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The map label for this gene is yrbD [H]

Identifier: 38234787

GI number: 38234787

Start: 2342131

End: 2343621

Strand: Reverse

Name: yrbD [H]

Synonym: DIP2251

Alternate gene names: 38234787

Gene position: 2343621-2342131 (Counterclockwise)

Preceding gene: 38234789

Following gene: 38234785

Centisome position: 94.17

GC content: 58.28

Gene sequence:

>1491_bases
ATGAATACGCTCATCGAAACCCTTAATTCGATCATCTGGTCACCCTTCCTTGTTTTTCTCTGCCTCGGAGCAGGCCTGTA
CTTCACCATTGCCACCAAGTGCGTTCAAGTAACCGGCCTCCCCGACATGCTTCGCCAGCTCCGCGCCGGTGAAAAATCAG
CAAACGGTGTGTCCTCCTTCCAATCCCTCATGATGTCCCTCGCCGGACGCGTGGGGGTTGGAAACATCGCCGGTGTGGCA
ACCGCCATCGCCTTCGGCGGACCCGGTGCCGTGTTCTGGATGTGGGCCGTCGCCTTCCTCGGCGCTGCCACTTCCTTTAT
CGAATGCACCCTCGCCCAAATCTACAAAGAGCGCGACCAAGACACCGGCGAATACCGTGGCGGACCGGCCTACTACATTG
AGAAAAGCCTCAAGCACACCAAAGCAGCCCCCTTCATGCTGTTCTACGCCATCGCCTTCGCAGTGGTCATGATCTTCTCC
ACCAGCTACTTCATGCCGGGTGTGCAGGCCAACGGTGTGGCGTCGGCAATGCACAACGCATGGAACCTTGACGTTCGCAT
CGTCGGCGCATTCCTCACCGTGCTACTCGCCCTCATCATCTTCGGCGGCGTGAAGCGCATCGCCTGGTTTGCGTCGTTAG
TCGTGCCCTTCATGGCCATGGTCTACATCATCATCGCGCTCGTGGTGCTCTTCATGCACTTCGACCAAATCCCACACGTA
TTTGGCACCATCTTCAGCTCCGCATTCAACGCCAACGCCACCTTCTCCGGACTCCTCGGCTCCGCCATCATGTGGGGCGT
ACGCCGCGGCATCTACTCCAACGAAGCAGGCCAAGGCCTCAACCCCCAAGCCGCAGCCGCAGCCGAAGTATCCCACCCCG
CAAAACAAGGCTTCGCACAAGCCTTCGCCGTCTACGTAGACACCCTCTTCGTCTGCTCCGCAACCGCCTTCATCATCATC
TCCACCGACATGTACCGCGTCTTCGAAGGCGGCACCGAAGACAGCCCCGTGCGCTACGCAGGCTCCCTACCAAGCAACAC
CCCCGTGGGACCAGGATTCGTTCAACAAGGCCTCGACTCCGTCGCCTCAGGTGTCGGACCATCTTTTATCGGCGTAGCCA
TCCTCTTCTTCGGCTTCACCACCATCTTGTCCTACTACTACATCTCCGAAACCAACTTCACCTACCTCATGCGCTGGATC
TCCAACGCAACCGCAAGGCGCGCCACCATCTTCGGCCTGCGCTGCCTGATGCTGGTATCCGTTTGGATCGGTGCAGTATC
TACCCCAGGTGCTGCATGGGCATTGGGTGACATTGGAGCGGGTGCCACCGCATGGCTCAACGTGATCGCCATCCTGATCC
TGCAGGTCCCAGCTATTAAGTGCCTGCGCGACTACAACGAGCAGAAGAAAGCCGGACTGGATCCACAATTTGATCCTGCT
GCGGTGGGAATCAAGAACGCTGAGTTCTGGGAGACATACAAAGCTCGCTAA

Upstream 100 bases:

>100_bases
CTCTGCTTTATTAGTGGTAGGGGGTACGGTGATGCACATTAAATCTGTTGGATGATAGGTTGTAAGACACTCTTATTGTC
AGGAAACTCCGGAGCACAGC

Downstream 100 bases:

