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The map label for this gene is tsnR [H]

Identifier: 38233754

GI number: 38233754

Start: 1154597

End: 1155415

Strand: Direct

Name: tsnR [H]

Synonym: DIP1164

Alternate gene names: 38233754

Gene position: 1154597-1155415 (Clockwise)

Preceding gene: 38233752

Following gene: 38233755

Centisome position: 46.39

GC content: 48.84

Gene sequence:

>819_bases
ATGCCGATTGATTTTTCCTCTCCTTTTACTGAAAGAACCCCTCGTGTAGTGAACGCCGCTAAACTCTTGCGTTCTGCAGG
CCGTAAGAAGGTTGATCGTTTTCTTGCTGAAGGGGAAAATTCAGTTGAGGCTGCAGTTGCTACGGGTGCTGCGACGGACC
TTTTTGTTACCGAAAAAGCTGCTGAGCGATTTGAAGCAATCGTCACAGCTGCAGGGCATATGGGGGTTTTTGTTCATCCG
ATTACTGATCGCGCCGCAAAGAGTTTGTCGGATACCATGACCACTACAGGGATTTTTGCAGTTTGTCTACCAGTATTGTG
GAGTGCTCGAGAAGCGCTAAAAGGTAATCCATCATTGGTATGCGTGGCGGTCGAAACTGGTGAGCCTGGTAATGCAGGTA
CGTTGGTTCGTGTGGCAGACGCTATGGGAGCAGACTGCGTGATATTCGCGGGAACAACGGTAGATCCGCAATCGCCAAAG
GCTGTCAGGGCAAGTGCTGGATCTTTATTCCACATTCCTGTCGTGAGAGAACCAGACATGCAAAAAGTATGGCAGATTCT
TCGGGCTCGAAATGTGCAGATGTTAGCAACGGCTGCTCAAGGTGAAATTAACTTGGACACAGCAGGTGAATTGTTAGAAA
AGCCCACGGCATGGCTGATGGGAAATGAGGCTCATGGGCTCAATGATGAGGCATTGTCTGCTGCGGATCATTCGGTTCGT
ATTCCCATTCGTGGTAGGGCAGAGTCTCTCAACCTCGCAACTGCTGCAAGTATTTGTATGTACGAGTCTTCAAAATCACA
AGCTCACAAAGACAACTGA

Upstream 100 bases:

>100_bases
ATTTTAGTCAGGCACATGGATATGGTATGTGATAGGTCCACAATTGAATATTGTGGTCAACTAGGGGCTTATTTGGGACG
CGCTGATAGGGTAGGAAACT

Downstream 100 bases:

>100_bases
GTAGGTGAATTCCTCGCACGAGTAATTGGCTTACTTTCCAGTAGTGGGTGAGTTGGCTCTTGGCTTGGCATAACGGGGTA
TGATGTCATGGTTATCTATA

Product: putative rRNA methyltransferase

Products: S-adenosyl-L-homocysteine; tRNATyr Containing 2'-O-methylguanosine [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPIDFSSPFTERTPRVVNAAKLLRSAGRKKVDRFLAEGENSVEAAVATGAATDLFVTEKAAERFEAIVTAAGHMGVFVHP
ITDRAAKSLSDTMTTTGIFAVCLPVLWSAREALKGNPSLVCVAVETGEPGNAGTLVRVADAMGADCVIFAGTTVDPQSPK
AVRASAGSLFHIPVVREPDMQKVWQILRARNVQMLATAAQGEINLDTAGELLEKPTAWLMGNEAHGLNDEALSAADHSVR
IPIRGRAESLNLATAASICMYESSKSQAHKDN

Sequences:

>Translated_272_residues
MPIDFSSPFTERTPRVVNAAKLLRSAGRKKVDRFLAEGENSVEAAVATGAATDLFVTEKAAERFEAIVTAAGHMGVFVHP
ITDRAAKSLSDTMTTTGIFAVCLPVLWSAREALKGNPSLVCVAVETGEPGNAGTLVRVADAMGADCVIFAGTTVDPQSPK
AVRASAGSLFHIPVVREPDMQKVWQILRARNVQMLATAAQGEINLDTAGELLEKPTAWLMGNEAHGLNDEALSAADHSVR
IPIRGRAESLNLATAASICMYESSKSQAHKDN
>Mature_271_residues
PIDFSSPFTERTPRVVNAAKLLRSAGRKKVDRFLAEGENSVEAAVATGAATDLFVTEKAAERFEAIVTAAGHMGVFVHPI
TDRAAKSLSDTMTTTGIFAVCLPVLWSAREALKGNPSLVCVAVETGEPGNAGTLVRVADAMGADCVIFAGTTVDPQSPKA
VRASAGSLFHIPVVREPDMQKVWQILRARNVQMLATAAQGEINLDTAGELLEKPTAWLMGNEAHGLNDEALSAADHSVRI
PIRGRAESLNLATAASICMYESSKSQAHKDN

Specific function: Specifically Methylates Guanosine-18 In Various tRNAs. [C]

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.34 [C]

Molecular weight: Translated: 28823; Mature: 28692

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDFSSPFTERTPRVVNAAKLLRSAGRKKVDRFLAEGENSVEAAVATGAATDLFVTEKA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHEEEHHH
AERFEAIVTAAGHMGVFVHPITDRAAKSLSDTMTTTGIFAVCLPVLWSAREALKGNPSLV
HHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
CVAVETGEPGNAGTLVRVADAMGADCVIFAGTTVDPQSPKAVRASAGSLFHIPVVREPDM
EEEEECCCCCCCCCEEEEHHHCCCCEEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCCH
QKVWQILRARNVQMLATAAQGEINLDTAGELLEKPTAWLMGNEAHGLNDEALSAADHSVR
HHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCEEE
IPIRGRAESLNLATAASICMYESSKSQAHKDN
EEECCCCCCCCHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure 
PIDFSSPFTERTPRVVNAAKLLRSAGRKKVDRFLAEGENSVEAAVATGAATDLFVTEKA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHEEEHHH
AERFEAIVTAAGHMGVFVHPITDRAAKSLSDTMTTTGIFAVCLPVLWSAREALKGNPSLV
HHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
CVAVETGEPGNAGTLVRVADAMGADCVIFAGTTVDPQSPKAVRASAGSLFHIPVVREPDM
EEEEECCCCCCCCCEEEEHHHCCCCEEEEECCCCCCCCCCHHHHCCCCEEEECCCCCCCH
QKVWQILRARNVQMLATAAQGEINLDTAGELLEKPTAWLMGNEAHGLNDEALSAADHSVR
HHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCEEE
IPIRGRAESLNLATAASICMYESSKSQAHKDN
EEECCCCCCCCHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; tRNATyr [C]

Specific reaction: S-Adenosyl-L-methionine + tRNATyr = S-adenosyl-L-homocysteine + tRNATyr Containing 2'-O-methylguanosine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]