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The map label for this gene is glpD [H]

Identifier: 38234773

GI number: 38234773

Start: 2325345

End: 2327078

Strand: Reverse

Name: glpD [H]

Synonym: DIP2237

Alternate gene names: 38234773

Gene position: 2327078-2325345 (Counterclockwise)

Preceding gene: 38234774

Following gene: 38234772

Centisome position: 93.51

GC content: 61.65

Gene sequence:

>1734_bases
GTGGCAACTATGACCACGAAATCCCATTGCACATTCAACCCCGACTACTACCAGGACGTCTGGCAGCGCTTCGGTGAAGA
AGAATACGACGTTGTCGTCATCGGTGGCGGCTCCGTCGGCGCAGGCGCAGGCCTCGACGCAGCCATCCGCGGCCTCAAAG
TGGCCGTCGTAGAGTCCCGAGACTTCGCAGCCGGCACCTCCTCACGATCATCAAAAATGTTCCACGGTGGCCTGCGATAT
CTCGCCATGCTGGACTTCAAGCTAGTGGCCGAATCCCTCCACGAGCGCGAACTCAACATGTCGACGCTCGCACCGCACCT
AGTCAAGCCGCTGAAATTCCTCTTCCCCCTCACACACCACGTGTGGGAACGGGTGATGATGTTCGGCGGCTTTACTCTTT
ACGACCTCATGGGCGGCGCAAAATCAGTCCCCATGCAAAAGCACTACTCCCGCAAGGGAACACTCGCCATGGCCCCAGGA
CTAAAAGACGACGCTGTGGTCGGATCCGTCCGCTACTTTGACACGCTTGTCGACGACGCCCGCCACACCATGACAGTCCT
ACGCACCGCCGGCGAACTCGGCGCAGATGTTCGCCCCTCCACCCAAGTAGTCGGCTTTGAAAAAGACGGCCAACGCGTGG
TCGGCGCCATCCTCCAAGACACCGACACCGGCGAACAAACCACCATCCGCGGCAAGGTATTCATCAACGCCACCGGCGTA
TGGAACGACCACATTGAAAAGCTCGCCGGCGGCAACGGCCCCTTCTCGGTCCACGCCTCCAAGGGCGTACACATCGTGGT
ACCAAAGAACGTCTTTGATGCCGACGCAGCCATGTGCTTTGTCACCGAAAAGTCCGTGCTCTTCGTGATCCCATGGGGTG
AATACTGGATCATCGGCACCACCGACACCGACTGGGATCTCAACCGCGCAGACCCCGCACCAACTGCCGCCGACATCAAC
TACATCCTCGACGAAGTCAACCAGCGAGTCCGCCGGCCCATCCAACACTCCGACATCGTCGGCGTGTACTCCGGACTCCG
CCCGCTGCTCTCCGGCAAATCCGACACCACCACCAAGCTGTCGCGCAACCACGCCGTAGCAAAGGTCATGCCTGGACTCG
TCTCCGTCGCCGGCGGTAAGTACACCACCTACCGTGTGATCGGCAAGGATGCAGTCGACCTCGCCACCGAAGACTTGGAC
TTCCGCGTACCAGCCTCCGAATCGGAACGCACCCCGATCCTCGGTGCCGACGGCTACCACGCCCTACAAAACCAAGCACC
ACGCATCGCCCGCACCTTCGGCACCACAGAGGACGTCGTCGAGCACCTGCTCGGCCGCTACGGCTCCCTCGTCCATGAGG
TCCTAGAACCGAGCGTCGATAAACCTGAGCTGCTCGAACCCATCCCAGGCGCGCCGGGCTACATTAAAGCAGAGGCCGTC
TATGCCGTCACCCACGAGGGTGCCCTGCACGTCGAGGACATCGTGGAACGTCGCCTACGTGCCGGCATCGAATACGCCGA
CCGTGGCGTTGCCGCAGCTCCCGCCATCGCCGAGCTCGTTGCCGACTACCTTGGCTGGGACGCCGAGCGCACCGCCGCCG
AGGTCACCGCGTTCACCGACCGCGTGTCCGCCGAAATCGCCGCCGAGAAGGAGCTCACTGACAAAGCCGCCAACGAGCAC
ATCGTGGCAGGCTCCGCGGTGCGCAGCTATGTGGATGTGTCAGGTGATAACTAA

Upstream 100 bases:

>100_bases
TGTTATCATCTCCGAAACTAAAAAACTTGCTCTAGGGGTCTAGTCTGCCTAACTTACGGTTCAGTAGGGTTGGGGCAAAC
CTCGGACGCAAAGAAGGAGT

Downstream 100 bases:

