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The map label for this gene is czcD [H]

Identifier: 38233695

GI number: 38233695

Start: 1085794

End: 1086717

Strand: Direct

Name: czcD [H]

Synonym: DIP1101

Alternate gene names: 38233695

Gene position: 1085794-1086717 (Clockwise)

Preceding gene: 38233694

Following gene: 38233696

Centisome position: 43.63

GC content: 48.81

Gene sequence:

>924_bases
ATGAGCAACCATCACCATGACCACCATAACCACCATGACCATCACCACGGAGCACCGTCGAGTAGCCGTGCTTTGTTGCT
GGTTGCCGGCCTTACATTCGCCTTCTTCATTGTTGAGCTCGTCGGTGGTGCACTAGCCAAATCTTTGGCTTTGATGTCTG
ATGCCCTGCATATGCTGTCAGACTCCACGGGACTTATCATCGCACTTATTGCGGTTGTGATTGGGCGGAGAAAGGCTACG
TCGCAAGCAACCTATGGATATAAACGCATTGAAGTTTTAGCAGCCTTGGTCAATGCTTTATCCGTTACCTTTATTACTGG
GTGGATTGTCCTCGAGGCTATCCGCAGGCTTTCATCGCATACTGTGATCGATACGAGAACCACAATGGTTATTGCCATAA
TCGGACTCGTATTCAACATAGTGGGGGCGGTGGTCCTTCATGGACACAGCCATGAAGGGGTTAACGTCAAAGGCGCTTAC
CTTCATATTTTGGTGGACCTGGGAGGCTCGGTCGCGGTCATCGTTTCGTCGTTGCTGATTATGACTACAGGCTGGATGTG
GTGCGATACGGCTGTGTCGGTATTGCTCGCAGTAATAATTTTGCCGCGTTCCTTGTCCTTAGTTCGTTCTACGCTGGGTA
TTTTGATGGAACGAGTTCCCAAGACTGTCGATGTTGAGACAATTCGATCACGGATTGCGCAAATTGATGGAGTAGGCGGC
GTTCACGACGTTCATGTTTGGTCAATTGATGGACAACAAGACATAGCAACGGTCCACGTTGTGGTCGATGAGAACGTCAA
CGTTAAAGATTGCACGACTCTAGATCGGATACAAAAAGTCTTTCACGATGCAGGCATTGACCATGTCACAGTGCAGCTGG
AACATGATACGCACATGAGTCATGAGTTACCTTGCCAACATTAG

Upstream 100 bases:

>100_bases
GAGGCCCTTGCTCTATGTTGGGCTGGCGAGGTAGAGAGTATCAGTACACATTATTTTCAATAAAGTGTCATAAATGAAAA
TATGGGCTATGCTGCACCAT

Downstream 100 bases:

>100_bases
TGTGAGGGGAACCAAACACCTGTGAGCGAGATTCCGCGTTAGTATCAAAGGCATGGGTTTTTCTACTCCAAGCTACGACC
TGATTTATCTGTTCAACCGG

Product: cation-efflux system integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSNHHHDHHNHHDHHHGAPSSSRALLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLSDSTGLIIALIAVVIGRRKAT
SQATYGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSHTVIDTRTTMVIAIIGLVFNIVGAVVLHGHSHEGVNVKGAY
LHILVDLGGSVAVIVSSLLIMTTGWMWCDTAVSVLLAVIILPRSLSLVRSTLGILMERVPKTVDVETIRSRIAQIDGVGG
VHDVHVWSIDGQQDIATVHVVVDENVNVKDCTTLDRIQKVFHDAGIDHVTVQLEHDTHMSHELPCQH

Sequences:

>Translated_307_residues
MSNHHHDHHNHHDHHHGAPSSSRALLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLSDSTGLIIALIAVVIGRRKAT
SQATYGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSHTVIDTRTTMVIAIIGLVFNIVGAVVLHGHSHEGVNVKGAY
LHILVDLGGSVAVIVSSLLIMTTGWMWCDTAVSVLLAVIILPRSLSLVRSTLGILMERVPKTVDVETIRSRIAQIDGVGG
VHDVHVWSIDGQQDIATVHVVVDENVNVKDCTTLDRIQKVFHDAGIDHVTVQLEHDTHMSHELPCQH
>Mature_306_residues
SNHHHDHHNHHDHHHGAPSSSRALLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLSDSTGLIIALIAVVIGRRKATS
QATYGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSHTVIDTRTTMVIAIIGLVFNIVGAVVLHGHSHEGVNVKGAYL
HILVDLGGSVAVIVSSLLIMTTGWMWCDTAVSVLLAVIILPRSLSLVRSTLGILMERVPKTVDVETIRSRIAQIDGVGGV
HDVHVWSIDGQQDIATVHVVVDENVNVKDCTTLDRIQKVFHDAGIDHVTVQLEHDTHMSHELPCQH

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=322, Percent_Identity=30.7453416149068, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI20070323, Length=323, Percent_Identity=28.1733746130031, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI222080086, Length=342, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI40255009, Length=342, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI21361112, Length=333, Percent_Identity=28.2282282282282, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI289803013, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI289803009, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI289803007, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI289803003, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI64762489, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI21359890, Length=266, Percent_Identity=26.6917293233083, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI14210520, Length=233, Percent_Identity=28.755364806867, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI52351208, Length=156, Percent_Identity=31.4102564102564, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI52352803, Length=128, Percent_Identity=39.84375, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786966, Length=290, Percent_Identity=37.9310344827586, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17555794, Length=324, Percent_Identity=31.1728395061728, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17555796, Length=311, Percent_Identity=31.8327974276527, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564488, Length=303, Percent_Identity=30.3630363036304, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193210990, Length=314, Percent_Identity=28.0254777070064, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17550442, Length=122, Percent_Identity=30.327868852459, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550440, Length=122, Percent_Identity=30.327868852459, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323899, Length=158, Percent_Identity=35.4430379746835, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=120, Percent_Identity=37.5, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320411, Length=238, Percent_Identity=33.6134453781513, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24645863, Length=325, Percent_Identity=28.6153846153846, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24656728, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656724, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656720, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656715, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357035, Length=331, Percent_Identity=29.9093655589124, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583858, Length=335, Percent_Identity=25.9701492537313, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24585900, Length=146, Percent_Identity=36.3013698630137, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24585898, Length=146, Percent_Identity=36.3013698630137, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24585896, Length=146, Percent_Identity=36.3013698630137, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI19921672, Length=146, Percent_Identity=36.3013698630137, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24584409, Length=147, Percent_Identity=31.9727891156463, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574430, Length=141, Percent_Identity=31.9148936170213, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33294; Mature: 33163

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHHHDHHNHHDHHHGAPSSSRALLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DSTGLIIALIAVVIGRRKATSQATYGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSH
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVIDTRTTMVIAIIGLVFNIVGAVVLHGHSHEGVNVKGAYLHILVDLGGSVAVIVSSLLI
CEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEEECCCHHHHHHHHHHH
MTTGWMWCDTAVSVLLAVIILPRSLSLVRSTLGILMERVPKTVDVETIRSRIAQIDGVGG
HHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VHDVHVWSIDGQQDIATVHVVVDENVNVKDCTTLDRIQKVFHDAGIDHVTVQLEHDTHMS
CEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
HELPCQH
CCCCCCC
>Mature Secondary Structure 
SNHHHDHHNHHDHHHGAPSSSRALLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DSTGLIIALIAVVIGRRKATSQATYGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSH
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVIDTRTTMVIAIIGLVFNIVGAVVLHGHSHEGVNVKGAYLHILVDLGGSVAVIVSSLLI
CEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEEECCCHHHHHHHHHHH
MTTGWMWCDTAVSVLLAVIILPRSLSLVRSTLGILMERVPKTVDVETIRSRIAQIDGVGG
HHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VHDVHVWSIDGQQDIATVHVVVDENVNVKDCTTLDRIQKVFHDAGIDHVTVQLEHDTHMS
CEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
HELPCQH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA