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The map label for this gene is sodA

Identifier: 38234797

GI number: 38234797

Start: 2353492

End: 2354091

Strand: Direct

Name: sodA

Synonym: DIP2261

Alternate gene names: 38234797

Gene position: 2353492-2354091 (Clockwise)

Preceding gene: 38234795

Following gene: 38234798

Centisome position: 94.57

GC content: 54.33

Gene sequence:

>600_bases
ATGACGTACGCCCTTCCTGAACTCGATTACGCATACGACGCTCTCGAGCCACACATCGCTGCTGAGATCATGGAGCTGCA
CCACTCCAAGCACCACGCTAACTACGTGAACGGTGCAAATGCTGCTCTGGAGAAGCTGCAGAAGGCTCGCGAGAATGGTG
AGATCGGTGCTGTTGTTACCGCTTTGTCCAAGGATTTGGCTTTCAACTTGGGTGGCCACACCAACCACTCCATTTTCTGG
AAGAACCTCTCCCCTAACGGTGGCGGCGAGCCAACCGGCGCTTTGGCTGAGGCAATTGCCAAGGAGTTCGGTTCTTTTGA
GAAGTTCAAGGATCACTTCTCTGCTGCAGCTCTTGGTCTGCAGGGTTCCGGCTGGGCTGTTCTCGGCTACGATCACATCG
GTGGCCGTCTGGTTATCGAGCAGCTCACTGACCAGCAGGGCAACATCTCCGCTAACCTGACCCCACTTCTTATGCTCGAT
ATGTGGGAGCACGCTTTCTACCTTCAGTACAAGAACGTGAAGGCTGACTACGTCAAGGCTGTGTGGAACGTCTTCAACTG
GGATGACGTTGCTGCTCGTTTCGAGGCTGCTACCAAGTAA

Upstream 100 bases:

>100_bases
TCGTTTTTCTGACCACGAAAGACACATTTCGCCAAATAATTGTTGCCAAATGTGAGGATTCACCTATCATGGTAGGCACA
TCCAACGAAAGGAACGAAGA

Downstream 100 bases:

>100_bases
GCCGACGTAAGCCTGTGTAGCACTCAGTAGCGTTTCGCTACTGTGACTCTGAGTGAACAGAGCTCTTTTTCAAAGGCCCC
CCTATAACCAGGGGGCCTTT

Product: manganese superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVTALSKDLAFNLGGHTNHSIFW
KNLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGLQGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLD
MWEHAFYLQYKNVKADYVKAVWNVFNWDDVAARFEAATK

Sequences:

>Translated_199_residues
MTYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVTALSKDLAFNLGGHTNHSIFW
KNLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGLQGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLD
MWEHAFYLQYKNVKADYVKAVWNVFNWDDVAARFEAATK
>Mature_198_residues
TYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVTALSKDLAFNLGGHTNHSIFWK
NLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGLQGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLDM
WEHAFYLQYKNVKADYVKAVWNVFNWDDVAARFEAATK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family

Homologues:

Organism=Homo sapiens, GI67782307, Length=200, Percent_Identity=56.5, Blast_Score=229, Evalue=1e-60,
Organism=Homo sapiens, GI67782305, Length=200, Percent_Identity=56.5, Blast_Score=229, Evalue=1e-60,
Organism=Homo sapiens, GI67782309, Length=200, Percent_Identity=44, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1790342, Length=209, Percent_Identity=44.4976076555024, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1787946, Length=196, Percent_Identity=39.7959183673469, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17506561, Length=198, Percent_Identity=46.969696969697, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17569479, Length=197, Percent_Identity=44.6700507614213, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321796, Length=203, Percent_Identity=45.320197044335, Blast_Score=174, Evalue=6e-45,
Organism=Drosophila melanogaster, GI17136812, Length=198, Percent_Identity=46.969696969697, Blast_Score=195, Evalue=2e-50,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SODM_CORDI (P42821)

Other databases:

- EMBL:   BX248360
- EMBL:   X81382
- PIR:   I40677
- RefSeq:   NP_940564.1
- ProteinModelPortal:   P42821
- SMR:   P42821
- GeneID:   2650057
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP2261
- NMPDR:   fig|257309.1.peg.2155
- HOGENOM:   HBG507761
- OMA:   QTSPRTE
- PhylomeDB:   P42821
- ProtClustDB:   CLSK634035
- BioCyc:   CDIP257309:DIP2261-MONOMER
- BRENDA:   1.15.1.1
- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831
- PANTHER:   PTHR11404
- PIRSF:   PIRSF000349
- PRINTS:   PR01703

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N; SSF46609 SODismutase; SSF54719 SODismutase

EC number: =1.15.1.1

Molecular weight: Translated: 21887; Mature: 21756

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVT
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHH
ALSKDLAFNLGGHTNHSIFWKNLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGL
HHHHHHEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
QGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLDMWEHAFYLQYKNVKADYVKA
CCCCEEEEEECCCCCEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHH
VWNVFNWDDVAARFEAATK
HHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVT
CCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHH
ALSKDLAFNLGGHTNHSIFWKNLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGL
HHHHHHEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
QGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLDMWEHAFYLQYKNVKADYVKA
CCCCEEEEEECCCCCEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHH
VWNVFNWDDVAARFEAATK
HHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910; 7852575