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The map label for this gene is 38234799

Identifier: 38234799

GI number: 38234799

Start: 2354873

End: 2356225

Strand: Reverse

Name: 38234799

Synonym: DIP2263

Alternate gene names: NA

Gene position: 2356225-2354873 (Counterclockwise)

Preceding gene: 38234800

Following gene: 38234796

Centisome position: 94.68

GC content: 58.46

Gene sequence:

>1353_bases
GTGATGAATAACTGCGACGAGCACAGCTTGCTGCGCTTCCTCCGCTGGCGTGGCACCATGGTGGTGGCTTGGCTGGTCCT
TGCGACGATCCTTGTTCTAGGTGTGATGGATCATGACGCTCTTTTTATGCGTAAACCCATCTATGGCTTCGACTCGCTAT
TTATTTATCACTACGACTTCGGCGTGTACTTCGAGGGGGCGAAGGCCTTTGCCGAGCACAAAAACCTCTATACGCAGGGC
TACCAAGTCCACAACATCAGTCTGCCGTTTACTTATCCGCCATTTGCGGCGCTGGCGTTCGTGCCGTTTACGATCCTACC
GGTGCGCGTGGCCGCCCTTCTTTTCGACCTCGGCTCCGTGGTTGCCTTGTGGTGGTGCAGCGTCCTAGTTACGCGGGCTA
TCGTAGGTCAGCGCCCTGCATGGACGCGTATCGACGCCTACCGCCTTGGGCTCGTGGTTACCGCAGCCGCCGCAGTGCTG
GAGCCCATGCGCGAAAATATCTGGTTCGCCCAGATCAACGTCTACCTCATCTTGCTGGTGCTGATCGATACCCTCGCTAG
GAAAACGCTGCTGCCCCGTGGTGTTTTAGTAGGTATCGCCGCGGCCATCAAACTTACCCCGGCAGTTTTTGGCCTGTACT
TCCTGATCAAACGCGACTTTAAAGCCGCCGCCTGGTCTGTTGCCTCCGGCGTGGGGATGAGCGCACTTGCCTGGGGGATC
TCCCCAGAAAACTCTCGCAGCTACTGGCTCGATGTGCTGCACGACTCCAGCCGCATCGGCGAGTTGAGCTGGCCGTCCAA
CCAGTCCTTTAAAGGCGTGCTGGCGAGGCTATTCGGTGCAGATACCAGCGCGGTGCCGTGGGCCCTCCTATGCGTGGTCA
CCATCGTGCTGATCGCCTGGATCATGCACAAACTGCTTGCGCAGGAAACGTCGCAGGCAGCGGTTGTTGCTGTGTGTGTG
AACGCCTTGGTCGCCTTGCTGTGCTCGCCCGTGTCGTGGAGCCATCACTGGCTCTGGATCGTCTTTGCAGTTCAAACTGC
TCTTTTGGTGCTGGTGAACCAAAAAGATGCGCCACGACGCATGCTCGCAGCAGGCGCACTATCCGGTGTTGTGGCAATGA
TCTGCCAAGGGCACTGGCTGCTGCCCCGAAACGACCGCGCCGCTGAGCGCTGGCCGCTATGGCAACACATTATTGGTGAT
AGCTACGTGATCCTCGCGGTTGCCAGCCTCATAGCGATTGCCCTGTGGTTGGCAAAGCCGTGGACGGCTGCGCAGGATTG
TAGATACGCAGCCATCACCACCGGCGTGCTAGCAATCTACGCACTTACGTGCGCTGCCATCGCTATCGCCTAG

Upstream 100 bases:

>100_bases
GACGATTGCCGTGCGACCGCCGCTGTGCGCTGGTGGTTGAATGCGGGAGCACCTGGCGTGCCATTGTTGAACACAATGCT
GCATTGATACTGTTACACGC

Downstream 100 bases:

>100_bases
CTTCGTGCGTTTTTGCGCACGAGCTTTTCAAAGGTGTCGATGTAGCGCTGCACAAAGGCTGCGGTGTCAGGGACTAGCTT
GTCGCCGTCGAAAAGCGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-2)-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MMNNCDEHSLLRFLRWRGTMVVAWLVLATILVLGVMDHDALFMRKPIYGFDSLFIYHYDFGVYFEGAKAFAEHKNLYTQG
YQVHNISLPFTYPPFAALAFVPFTILPVRVAALLFDLGSVVALWWCSVLVTRAIVGQRPAWTRIDAYRLGLVVTAAAAVL
EPMRENIWFAQINVYLILLVLIDTLARKTLLPRGVLVGIAAAIKLTPAVFGLYFLIKRDFKAAAWSVASGVGMSALAWGI
SPENSRSYWLDVLHDSSRIGELSWPSNQSFKGVLARLFGADTSAVPWALLCVVTIVLIAWIMHKLLAQETSQAAVVAVCV
NALVALLCSPVSWSHHWLWIVFAVQTALLVLVNQKDAPRRMLAAGALSGVVAMICQGHWLLPRNDRAAERWPLWQHIIGD
SYVILAVASLIAIALWLAKPWTAAQDCRYAAITTGVLAIYALTCAAIAIA

