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The map label for this gene is acm [H]

Identifier: 38234841

GI number: 38234841

Start: 2402330

End: 2403466

Strand: Reverse

Name: acm [H]

Synonym: DIP2306

Alternate gene names: 38234841

Gene position: 2403466-2402330 (Counterclockwise)

Preceding gene: 38234842

Following gene: 38234838

Centisome position: 96.58

GC content: 59.37

Gene sequence:

>1137_bases
TTGTGTATTGTGCGGGGCGTGAAGAAAAAGAGCCATTTGCTATCCGGAATTACCGGCGGAACTGTTGCAGTGCTGACGTC
CGCGATGCTGGCCATCGCACCCGCGCACGCCCTTCCGTTGCCCATCCCCATCGGAGCGTCCTCGGGTATCGACGTCTCCG
GCCACCAACACCCAGGCGGAATCGCCATCGACTGGAAGAGCGTCCAACGTGACGGTCAAAGCTTCGCATTCGTCAAAGCC
TCCGAAGGTGAAGGCTGGAGCAACGACTACTTCACCCAAGACGCCAAACAGGCAGCCAACAGTGGCCTCAAAGTAGGCAC
CTACCACTACGCGCGTCCCTCCAAAGACGCCCGCACCCAAGCACGCCACTACGCAGCGCAGGTCGCCCAAATCAACGACC
ACTCCCTGCCACCCGTACTCGACATCGAGGTCGCAGAAGGCAAAACCCCAGAACAGCTCGCAGCCTGGACCAAAACATTC
CTCAACGAATTTGAGTCCCAATCCGGCCGCAAGCCAATGATCTACACCTACCGCTACTTCTGGACCCACGACATGGCCAA
CACCAAGCAGTTCGCGGAATACCCACTCTGGCTGGCGGCCTACCAAACCCAAGCCCCAGAACCAGTTGGCGGTTGGGACA
CCATCGACTTCTGGCAGCGCTCCGGAAGCGGACGCATTAATGGCATCGTCGGCGACGTAGACCTCAACCTCTTCAACGGT
GACGACGCACAACTCGACGCCTTCGCGGCGGGCAACTACGCCTCCGCCGGCGGCAAGTTTGCATCCATCTCACTCCCCGG
TATCGCAGACCTCGGCGGCGACTCTCAGGCTCTTGTCAGTGCTGTTGCAGCGCTGGCAGCCGGCGTAGCCGCAGCGCCAC
AGGTAGCACAAGCAGCTGAAAACGCAGGCTTGAGCACCGAAGGAGCAGAAGAACTGATCAAGGTCGTCCAAGACCTCATC
AACTCCGGCAACCTCCCCATCGACCAGCTCAAAGACCTCGCAGCCGGAAACTACTCGGTGGGTGACCTCGTGATCCTGCT
CGACAACGCCCAGCACCTTGCTGCCACATCAAGCGAGCCACAAAACCAGAACATCAACGTCGATCAGCTCGTCGCCTTGG
CGAAGAACTTTATCTAA

Upstream 100 bases:

>100_bases
TGGTGGCGTTGGCGGTGTTTGGAATGAGTGCGGGCGCTTGACTATGTGGTGACATAAGTTGTTGAAGTTGGGCGTGTTGC
TCCTGTGACTTGTGTGAAAG

Downstream 100 bases:

>100_bases
ATAAAGTTTCTGTTAGCGCAGTTTTTTGCCCTGCGATAACAACGCCGTGGCCTGGGGGATCGTGTTGGCAATGCGCAATG
CGGACGTAGGGGCGAGTCCG

Product: putative hydrolase

Products: NA

Alternate protein names: 1,4-beta-N-acetylmuramidase M1 [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MCIVRGVKKKSHLLSGITGGTVAVLTSAMLAIAPAHALPLPIPIGASSGIDVSGHQHPGGIAIDWKSVQRDGQSFAFVKA
SEGEGWSNDYFTQDAKQAANSGLKVGTYHYARPSKDARTQARHYAAQVAQINDHSLPPVLDIEVAEGKTPEQLAAWTKTF
LNEFESQSGRKPMIYTYRYFWTHDMANTKQFAEYPLWLAAYQTQAPEPVGGWDTIDFWQRSGSGRINGIVGDVDLNLFNG
DDAQLDAFAAGNYASAGGKFASISLPGIADLGGDSQALVSAVAALAAGVAAAPQVAQAAENAGLSTEGAEELIKVVQDLI
NSGNLPIDQLKDLAAGNYSVGDLVILLDNAQHLAATSSEPQNQNINVDQLVALAKNFI