>100_bases
TGACCGCCCTACAAGCATTCGGCTGGGAGTTTTTGGGCACAGCCCTCCTGCTTCTCCTCGGTAACGGCGTTTGCGCCGTC
AACAGCCTGCGCACCTCCGC

Product: putative glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MATMTTKSHCTFNPDYYQDVWQRFGEEEYDVVVIGGGSVGAGAGLDAAIRGLKVAVVESRDFAAGTSSRSSKMFHGGLRY
LAMLDFKLVAESLHERELNMSTLAPHLVKPLKFLFPLTHHVWERVMMFGGFTLYDLMGGAKSVPMQKHYSRKGTLAMAPG
LKDDAVVGSVRYFDTLVDDARHTMTVLRTAGELGADVRPSTQVVGFEKDGQRVVGAILQDTDTGEQTTIRGKVFINATGV
WNDHIEKLAGGNGPFSVHASKGVHIVVPKNVFDADAAMCFVTEKSVLFVIPWGEYWIIGTTDTDWDLNRADPAPTAADIN
YILDEVNQRVRRPIQHSDIVGVYSGLRPLLSGKSDTTTKLSRNHAVAKVMPGLVSVAGGKYTTYRVIGKDAVDLATEDLD
FRVPASESERTPILGADGYHALQNQAPRIARTFGTTEDVVEHLLGRYGSLVHEVLEPSVDKPELLEPIPGAPGYIKAEAV
YAVTHEGALHVEDIVERRLRAGIEYADRGVAAAPAIAELVADYLGWDAERTAAEVTAFTDRVSAEIAAEKELTDKAANEH
IVAGSAVRSYVDVSGDN

Sequences:

>Translated_577_residues
MATMTTKSHCTFNPDYYQDVWQRFGEEEYDVVVIGGGSVGAGAGLDAAIRGLKVAVVESRDFAAGTSSRSSKMFHGGLRY
LAMLDFKLVAESLHERELNMSTLAPHLVKPLKFLFPLTHHVWERVMMFGGFTLYDLMGGAKSVPMQKHYSRKGTLAMAPG
LKDDAVVGSVRYFDTLVDDARHTMTVLRTAGELGADVRPSTQVVGFEKDGQRVVGAILQDTDTGEQTTIRGKVFINATGV
WNDHIEKLAGGNGPFSVHASKGVHIVVPKNVFDADAAMCFVTEKSVLFVIPWGEYWIIGTTDTDWDLNRADPAPTAADIN
YILDEVNQRVRRPIQHSDIVGVYSGLRPLLSGKSDTTTKLSRNHAVAKVMPGLVSVAGGKYTTYRVIGKDAVDLATEDLD
FRVPASESERTPILGADGYHALQNQAPRIARTFGTTEDVVEHLLGRYGSLVHEVLEPSVDKPELLEPIPGAPGYIKAEAV
YAVTHEGALHVEDIVERRLRAGIEYADRGVAAAPAIAELVADYLGWDAERTAAEVTAFTDRVSAEIAAEKELTDKAANEH
IVAGSAVRSYVDVSGDN
>Mature_576_residues
ATMTTKSHCTFNPDYYQDVWQRFGEEEYDVVVIGGGSVGAGAGLDAAIRGLKVAVVESRDFAAGTSSRSSKMFHGGLRYL
AMLDFKLVAESLHERELNMSTLAPHLVKPLKFLFPLTHHVWERVMMFGGFTLYDLMGGAKSVPMQKHYSRKGTLAMAPGL
KDDAVVGSVRYFDTLVDDARHTMTVLRTAGELGADVRPSTQVVGFEKDGQRVVGAILQDTDTGEQTTIRGKVFINATGVW
NDHIEKLAGGNGPFSVHASKGVHIVVPKNVFDADAAMCFVTEKSVLFVIPWGEYWIIGTTDTDWDLNRADPAPTAADINY
ILDEVNQRVRRPIQHSDIVGVYSGLRPLLSGKSDTTTKLSRNHAVAKVMPGLVSVAGGKYTTYRVIGKDAVDLATEDLDF
RVPASESERTPILGADGYHALQNQAPRIARTFGTTEDVVEHLLGRYGSLVHEVLEPSVDKPELLEPIPGAPGYIKAEAVY
AVTHEGALHVEDIVERRLRAGIEYADRGVAAAPAIAELVADYLGWDAERTAAEVTAFTDRVSAEIAAEKELTDKAANEHI
VAGSAVRSYVDVSGDN

