Click here to switch to the map view.

The map label for this gene is era

Identifier: 38234285

GI number: 38234285

Start: 1750848

End: 1751765

Strand: Reverse

Name: era

Synonym: DIP1714

Alternate gene names: 38234285

Gene position: 1751765-1750848 (Counterclockwise)

Preceding gene: 38234286

Following gene: 38234284

Centisome position: 70.39

GC content: 52.72

Gene sequence:

>918_bases
GTGAGCTTCACCGACACACCCGAGGGATTTCGCTCTGGTTTTATTAGCTTCGTTGGACGACCCAACACCGGAAAATCTAC
GCTGACCAACGCTTTGGTAGGGGAGAAGATTGCGATCACGGCTAACCAGCCGGAGACAACGCGACACCCCATTCGTGGCA
TCGTGCATCGCGAGGATGCGCAGATCATCGTGGTAGATACCCCTGGTTTACATAAGCCACGCACGTTGTTGGGTGAACGC
CTTAACGAGGTTGTGAAAGATACCTATGCCGATATGGATCTTATTGCCATCACGGTTCCTGCTGATGAGAAGATCGGCCC
AGGTGATCGCTGGATTCTTGATGCGGTAAAGAAGGTAGCACCTAAGACACCGCTGCTGGGCATCGTTACCAAGGTTGATA
AGGCAAGTCGTGATCAGGTGGCAGTGCAGCTCATGGAGCTTCACGAGCTGCTCGGCGGTAATTCTGAGGTAGTGCCAGTT
TCTGCCGTTACCGGTGAACAACGTGACGTGCTTCTCGACGTGATCACGCGGCTGCTGCCAGAAGGTCCGAAGTTCTACCC
TGATGATCACATCACTGACGATGACACGGAGACTCGACTTTCTGAGCTGATTCGTGAGGCCGCATTGAGCGGACTCAAAG
ATGAGCTTCCGCACTCCGTAGCGGTGCAAATTGATGAGATCTTGCCAAACGATGAGCGTGAGGGAGTTCTCGACGTTCAT
GCGGTGATCTATGTTGAGCGTCCAGGACAAAAATCGATCCTGATCGGTAAAGATGGCCGCCGCCTTGGTCGCATCATTCA
CAATGCGCGCCCAGAAATCATCAAGATTTTGGGAAGCAATGTGTACTTGGATCTTCGTATCAAGGTGCTCAAGAACTGGC
AGCAGGATCCAAAGCAGCTAGGCCGACTAGGGTTCTAG

Upstream 100 bases:

>100_bases
AGCCATTGCACATCCTCGCCTTCAGTTTGAGGTTGAGCAGATCGCCTAACATTGGCATAGAATCACTTTTTAAGTTCTTT
CACACAACATAAGGAGATAG

Downstream 100 bases:

>100_bases
TGCGTCGAGAAAGTTATAGGGAGCGAGCCCTTGTGGTTCGCTCCTACGACTTTGGTGAGGCAGACCGCATCATAGTGCTT
TTTACCCGCGGTCGTGGCAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDAQIIVVDTPGLHKPRTLLGER
LNEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVAPKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPV
SAVTGEQRDVLLDVITRLLPEGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVH
AVIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQLGRLGF

Sequences:

>Translated_305_residues
MSFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDAQIIVVDTPGLHKPRTLLGER
LNEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVAPKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPV
SAVTGEQRDVLLDVITRLLPEGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVH
AVIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQLGRLGF
>Mature_304_residues
SFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDAQIIVVDTPGLHKPRTLLGERL
NEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVAPKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPVS
AVTGEQRDVLLDVITRLLPEGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVHA
VIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQLGRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=36.4548494983278, Blast_Score=174, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_CORDI (Q6NG20)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940052.1
- HSSP:   Q9X1F8
- ProteinModelPortal:   Q6NG20
- SMR:   Q6NG20
- GeneID:   2650307
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1714
- NMPDR:   fig|257309.1.peg.1643
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   CDIP257309:DIP1714-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PRINTS:   PR00326
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33742; Mature: 33611

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDA
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHEEECCC
QIIVVDTPGLHKPRTLLGERLNEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHC
PKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPVSAVTGEQRDVLLDVITRLLP
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCC
EGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCHHEEEEHHHCCCCCCCCEEEEE
AVIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQL
EEEEEECCCCCEEEECCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHCCCCCHHHH
GRLGF
CCCCC
>Mature Secondary Structure 
SFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDA
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHEEECCC
QIIVVDTPGLHKPRTLLGERLNEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHC
PKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPVSAVTGEQRDVLLDVITRLLP
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCC
EGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCHHEEEEHHHCCCCCCCCEEEEE
AVIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQL
EEEEEECCCCCEEEECCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHCCCCCHHHH
GRLGF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14602910