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The map label for this gene is chrS [H]

Identifier: 38234860

GI number: 38234860

Start: 2430452

End: 2431705

Strand: Direct

Name: chrS [H]

Synonym: DIP2326

Alternate gene names: 38234860

Gene position: 2430452-2431705 (Clockwise)

Preceding gene: 38234840

Following gene: 38234861

Centisome position: 97.66

GC content: 55.98

Gene sequence:

>1254_bases
ATGCTCGCTAGTGTGAAGCCTCATGTGATTCAAATTCTCACCGTCATGCGTGTCAGCCTGCATGTAATGTTCGCTGGTCT
GCTCATTTTTGGAATCGTACGTTATTATCTCGAGCTTCCAACAGTTCCAACCGATGCAAACAATATTGCTATCGCCGCAG
CAATCACGCTGGGAATTTTCTACATGATCGGCACCGCATGGGAAAATCGTTTCGCGCGTGGCGACGACATCCCGGACCCC
GGGATACTCAGTCCCGTGTGGCTCGTGATTATTGTTGCTCTCTGGGCTTTCCTCGTAGGTGCCTCCGGCTATTTCCTGTG
GCTGATGTTCCCACTCGTATTTGTAATGTTGCATCTCAAGCAGGGCATTCGTGGCATCTTGGGCGTTGCCTTACTCCTTG
CCATCGCCATCGCAATTCCCCTAGCCACACGCCCAGATGAGTGGATGCCCGCACAGGCCATGGGCCCAACGATGGGTGCC
GCGTTTTCCACGGTGATTTTTTATAGCTACACCACCTTGCGCAACGATGCCCAACATTACCGCCAACTAGCGGCAGAGTT
GCTTGCAGCCCAGCAGGATCTCGCCACCTCTGAACATCAGGCAGGCCGGCTCGAGGAGCGCGAGCGGCTCTCTCGCGAGA
TCCATGACACAGTTGCCCAAGGATTGAGTTCCATCGTAATCTTGGCACGCGCCGCACACGGCCGCCTCGATAAAGGTGAA
ATTGAAGATGTGGCACAGCAACTCAGCGTGATCGAAACCCAAGCCTCTGACAGCCTTGCAGAGGCACGCCGCTTTGTGCG
CGACCTAGCAGCCCCAGCACTGGGCGACTCGCTGCCTATCGCACTGACCAGTACCATTAATAATCTACGCACCAAACAGG
ATGCTCTCGGTGCGCCATTGGATGTTCATTTAGAGCTCGTGGGGGATACGTCGATAAGCCTGCCGGAGCCGGTATCGCGC
ACGGTGGTTCGCGTGACCCAAGAAGGGCTCAACAATGTGGTTAAACATGCTCATGCCACAAAAGCGGTGGTCACATTGGG
CGTGTGGGAGGACGAGGTCAGCCTCGACGTGGTGGACAATGGGATCGGGTTCAACCTCGGTACCACCGAGCGTGGCACCA
GCTCCGGCTTTGGCCTTGATGGCCTTCGCAAGCGCGTAGATACCGTTGGTGGCACACTCGTGATTGAATCAGATACATAC
GGCACCGCACTCGCTTGCCGCATTCCGCTTACCAGCCGCCGGGAGACTTCATGA

Upstream 100 bases:

>100_bases
TATTTTCATTAAAAGGTATAGCCTAATTTGCTCCTATGCAACATAGGCTTCAATTAAGCGAACTTTCCTTCCAATCCATC
ACAGGCGCAGGAGATCTTTT

Downstream 100 bases:

>100_bases
TCCGCGTCATGCTTATCGACGACCACCCCGTAGTCCGCGCCGGACTGCGCTCCATTTTGGACAGCTTCGATGACATCACC
GTGGTCGCCGAAGCCAGCGA

Product: two-component system histidine kinase ChrS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLASVKPHVIQILTVMRVSLHVMFAGLLIFGIVRYYLELPTVPTDANNIAIAAAITLGIFYMIGTAWENRFARGDDIPDP
GILSPVWLVIIVALWAFLVGASGYFLWLMFPLVFVMLHLKQGIRGILGVALLLAIAIAIPLATRPDEWMPAQAMGPTMGA
AFSTVIFYSYTTLRNDAQHYRQLAAELLAAQQDLATSEHQAGRLEERERLSREIHDTVAQGLSSIVILARAAHGRLDKGE
IEDVAQQLSVIETQASDSLAEARRFVRDLAAPALGDSLPIALTSTINNLRTKQDALGAPLDVHLELVGDTSISLPEPVSR
TVVRVTQEGLNNVVKHAHATKAVVTLGVWEDEVSLDVVDNGIGFNLGTTERGTSSGFGLDGLRKRVDTVGGTLVIESDTY
GTALACRIPLTSRRETS

Sequences:

>Translated_417_residues
MLASVKPHVIQILTVMRVSLHVMFAGLLIFGIVRYYLELPTVPTDANNIAIAAAITLGIFYMIGTAWENRFARGDDIPDP
GILSPVWLVIIVALWAFLVGASGYFLWLMFPLVFVMLHLKQGIRGILGVALLLAIAIAIPLATRPDEWMPAQAMGPTMGA
AFSTVIFYSYTTLRNDAQHYRQLAAELLAAQQDLATSEHQAGRLEERERLSREIHDTVAQGLSSIVILARAAHGRLDKGE
IEDVAQQLSVIETQASDSLAEARRFVRDLAAPALGDSLPIALTSTINNLRTKQDALGAPLDVHLELVGDTSISLPEPVSR
TVVRVTQEGLNNVVKHAHATKAVVTLGVWEDEVSLDVVDNGIGFNLGTTERGTSSGFGLDGLRKRVDTVGGTLVIESDTY
GTALACRIPLTSRRETS
>Mature_417_residues
MLASVKPHVIQILTVMRVSLHVMFAGLLIFGIVRYYLELPTVPTDANNIAIAAAITLGIFYMIGTAWENRFARGDDIPDP
GILSPVWLVIIVALWAFLVGASGYFLWLMFPLVFVMLHLKQGIRGILGVALLLAIAIAIPLATRPDEWMPAQAMGPTMGA
AFSTVIFYSYTTLRNDAQHYRQLAAELLAAQQDLATSEHQAGRLEERERLSREIHDTVAQGLSSIVILARAAHGRLDKGE
IEDVAQQLSVIETQASDSLAEARRFVRDLAAPALGDSLPIALTSTINNLRTKQDALGAPLDVHLELVGDTSISLPEPVSR
TVVRVTQEGLNNVVKHAHATKAVVTLGVWEDEVSLDVVDNGIGFNLGTTERGTSSGFGLDGLRKRVDTVGGTLVIESDTY
GTALACRIPLTSRRETS

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=241, Percent_Identity=34.8547717842324, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45147; Mature: 45147

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]