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The map label for this gene is oxaA [H]

Identifier: 38234809

GI number: 38234809

Start: 2364341

End: 2365648

Strand: Direct

Name: oxaA [H]

Synonym: DIP2273

Alternate gene names: 38234809

Gene position: 2364341-2365648 (Clockwise)

Preceding gene: 38234806

Following gene: 38234813

Centisome position: 95.01

GC content: 55.5

Gene sequence:

>1308_bases
GTGCTTGAGATGTTTATCTATCCCGTATCCGGTGTGATGCGGCTGTGGCACTACATTTTTGCGGATCTATTTGGCTGCTC
CCAGTCACAGGCCTGGGTAGCGTCGCTATTCGCCCTTGTGGTCACAGTCCGATCCATCATTGCTCCCTTCTCGTGGATGC
AGTTTAAGTCCGGACGCTTCGCTATCATGATGCGCCCCAAGATCAAGCGTCTCAAAGAGGAATACGCCGAGCGCACCGAC
AAGGAGTCCATCCTTGAGCAGGAGCGTCGCCAAAAAGAAATCCAAGAGGAATACGGCTACAGCATGGCCGCGGGCTGCGT
TCCCGCACTGATCCAAGTGCCCGTGTTCTTGGGCCTCTACCAAGTGCTGTTGCGCATGGCCCGCCCCAAAGAGGGCCTCG
ACGCCACCGTTCACGAACCAATCGGCATGCTCACCTCCGACAACGTACGCTCCTTCTTGGACACCCGCTTCTTCGGCGTG
CCGCTGCCCGCCTACAACTCCATGTCCCCAGAGCAGCTCGCACACCTTGGTACCGACCAGCCCACCATCCACGCGTTTGT
TCTGCCGCTTATCATCGCCGCCTGCGTGTTCACCACGATCAACATGATCGTCTCCACCCTGCGCACCCGCTACTCCATCG
ACCACGACTCCGAATTTGCGGTGGGTATGTACCGCTTCCTCATCGTCATGGTGCTCGTCGCCCCCATCGGTTTGCTCCAG
ACTGGCATATTTGGCCCAATCCCTGCCGCTATCTGCTTGTACTGGGTTGCCAACAACTTGTGGACCCTCATTCAAAACAA
CGGCATGTTCCTCGCCCTATGGTGGAAATACCCTTACGACAGCGACCACAAGGCCTTCCAAGCCGAGCGCCGCGCCCAGC
GCGCAGAACGCATAGTGGTAAAAAAGTCCCGCAAAAAAGCGTTACGACGCCTCCGCAACCGCAGCCTCATCCAACCATGG
AAGATTGCGGAACTACGCCAGCAAGCCCGCGACATTAAAAACGAAGTCCGCGAAGAAAAAGAAGCCGAAAAAGCCCGCAA
GAAGGCCATCCGCGAGAAACGTCGTGAAGCCGAAAACGAAATCAACGACGAAAAAAATGCCGAACGCATCGAAAAAATCG
CCCGCCGCGTAGCAAAATACAAAAAGAAAAAGGCCGCTAAGAAGGGCCTTGATCCTAAATCGAATAATCAGCAGGAGGAG
CAGACAGCAACTGAACCGCAAGATCCCGAGCAGTCTTCAACGACTCCACCGAGCGATTCAGACGACAACCCGCAAGACCA
CCATCCAGAAAAACCATCAACTGATTAG

Upstream 100 bases:

>100_bases
CCCACAATCGTAGCGCAGCCCGCCGTTTCCCCTCTACAACCCGATTGCGCGTACCATTTAAGTCTGTTTGTTCGTGATAC
GTCCCGATCGGAGTTTCCCC

Downstream 100 bases:

