHHHHHHHCCCCHHHHEEECCCCCCCC
>Mature Secondary Structure 
TSDKTLNNLIAYLDNPHPTVEQAIEVFTPLTVGDYDDVHIAALLATIRTRGETYADIAG
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
AAKAFLAAGRPFPITGAGLMDSAGTGGDGANTINVTTAASLVAAAGGVKMVKCGNRSVSS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCC
KSGSADVLEALNIPLDLNPDRAVRQFNASNFTFLFAPAYNPAVAHVQPVRKALKVPTLFN
CCCCHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHH
TLGPILAPARPEFQVMGVANPKLGQIIAEVFRELGRSHALVVHGSGTDEIAVHGPTTVWE
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCEEEE
LRDGEISTYTITPEEIGINRYELSELAGGDGVENAHLMRETFASRGPAAHRDAISATAGA
EECCCEEEEEECHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCE
MFYTANHVPTIAEGVAKAQTMLADGSVERWLAIHEEANYAE
EEEECCCCCHHHHHHHHHHHHHCCCCHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910