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=558, Percent_Identity=33.1541218637993, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI285002231, Length=558, Percent_Identity=33.1541218637993, Blast_Score=272, Evalue=6e-73,
Organism=Escherichia coli, GI2367226, Length=471, Percent_Identity=31.4225053078556, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1788574, Length=371, Percent_Identity=26.4150943396226, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI115534726, Length=523, Percent_Identity=33.2695984703633, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17509253, Length=557, Percent_Identity=31.4183123877917, Blast_Score=230, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6322036, Length=586, Percent_Identity=29.3515358361775, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI161077125, Length=568, Percent_Identity=31.5140845070423, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24653942, Length=568, Percent_Identity=31.5140845070423, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24653944, Length=568, Percent_Identity=31.5140845070423, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI20130025, Length=568, Percent_Identity=31.5140845070423, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24586295, Length=564, Percent_Identity=31.5602836879433, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19921278, Length=535, Percent_Identity=28.9719626168224, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI45550977, Length=396, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62655; Mature: 62524

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMTTKSHCTFNPDYYQDVWQRFGEEEYDVVVIGGGSVGAGAGLDAAIRGLKVAVVESR
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHCCEEEEEEECC
DFAAGTSSRSSKMFHGGLRYLAMLDFKLVAESLHERELNMSTLAPHLVKPLKFLFPLTHH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VWERVMMFGGFTLYDLMGGAKSVPMQKHYSRKGTLAMAPGLKDDAVVGSVRYFDTLVDDA
HHHHHHHHCCHHHHHHHCCCCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
RHTMTVLRTAGELGADVRPSTQVVGFEKDGQRVVGAILQDTDTGEQTTIRGKVFINATGV
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEECC
WNDHIEKLAGGNGPFSVHASKGVHIVVPKNVFDADAAMCFVTEKSVLFVIPWGEYWIIGT
CHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCEEEEEC
TDTDWDLNRADPAPTAADINYILDEVNQRVRRPIQHSDIVGVYSGLRPLLSGKSDTTTKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
SRNHAVAKVMPGLVSVAGGKYTTYRVIGKDAVDLATEDLDFRVPASESERTPILGADGYH
HHCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCEECCCCCCCCCCEECCCCHH
ALQNQAPRIARTFGTTEDVVEHLLGRYGSLVHEVLEPSVDKPELLEPIPGAPGYIKAEAV
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEEEE
YAVTHEGALHVEDIVERRLRAGIEYADRGVAAAPAIAELVADYLGWDAERTAAEVTAFTD
EEEECCCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RVSAEIAAEKELTDKAANEHIVAGSAVRSYVDVSGDN
HHHHHHHHHHHHHHHHCCCEEEECHHHHHHEECCCCC
>Mature Secondary Structure 
ATMTTKSHCTFNPDYYQDVWQRFGEEEYDVVVIGGGSVGAGAGLDAAIRGLKVAVVESR
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHCCEEEEEEECC
DFAAGTSSRSSKMFHGGLRYLAMLDFKLVAESLHERELNMSTLAPHLVKPLKFLFPLTHH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VWERVMMFGGFTLYDLMGGAKSVPMQKHYSRKGTLAMAPGLKDDAVVGSVRYFDTLVDDA
HHHHHHHHCCHHHHHHHCCCCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
RHTMTVLRTAGELGADVRPSTQVVGFEKDGQRVVGAILQDTDTGEQTTIRGKVFINATGV
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEECC
WNDHIEKLAGGNGPFSVHASKGVHIVVPKNVFDADAAMCFVTEKSVLFVIPWGEYWIIGT
CHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCEEEEEC
TDTDWDLNRADPAPTAADINYILDEVNQRVRRPIQHSDIVGVYSGLRPLLSGKSDTTTKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
SRNHAVAKVMPGLVSVAGGKYTTYRVIGKDAVDLATEDLDFRVPASESERTPILGADGYH
HHCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCEECCCCCCCCCCEECCCCHH
ALQNQAPRIARTFGTTEDVVEHLLGRYGSLVHEVLEPSVDKPELLEPIPGAPGYIKAEAV
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEEEE
YAVTHEGALHVEDIVERRLRAGIEYADRGVAAAPAIAELVADYLGWDAERTAAEVTAFTD
EEEECCCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RVSAEIAAEKELTDKAANEHIVAGSAVRSYVDVSGDN
HHHHHHHHHHHHHHHHCCCEEEECHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]