Sequences:

>Translated_450_residues
MMNNCDEHSLLRFLRWRGTMVVAWLVLATILVLGVMDHDALFMRKPIYGFDSLFIYHYDFGVYFEGAKAFAEHKNLYTQG
YQVHNISLPFTYPPFAALAFVPFTILPVRVAALLFDLGSVVALWWCSVLVTRAIVGQRPAWTRIDAYRLGLVVTAAAAVL
EPMRENIWFAQINVYLILLVLIDTLARKTLLPRGVLVGIAAAIKLTPAVFGLYFLIKRDFKAAAWSVASGVGMSALAWGI
SPENSRSYWLDVLHDSSRIGELSWPSNQSFKGVLARLFGADTSAVPWALLCVVTIVLIAWIMHKLLAQETSQAAVVAVCV
NALVALLCSPVSWSHHWLWIVFAVQTALLVLVNQKDAPRRMLAAGALSGVVAMICQGHWLLPRNDRAAERWPLWQHIIGD
SYVILAVASLIAIALWLAKPWTAAQDCRYAAITTGVLAIYALTCAAIAIA
>Mature_450_residues
MMNNCDEHSLLRFLRWRGTMVVAWLVLATILVLGVMDHDALFMRKPIYGFDSLFIYHYDFGVYFEGAKAFAEHKNLYTQG
YQVHNISLPFTYPPFAALAFVPFTILPVRVAALLFDLGSVVALWWCSVLVTRAIVGQRPAWTRIDAYRLGLVVTAAAAVL
EPMRENIWFAQINVYLILLVLIDTLARKTLLPRGVLVGIAAAIKLTPAVFGLYFLIKRDFKAAAWSVASGVGMSALAWGI
SPENSRSYWLDVLHDSSRIGELSWPSNQSFKGVLARLFGADTSAVPWALLCVVTIVLIAWIMHKLLAQETSQAAVVAVCV
NALVALLCSPVSWSHHWLWIVFAVQTALLVLVNQKDAPRRMLAAGALSGVVAMICQGHWLLPRNDRAAERWPLWQHIIGD
SYVILAVASLIAIALWLAKPWTAAQDCRYAAITTGVLAIYALTCAAIAIA

Specific function: Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 49731; Mature: 49731

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNCDEHSLLRFLRWRGTMVVAWLVLATILVLGVMDHDALFMRKPIYGFDSLFIYHYDF
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEEEC
GVYFEGAKAFAEHKNLYTQGYQVHNISLPFTYPPFAALAFVPFTILPVRVAALLFDLGSV
CEEECCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALWWCSVLVTRAIVGQRPAWTRIDAYRLGLVVTAAAAVLEPMRENIWFAQINVYLILLV
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LIDTLARKTLLPRGVLVGIAAAIKLTPAVFGLYFLIKRDFKAAAWSVASGVGMSALAWGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECC
SPENSRSYWLDVLHDSSRIGELSWPSNQSFKGVLARLFGADTSAVPWALLCVVTIVLIAW
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IMHKLLAQETSQAAVVAVCVNALVALLCSPVSWSHHWLWIVFAVQTALLVLVNQKDAPRR
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
MLAAGALSGVVAMICQGHWLLPRNDRAAERWPLWQHIIGDSYVILAVASLIAIALWLAKP
HHHHHHHHHHHHHHHCCCEECCCCCCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC
WTAAQDCRYAAITTGVLAIYALTCAAIAIA
CCCHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMNNCDEHSLLRFLRWRGTMVVAWLVLATILVLGVMDHDALFMRKPIYGFDSLFIYHYDF
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEEEC
GVYFEGAKAFAEHKNLYTQGYQVHNISLPFTYPPFAALAFVPFTILPVRVAALLFDLGSV
CEEECCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALWWCSVLVTRAIVGQRPAWTRIDAYRLGLVVTAAAAVLEPMRENIWFAQINVYLILLV
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LIDTLARKTLLPRGVLVGIAAAIKLTPAVFGLYFLIKRDFKAAAWSVASGVGMSALAWGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECC
SPENSRSYWLDVLHDSSRIGELSWPSNQSFKGVLARLFGADTSAVPWALLCVVTIVLIAW
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IMHKLLAQETSQAAVVAVCVNALVALLCSPVSWSHHWLWIVFAVQTALLVLVNQKDAPRR
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
MLAAGALSGVVAMICQGHWLLPRNDRAAERWPLWQHIIGDSYVILAVASLIAIALWLAKP
HHHHHHHHHHHHHHHCCCEECCCCCCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC
WTAAQDCRYAAITTGVLAIYALTCAAIAIA
CCCHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]