Sequences:

>Translated_378_residues
MCIVRGVKKKSHLLSGITGGTVAVLTSAMLAIAPAHALPLPIPIGASSGIDVSGHQHPGGIAIDWKSVQRDGQSFAFVKA
SEGEGWSNDYFTQDAKQAANSGLKVGTYHYARPSKDARTQARHYAAQVAQINDHSLPPVLDIEVAEGKTPEQLAAWTKTF
LNEFESQSGRKPMIYTYRYFWTHDMANTKQFAEYPLWLAAYQTQAPEPVGGWDTIDFWQRSGSGRINGIVGDVDLNLFNG
DDAQLDAFAAGNYASAGGKFASISLPGIADLGGDSQALVSAVAALAAGVAAAPQVAQAAENAGLSTEGAEELIKVVQDLI
NSGNLPIDQLKDLAAGNYSVGDLVILLDNAQHLAATSSEPQNQNINVDQLVALAKNFI
>Mature_378_residues
MCIVRGVKKKSHLLSGITGGTVAVLTSAMLAIAPAHALPLPIPIGASSGIDVSGHQHPGGIAIDWKSVQRDGQSFAFVKA
SEGEGWSNDYFTQDAKQAANSGLKVGTYHYARPSKDARTQARHYAAQVAQINDHSLPPVLDIEVAEGKTPEQLAAWTKTF
LNEFESQSGRKPMIYTYRYFWTHDMANTKQFAEYPLWLAAYQTQAPEPVGGWDTIDFWQRSGSGRINGIVGDVDLNLFNG
DDAQLDAFAAGNYASAGGKFASISLPGIADLGGDSQALVSAVAALAAGVAAAPQVAQAAENAGLSTEGAEELIKVVQDLI
NSGNLPIDQLKDLAAGNYSVGDLVILLDNAQHLAATSSEPQNQNINVDQLVALAKNFI

Specific function: This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities [H]

COG id: COG3757

COG function: function code M; Lyzozyme M1 (1,4-beta-N-acetylmuramidase)

Gene ontology:

Cell location: Secreted, extracellular space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 25 family [H]

Homologues:

Organism=Escherichia coli, GI87082043, Length=225, Percent_Identity=36, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002053
- InterPro:   IPR008270
- InterPro:   IPR017853
- InterPro:   IPR018077
- InterPro:   IPR013781 [H]

Pfam domain/function: PF01183 Glyco_hydro_25 [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 39987; Mature: 39987

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIVRGVKKKSHLLSGITGGTVAVLTSAMLAIAPAHALPLPIPIGASSGIDVSGHQHPGG
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
IAIDWKSVQRDGQSFAFVKASEGEGWSNDYFTQDAKQAANSGLKVGTYHYARPSKDARTQ
EEEEHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHH
ARHYAAQVAQINDHSLPPVLDIEVAEGKTPEQLAAWTKTFLNEFESQSGRKPMIYTYRYF
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
WTHDMANTKQFAEYPLWLAAYQTQAPEPVGGWDTIDFWQRSGSGRINGIVGDVDLNLFNG
EECCCCCHHHHHHCCEEEEEHHCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEEEECC
DDAQLDAFAAGNYASAGGKFASISLPGIADLGGDSQALVSAVAALAAGVAAAPQVAQAAE
CCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
NAGLSTEGAEELIKVVQDLINSGNLPIDQLKDLAAGNYSVGDLVILLDNAQHLAATSSEP
HCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCC
QNQNINVDQLVALAKNFI
CCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MCIVRGVKKKSHLLSGITGGTVAVLTSAMLAIAPAHALPLPIPIGASSGIDVSGHQHPGG
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
IAIDWKSVQRDGQSFAFVKASEGEGWSNDYFTQDAKQAANSGLKVGTYHYARPSKDARTQ
EEEEHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHH
ARHYAAQVAQINDHSLPPVLDIEVAEGKTPEQLAAWTKTFLNEFESQSGRKPMIYTYRYF
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
WTHDMANTKQFAEYPLWLAAYQTQAPEPVGGWDTIDFWQRSGSGRINGIVGDVDLNLFNG
EECCCCCHHHHHHCCEEEEEHHCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEEEECC
DDAQLDAFAAGNYASAGGKFASISLPGIADLGGDSQALVSAVAALAAGVAAAPQVAQAAE
CCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
NAGLSTEGAEELIKVVQDLINSGNLPIDQLKDLAAGNYSVGDLVILLDNAQHLAATSSEP
HCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCC
QNQNINVDQLVALAKNFI
CCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2341041 [H]