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The map label for this gene is hsdM [C]

Identifier: 38234849

GI number: 38234849

Start: 2413807

End: 2415414

Strand: Reverse

Name: hsdM [C]

Synonym: DIP2314

Alternate gene names: 38234849

Gene position: 2415414-2413807 (Counterclockwise)

Preceding gene: 38234850

Following gene: 38234848

Centisome position: 97.06

GC content: 53.98

Gene sequence:

>1608_bases
ATGGTACGGAAGAAGAAGGAAGTGGCGCAGGTCCCTTCCACCTCTAAGGAAATCAAGGACACATTGTGGAAGTCCGCGGA
TAAGCTTCGCGGTTCTATGGATGCGTCGCAGTACAAGGATGTTGCTCTGGGGCTGGTGTTCCTAAAGTATGTATCGGATT
CCTTTGAGGAACGTCAGAAGGAAATCCGCGCGGAGCTAGAAGGCAAGGGCTTCGATGAGGAATACATCCTAGAAGATCTT
GCCGACGTTGACGCTTACACCAGCGAGAATGTTTTTTGGGTGGCGTCGAATGCCCGTTGGGACTTCCTAAAGAAGTATTC
CAAGGGCATGGATCTGGAAGGAAAACACAAGTCTATCGGCAAGTTGATCGATGAGGCTATGCAGCAGCTCATGGCGGATA
ACGAATCGCTACTGGGCACGCTGCCGCAGATTTATGGCAAGGACAATATCGACCAGCGCCGTCTCGGTGAATTAGTGGAC
CTGTTTAGCTCTACGTATTTTGCCAGCACTAAGGATAAGAAGGCCCGCGACCTGCTTGGGGAGGTTTACGAGTACTTTCT
GGATAAGTTCGCCAAGGCCGAGGGTAAGAGGGGTGGCGAGTTTTATACGCCGCAGCCGGTCGTGCGGACGTTGGTAGAAA
TCCTTGAGCCGACTGAGGGGCGTGTGTATGACCCATGCTGTGGTTCGGGTGGCATGTTTGTGCAGGCGGAAAAGTTCTTG
GAGGTTACCAAGCGTGACCGCAGCAACATTGCGGTTTATGGCCAAGAACTCAATGAGCGTACTTGGCGAATGGCGAAGAT
GAACTTGGCTATTCACGCCATCAGTTCGTCCGGTTTGGGTGAGCGTTGGGGTGACACGTTTGCTCGCGATATTCATGCGG
GCACCAAGATGGATTACATCATGGCTAATCCGCCGTTCAACATTAAGGATTGGATCCGCAATGAGGAGGATGCCCGTTGG
AAGTACGGTGTGCCTCCGGCGAAGAATGCGAACTTTGCGTGGATACAGCACATCATTTCGAAGCTGAAGGATCACGGCGA
AGCTGGTGTTGTGATGGCGAATGGCACCATGACGTCGCAAAGCTCTGGTGAGGGCGAGATCCGTAAGAACATGGTGGAAG
ATGATGTTGTTTCGTGTGTGATTGCGTTGCCGGCGCAGTTGTTCCGTGGCACGGGCATTCCGGTGTGCGTGTGGTTTTTT
GCTAAGGATAAGTCGGCGGGTGTTGGTGGCAGTGTTGATCGCCGTGGTGAGGTGTTGCTTATCGACGCCCGCCAGCTCGG
CCACATGATCGACCGCACGGAGCGGGCGTTTAGTGATGAGGACATCACCAAGATTGCTAATGCGTTCCGAACCTGGCGTG
GGCGTAAGTCCGCGGAGGGAGAGTACGAGGACGAGGCGGGATTCTGTAAGTCCGCCACAATTGAGGAGATCCGCGAAGCT
GGCTACGCGCTAACACCTGGCCGCTATGTGGGCATGCCTGAGGCCGAAGAAGATGATGAGCCTATCGACGAAAAGATTGC
ACGTCTAACCGCAGAACTGACTGCTGCATTGGACGAGTCTGCACGTTTGGACGCTGTCGTCCGCGAACAGCTGGGGAGGT
TGAAGTGA

Upstream 100 bases:

>100_bases
TTAGGGCGGCGCCTGGTTAGCTCACGCGATAACTGCATGAAGCTCAGTGCTTCAACGAAACTAGAAAATAGCGAAAAGCA
AAGAGAAGTGAGGAAAGAAA

Downstream 100 bases:

>100_bases
GAATACAGATTGGTGAGCTCATTCGTTCAGGTGTCCTTGAACTGGGTGATGGTTACCGTACTAAGAGGTCTGAACTCTCC
CAATTTGGCTATGCCATTGT

Product: putative type I restriction/modification system DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQKEIRAELEGKGFDEEYILEDL
ADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVD
LFSSTYFASTKDKKARDLLGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYIMANPPFNIKDWIRNEEDARW
KYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFF
AKDKSAGVGGSVDRRGEVLLIDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK

Sequences:

>Translated_535_residues
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQKEIRAELEGKGFDEEYILEDL
ADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVD
LFSSTYFASTKDKKARDLLGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYIMANPPFNIKDWIRNEEDARW
KYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFF
AKDKSAGVGGSVDRRGEVLLIDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK
>Mature_535_residues
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQKEIRAELEGKGFDEEYILEDL
ADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVD
LFSSTYFASTKDKKARDLLGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYIMANPPFNIKDWIRNEEDARW
KYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFF
AKDKSAGVGGSVDRRGEVLLIDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=427, Percent_Identity=24.824355971897, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 60208; Mature: 60208

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQK
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRAELEGKGFDEEYILEDLADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIG
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHH
KLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVDLFSSTYFASTKDKKARDLLG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
EVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEHHHHH
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYI
HHHHCCCCCEEEECHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
MANPPFNIKDWIRNEEDARWKYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQ
EECCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCC
SSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFFAKDKSAGVGGSVDRRGEVLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
IDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
EEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK
CCEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQK
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRAELEGKGFDEEYILEDLADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIG
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHH
KLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVDLFSSTYFASTKDKKARDLLG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
EVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEHHHHH
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYI
HHHHCCCCCEEEECHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCEE
MANPPFNIKDWIRNEEDARWKYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQ
EECCCCCHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCC
SSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFFAKDKSAGVGGSVDRRGEVLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
IDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
EEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK
CCEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]