>100_bases
CCTGAACAGTGCCGGGATACCCGTTCTTCTCCGTCAACAACTGAGTTAACGTCTCCAAACACCACCGGCGATGTTCCATC
ACAACCGACACGATCTCGCG

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLEMFIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRFAIMMRPKIKRLKEEYAERTD
KESILEQERRQKEIQEEYGYSMAAGCVPALIQVPVFLGLYQVLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGV
PLPAYNSMSPEQLAHLGTDQPTIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQ
TGIFGPIPAAICLYWVANNLWTLIQNNGMFLALWWKYPYDSDHKAFQAERRAQRAERIVVKKSRKKALRRLRNRSLIQPW
KIAELRQQARDIKNEVREEKEAEKARKKAIREKRREAENEINDEKNAERIEKIARRVAKYKKKKAAKKGLDPKSNNQQEE
QTATEPQDPEQSSTTPPSDSDDNPQDHHPEKPSTD

Sequences:

>Translated_435_residues
MLEMFIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRFAIMMRPKIKRLKEEYAERTD
KESILEQERRQKEIQEEYGYSMAAGCVPALIQVPVFLGLYQVLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGV
PLPAYNSMSPEQLAHLGTDQPTIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQ
TGIFGPIPAAICLYWVANNLWTLIQNNGMFLALWWKYPYDSDHKAFQAERRAQRAERIVVKKSRKKALRRLRNRSLIQPW
KIAELRQQARDIKNEVREEKEAEKARKKAIREKRREAENEINDEKNAERIEKIARRVAKYKKKKAAKKGLDPKSNNQQEE
QTATEPQDPEQSSTTPPSDSDDNPQDHHPEKPSTD
>Mature_435_residues
MLEMFIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRFAIMMRPKIKRLKEEYAERTD
KESILEQERRQKEIQEEYGYSMAAGCVPALIQVPVFLGLYQVLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGV
PLPAYNSMSPEQLAHLGTDQPTIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQ
TGIFGPIPAAICLYWVANNLWTLIQNNGMFLALWWKYPYDSDHKAFQAERRAQRAERIVVKKSRKKALRRLRNRSLIQPW
KIAELRQQARDIKNEVREEKEAEKARKKAIREKRREAENEINDEKNAERIEKIARRVAKYKKKKAAKKGLDPKSNNQQEE
QTATEPQDPEQSSTTPPSDSDDNPQDHHPEKPSTD

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 50159; Mature: 50159

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEMFIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRF
CCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
AIMMRPKIKRLKEEYAERTDKESILEQERRQKEIQEEYGYSMAAGCVPALIQVPVFLGLY
EEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QVLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGVPLPAYNSMSPEQLAHLGTDQ
HHHHHHHCCCCCCCCHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
PTIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGIFGPIPAAICLYWVANNLWTLIQNNGMFLALWWKYPYDSDHKAFQAERRAQRAERIVV
HCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
KKSRKKALRRLRNRSLIQPWKIAELRQQARDIKNEVREEKEAEKARKKAIREKRREAENE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDEKNAERIEKIARRVAKYKKKKAAKKGLDPKSNNQQEEQTATEPQDPEQSSTTPPSDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
DDNPQDHHPEKPSTD
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MLEMFIYPVSGVMRLWHYIFADLFGCSQSQAWVASLFALVVTVRSIIAPFSWMQFKSGRF
CCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
AIMMRPKIKRLKEEYAERTDKESILEQERRQKEIQEEYGYSMAAGCVPALIQVPVFLGLY
EEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QVLLRMARPKEGLDATVHEPIGMLTSDNVRSFLDTRFFGVPLPAYNSMSPEQLAHLGTDQ
HHHHHHHCCCCCCCCHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
PTIHAFVLPLIIAACVFTTINMIVSTLRTRYSIDHDSEFAVGMYRFLIVMVLVAPIGLLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGIFGPIPAAICLYWVANNLWTLIQNNGMFLALWWKYPYDSDHKAFQAERRAQRAERIVV
HCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
KKSRKKALRRLRNRSLIQPWKIAELRQQARDIKNEVREEKEAEKARKKAIREKRREAENE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDEKNAERIEKIARRVAKYKKKKAAKKGLDPKSNNQQEEQTATEPQDPEQSSTTPPSDS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
DDNPQDHHPEKPSTD
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]