>100_bases
CGGCGGCTAAAGCCAAAAGTGAGTAGTTCGTGCCAAATTAAATCTTTTCTAATATCTCCGACCTGCGGAAACGTCGCGGA
GGTGAAAAAGATTTGGCACG

Product: putative sodium/alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MNTLIETLNSIIWSPFLVFLCLGAGLYFTIATKCVQVTGLPDMLRQLRAGEKSANGVSSFQSLMMSLAGRVGVGNIAGVA
TAIAFGGPGAVFWMWAVAFLGAATSFIECTLAQIYKERDQDTGEYRGGPAYYIEKSLKHTKAAPFMLFYAIAFAVVMIFS
TSYFMPGVQANGVASAMHNAWNLDVRIVGAFLTVLLALIIFGGVKRIAWFASLVVPFMAMVYIIIALVVLFMHFDQIPHV
FGTIFSSAFNANATFSGLLGSAIMWGVRRGIYSNEAGQGLNPQAAAAAEVSHPAKQGFAQAFAVYVDTLFVCSATAFIII
STDMYRVFEGGTEDSPVRYAGSLPSNTPVGPGFVQQGLDSVASGVGPSFIGVAILFFGFTTILSYYYISETNFTYLMRWI
SNATARRATIFGLRCLMLVSVWIGAVSTPGAAWALGDIGAGATAWLNVIAILILQVPAIKCLRDYNEQKKAGLDPQFDPA
AVGIKNAEFWETYKAR

Sequences:

>Translated_496_residues
MNTLIETLNSIIWSPFLVFLCLGAGLYFTIATKCVQVTGLPDMLRQLRAGEKSANGVSSFQSLMMSLAGRVGVGNIAGVA
TAIAFGGPGAVFWMWAVAFLGAATSFIECTLAQIYKERDQDTGEYRGGPAYYIEKSLKHTKAAPFMLFYAIAFAVVMIFS
TSYFMPGVQANGVASAMHNAWNLDVRIVGAFLTVLLALIIFGGVKRIAWFASLVVPFMAMVYIIIALVVLFMHFDQIPHV
FGTIFSSAFNANATFSGLLGSAIMWGVRRGIYSNEAGQGLNPQAAAAAEVSHPAKQGFAQAFAVYVDTLFVCSATAFIII
STDMYRVFEGGTEDSPVRYAGSLPSNTPVGPGFVQQGLDSVASGVGPSFIGVAILFFGFTTILSYYYISETNFTYLMRWI
SNATARRATIFGLRCLMLVSVWIGAVSTPGAAWALGDIGAGATAWLNVIAILILQVPAIKCLRDYNEQKKAGLDPQFDPA
AVGIKNAEFWETYKAR
>Mature_496_residues
MNTLIETLNSIIWSPFLVFLCLGAGLYFTIATKCVQVTGLPDMLRQLRAGEKSANGVSSFQSLMMSLAGRVGVGNIAGVA
TAIAFGGPGAVFWMWAVAFLGAATSFIECTLAQIYKERDQDTGEYRGGPAYYIEKSLKHTKAAPFMLFYAIAFAVVMIFS
TSYFMPGVQANGVASAMHNAWNLDVRIVGAFLTVLLALIIFGGVKRIAWFASLVVPFMAMVYIIIALVVLFMHFDQIPHV
FGTIFSSAFNANATFSGLLGSAIMWGVRRGIYSNEAGQGLNPQAAAAAEVSHPAKQGFAQAFAVYVDTLFVCSATAFIII
STDMYRVFEGGTEDSPVRYAGSLPSNTPVGPGFVQQGLDSVASGVGPSFIGVAILFFGFTTILSYYYISETNFTYLMRWI
SNATARRATIFGLRCLMLVSVWIGAVSTPGAAWALGDIGAGATAWLNVIAILILQVPAIKCLRDYNEQKKAGLDPQFDPA
AVGIKNAEFWETYKAR

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=479, Percent_Identity=36.1169102296451, Blast_Score=252, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 53379; Mature: 53379

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCHHHHHHHCCC
>Mature Secondary Structure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HCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]